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Protein

Guanylate kinase

Gene

gmk

Organism
Francisella tularensis subsp. novicida PA10-7858
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotationSAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 17ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.8UniRule annotationSAAS annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
ORF Names:N894_0773Imported
OrganismiFrancisella tularensis subsp. novicida PA10-7858Imported
Taxonomic identifieri1386968 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
Proteomesi
  • UP000180274 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 185Guanylate kinase-likeInterPro annotationAdd BLAST183

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1I9Y8X4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNNYIFIVSA PSGAGKSSLL KAFLATDIGK DNFAVAISHT TREPRVGEIN
60 70 80 90 100
SREYYFVTLA EFEQLLSQDG FIEYAKVFKN YYGTSKAELD RLLALGKNII
110 120 130 140 150
LEIDWQGAQQ TRAIYGDRAK SIFILPPSLD ELRKRLEKRN TDSKETIDYR
160 170 180 190
MEQAQSEISH ADEYDYLLVN DDFSQSLEQL CKYFEQNIQS
Length:190
Mass (Da):21,821
Last modified:February 15, 2017 - v1
Checksum:i9045E8BE0F97BF3C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP016635 Genomic DNA Translation: APA82757.1
RefSeqiWP_071304200.1, NZ_CP016635.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP016635 Genomic DNA Translation: APA82757.1
RefSeqiWP_071304200.1, NZ_CP016635.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS50052 GUANYLATE_KINASE_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1I9Y8X4_FRANO
AccessioniPrimary (citable) accession number: A0A1I9Y8X4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2017
Last sequence update: February 15, 2017
Last modified: September 27, 2017
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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