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Entry version 17 (07 Apr 2021)
Sequence version 1 (18 Jan 2017)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Macrostomum lignano
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-bindingARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMacrostomum lignanoImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri282301 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaSpiraliaLophotrochozoaPlatyhelminthesRhabditophoraMacrostomorphaMacrostomidaMacrostomidaeMacrostomum
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000095280 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei657 – 680HelicalSequence analysisAdd BLAST24
Transmembranei686 – 706HelicalSequence analysisAdd BLAST21
Transmembranei713 – 741HelicalSequence analysisAdd BLAST29
Transmembranei781 – 801HelicalSequence analysisAdd BLAST21
Transmembranei848 – 865HelicalSequence analysisAdd BLAST18
Transmembranei885 – 905HelicalSequence analysisAdd BLAST21
Transmembranei912 – 932HelicalSequence analysisAdd BLAST21
Transmembranei938 – 959HelicalSequence analysisAdd BLAST22
Transmembranei971 – 992HelicalSequence analysisAdd BLAST22
Transmembranei1012 – 1032HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni53 – 79DisorderedSequence analysisAdd BLAST27
Regioni136 – 165DisorderedSequence analysisAdd BLAST30
Regioni177 – 208DisorderedSequence analysisAdd BLAST32
Regioni575 – 605DisorderedSequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi575 – 602PolarSequence analysisAdd BLAST28

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the heat shock protein 70 family.ARBA annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.34.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029047, HSP70_peptide-bd_sf
IPR013126, Hsp_70_fam
IPR011701, MFS
IPR036259, MFS_trans_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00012, HSP70, 1 hit
PF07690, MFS_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF100920, SSF100920, 1 hit
SSF103473, SSF103473, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1I8J8I8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
AYQERDIDAA ISESKPKFDR AAIFRRTAVQ AAPKEAPEHL STMVWSAPLQ
60 70 80 90 100
AVRQDEQSRY STEGAAPAAD SELRAAASES AENLLMDAAG GSRLKKKHVE
110 120 130 140 150
DKERTRSTVN EQVKQELDAI VFGQAVNMAP VMQRASRGKQ HGWTFGSQPA
160 170 180 190 200
PPQQQQPPPP PRVIAASSAR HRGFGAAAAA PTAMRRVADR ETSRPALFGE
210 220 230 240 250
KARPSPSATD TAAQDLLLLD VLPLSVGVEI VGGRFLPIAD RNQTIPLRRR
260 270 280 290 300
VALSPYWPRQ ASLSVIFCEG ESPIAENNRR LTQLTLPIPE DDPDVGVTAW
310 320 330 340 350
VSVDANGKLE VAVTVGDWND ADWDADEDEG PIPRRRRQLI DDRTRCTSEE
360 370 380 390 400
IIKQALSKKE RDEQSFRSFL RQLQRCLDGD SDDAPGARRH RVATCAERTD
410 420 430 440 450
GAEFDELLFG SRRISLTLDH RQSPEFKALL SSTSTGRIEW SASNLAAIPV
460 470 480 490 500
PSYIASCWGR QLRTSGLTSL GESVARDVQD LLITSLTLMK LFARPAADFI
510 520 530 540 550
DCSQSQLKFV LDEAKAAGVS ELLKFANQTG SQLSWACRTL ELGTGWARWM
560 570 580 590 600
DSLGRVRKSG RYLCRIIRRR TQNTTAMSTS LESKNATSDE DAMELQSTAA
610 620 630 640 650
DDKDQQQLEK DSAKCTLWHA LICLATSLLI LVEASVPHSF GTYLVAIREE
660 670 680 690 700
TNSSLLLLNW VTVATSSVPY IMLPVSTALL AHCVNWWRLV AAISCLGMGG
710 720 730 740 750
SLLITAGQSL VPLFFLSYSL VYGVCSCALH GVVLSCLAEY FPVGHPWHVL
760 770 780 790 800
ATSLFQIGYP CAAVIFNPSA ASLINRFGWR VAMRIMAAIV AIVGTCLACL
810 820 830 840 850
LKPVGAKGLL DFSFKSDCTA AEQPAPVTAA SAVCRCCTPS QMLRRPQISI
860 870 880 890 900
WFVGKLLNYA CWFALRTNLV LYMRLAGHSL AESAGLMIAY GLGEITVCLA
910 920 930 940 950
ACLLGDRIAG RLLHVHMVAA CGMALLTGVW WFVASASYAS ALTVGCLIGA
960 970 980 990 1000
FVQLSLTFTY PAAAEVTRLD LVTAGSVTLG AGGLGILVSP LIGGLLFDLV
1010 1020 1030 1040 1050
NAYWPLFLAE SLLWMLQLLL YLAILLLTLC CFPKTYEEHL FWKARGPSLS
1060 1070 1080 1090 1100
EGLFGSEGPR RRDRHPRTTR FMYNEVFPVV LAVSMRYKPN AGITDVIDDV
Length:1,100
Mass (Da):120,086
Last modified:January 18, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB783B0B6E8DEAF04
GO

Genome annotation databases

WormBase ParaSite

More...
WBParaSitei
maker-uti_cns_0046235-snap-gene-1.14-mRNA-1; maker-uti_cns_0046235-snap-gene-1.14-mRNA-1; maker-uti_cns_0046235-snap-gene-1.14

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

WBParaSiteimaker-uti_cns_0046235-snap-gene-1.14-mRNA-1; maker-uti_cns_0046235-snap-gene-1.14-mRNA-1; maker-uti_cns_0046235-snap-gene-1.14

Family and domain databases

Gene3Di2.60.34.10, 1 hit
InterProiView protein in InterPro
IPR029047, HSP70_peptide-bd_sf
IPR013126, Hsp_70_fam
IPR011701, MFS
IPR036259, MFS_trans_sf
PfamiView protein in Pfam
PF00012, HSP70, 1 hit
PF07690, MFS_1, 1 hit
SUPFAMiSSF100920, SSF100920, 1 hit
SSF103473, SSF103473, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1I8J8I8_9PLAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1I8J8I8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 18, 2017
Last sequence update: January 18, 2017
Last modified: April 7, 2021
This is version 17 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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