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UniProtKB - A0A1L8FG24 (A0A1L8FG24_XENLA)

Entry version 11 (31 Jul 2019)
Sequence version 1 (15 Mar 2017)
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Protein
Submitted name:

Uncharacterized protein

Gene

ncam1

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ncam1Imported
ORF Names:XELAEV_18037453mgImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus laevis (African clawed frog)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8355 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000186698 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7s

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...Xenbasei		XB-GENE-6252598 ncam1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei740 – 763HelicalSequence analysisAdd BLAST24

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini43 – 131Ig-likeInterPro annotationAdd BLAST89
Domaini136 – 209Ig-likeInterPro annotationAdd BLAST74
Domaini232 – 317Ig-likeInterPro annotationAdd BLAST86
Domaini326 – 430Ig-likeInterPro annotationAdd BLAST105
Domaini433 – 517Ig-likeInterPro annotationAdd BLAST85
Domaini526 – 625Fibronectin type-IIIInterPro annotationAdd BLAST100
Domaini627 – 723Fibronectin type-IIIInterPro annotationAdd BLAST97

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni791 – 835DisorderedSequence analysisAdd BLAST45
Regioni862 – 1034DisorderedSequence analysisAdd BLAST173
Regioni1054 – 1121DisorderedSequence analysisAdd BLAST68

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi791 – 819PolyampholyteSequence analysisAdd BLAST29
Compositional biasi862 – 905PolarSequence analysisAdd BLAST44
Compositional biasi925 – 952PolarSequence analysisAdd BLAST28
Compositional biasi981 – 1024PolarSequence analysisAdd BLAST44
Compositional biasi1056 – 1080PolarSequence analysisAdd BLAST25
Compositional biasi1081 – 1100PolyampholyteSequence analysisAdd BLAST20
Compositional biasi1105 – 1121PolarSequence analysisAdd BLAST17

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Database of Orthologous Groups

More...OrthoDBi		129648at2759

Family and domain databases

Conserved Domains Database

More...CDDi		cd00063 FN3, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.40.10, 7 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR033019 Ncam1
IPR009138 Neural_cell_adh

The PANTHER Classification System

More...PANTHERi		PTHR12231:SF239 PTHR12231:SF239, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00041 fn3, 2 hits
PF07679 I-set, 2 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01838 NCAMFAMILY

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00060 FN3, 2 hits
SM00409 IG, 5 hits
SM00408 IGc2, 5 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48726 SSF48726, 5 hits
SSF49265 SSF49265, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50853 FN3, 2 hits
PS50835 IG_LIKE, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1L8FG24-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVIFGASVTH RSSSRNSIAC RITMLHIKDL IWTLYFIGTA VALEVNIVPD 
        60         70         80         90        100
QGEISLGESK FFLCQVSGEA TDISWYSPTG EKLVTQQQIS VVRSDDYTST 
       110        120        130        140        150
LTIYNASSQD AGIYKCVASN EAEGESEGTV NLKIYQKLTF KNAPTPQEFK 
       160        170        180        190        200
EGEDAVIICD VSSSIPSIIT WRHKGKDVIF KKDVRFVVLA NNYLQIRGIK 
       210        220        230        240        250
KTDEGTYRCE GRILARGEIN YKDIQVIVNV PPTIQARQLR VNATANMAES 
       260        270        280        290        300
VVLSCDADGF PDPEISWLKK GEPIEDGEEK ISFNEDQSEM TIHHVEKDDE 
       310        320        330        340        350
AEYSCIANNQ AGEAEATILL KVYAKPKITY VENKTAVELD EITLTCEASG 
       360        370        380        390        400
DPIPSITWRT AVRNISSEAT ASWTRPLKHE TLDGHIVVKE HIRMSALTLK 
       410        420        430        440        450
DIQYTDAGEY FCIASNPIGV DMQAMYFEVQ YAPKIRGPVV VYTWEGNPVN 
       460        470        480        490        500
ITCEVFAHPR AAVTWFRDGQ LLPSSNYSNI KIYSGPTSSS LEVNPDSEND 
       510        520        530        540        550
FGNYNCTAIN TIGHEFSEFI LVQADTPSSP AIRKVEPYSS TVMIVFDEPD 
       560        570        580        590        600
STGGVPILKY KAEWRVIGHE KWHTKYYDAK EVNAESIITV MGLKPETSYT 
       610        620        630        640        650
VKLSAMNGKG LGDSTPSQEF TTQPVREPSA PKLVGHLSED GNSIKVDILK 
       660        670        680        690        700
QDDGGSPIRH YLVNYRALNA LEWKPEMRVP SNSHHVMLKA LEWNVDYEVI 
       710        720        730        740        750
VVAENQQGKS KPALLSFRTT AKPTATTATA SAGTGLGTGA IVGILIVIFV 
       760        770        780        790        800
LLLVVVDVTC FFLNKCGLLM CIAVNFCGKA GPGAKGKDIE EGKAAFSKDE 
       810        820        830        840        850
SKEPIVEVRT EEERTPNHDG SNQIEPNETT PLTEPEHPAA VEDMLPSVTT 
       860        870        880        890        900
VTTNSDTITE TFATAQNSPT SETTTLTSST APPPTTAPDS NTIQSKQATP 
       910        920        930        940        950
SKAEAPTTSS PPPTSSPKVA PLVDLSDTPT NNPSKVVANQ AGPLNPSAAT 
       960        970        980        990       1000
SAAEPPTVII KPVTTVPPNA ASPPPTPEPK QVKQEQSGTK SPEKEAAQPS 
      1010       1020       1030       1040       1050
TVKSPTEATK DESASLSNTK PLQDEDFQID GGTFKTPEID LAKDVFAALG 
      1060       1070       1080       1090       1100
TATPTAVASG KASELVSSTA DTSVPLDSAK TEKTQVEEKS KPEEIDVKST 
      1110       1120 
PAEVKTVPNE ATQTNANESK A
Length:1,121
Mass (Da):121,406
Last modified:March 15, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF6795F8C47683185
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CM004479 Genomic DNA Translation: OCT70531.1

NCBI Reference Sequences

More...RefSeqi		XP_018082335.1, XM_018226846.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		397761

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM004479 Genomic DNA Translation: OCT70531.1
RefSeqiXP_018082335.1, XM_018226846.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

GeneIDi397761

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		397761
XenbaseiXB-GENE-6252598 ncam1

Phylogenomic databases

OrthoDBi129648at2759

Family and domain databases

CDDicd00063 FN3, 2 hits
Gene3Di2.60.40.10, 7 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR033019 Ncam1
IPR009138 Neural_cell_adh
PANTHERiPTHR12231:SF239 PTHR12231:SF239, 1 hit
PfamiView protein in Pfam
PF00041 fn3, 2 hits
PF07679 I-set, 2 hits
PRINTSiPR01838 NCAMFAMILY
SMARTiView protein in SMART
SM00060 FN3, 2 hits
SM00409 IG, 5 hits
SM00408 IGc2, 5 hits
SUPFAMiSSF48726 SSF48726, 5 hits
SSF49265 SSF49265, 1 hit
PROSITEiView protein in PROSITE
PS50853 FN3, 2 hits
PS50835 IG_LIKE, 5 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1L8FG24_XENLA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1L8FG24
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 15, 2017
Last sequence update: March 15, 2017
Last modified: July 31, 2019
This is version 11 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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