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Entry version 9 (10 Apr 2019)
Sequence version 1 (18 Jan 2017)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Macrostomum lignano
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMacrostomum lignanoImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri282301 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesRhabditophoraMacrostomorphaMacrostomidaMacrostomidaeMacrostomum
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000095280 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1064 – 1210KuInterPro annotationAdd BLAST147

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.290.10, 1 hit
3.40.50.410, 1 hit
4.10.970.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006165 Ku70
IPR006164 Ku70/Ku80_beta-barrel_dom
IPR027388 Ku70_bridge/pillars_dom_sf
IPR005161 Ku_N
IPR016194 SPOC-like_C_dom_sf
IPR036465 vWFA_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR12604:SF2 PTHR12604:SF2, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02735 Ku, 1 hit
PF03731 Ku_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00559 Ku78, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF100939 SSF100939, 1 hit
SSF53300 SSF53300, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00578 ku70, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1I8IRP4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
WAACRISVPA LDKSPLRIAA LSSSGVALTA AAACGDTSHI KSCGHCTQTN
60 70 80 90 100
ALRLICMRQL VGAGCNTVNH HSREHHSAVN TTSAVNTTRG EHHSAKHHTR
110 120 130 140 150
GFKPDMKTGF SVPYGYKTTA QMRVQLETKV NREAAPCSDE LPNATYIANF
160 170 180 190 200
SMPGHLENQT FFGTYQDCVM RIMQEEFRDT CGCLGSHLAL PSDLMKRTEV
210 220 230 240 250
CHLLPEENRF NMTEYTIMNR SLAYITLSEY LQQNWDVYKD VAQRVKCFHR
260 270 280 290 300
VLQRQKSQGV WAKQCPVRCS NTRNSVTTRL ASDSWLAEVA LKDYATELIS
310 320 330 340 350
TAAARNLSTY RAANSLQACV IHDKRKVHQR PRSASKVYQS LWVGVSTITL
360 370 380 390 400
LEMVELLFHL CYLSVLKLGL LSLGKKSAGD PNAQATPHRG NDFSSSESAC
410 420 430 440 450
DFEDRESPAQ RPQLCCSRPR TLTLHLLHLL TRTIMCRVHL RHLLTRLVMC
460 470 480 490 500
RVHLCHLLTG LVMCHVHLCR LLTSTCAPPT DETGNVSCPP VPPTDETGRG
510 520 530 540 550
SNPHSEPIHG IIRWFPSIGR IFGCGVELGG GSGRSCSSLY SLLLLSKLTL
560 570 580 590 600
VGLHKHGLDV AIVAPGAVAR QDQWCLPLLI VAFESWAACR ISVPALDKSP
610 620 630 640 650
LRIAALSSSG VALTAAAACG DHMTQSAYLI SEIDAGFVAG QSSSEGFGVI
660 670 680 690 700
VLTQSVDVVR LRMVRYYSQS WAFPGSEGHS ALRWVFCPEA GFSDSKPGFL
710 720 730 740 750
YPVVGILPSK VSSPIGQRSD TAQHHQHRLI YISASSLQRI AASPLCQINQ
760 770 780 790 800
SIRNKGMAEW RGNFGIDSDE EANLDEAGRG DDGPGSRSQP SRDGLIVLID
810 820 830 840 850
CRDSMRQQAN SANQTLIKMS FKCAKTVLKR KALASDRDLV AVVLFGCGKC
860 870 880 890 900
SNPDMRHVLT LQPLEQPGAD RIKQLGHLAE LDAAALETEI GRSAPEVSIS
910 920 930 940 950
DAIWTCQSIF SACTVRLGYR RIFMLTNDDN PHDGDQHKRA QLRTKILDLQ
960 970 980 990 1000
QTEIELLIIP LLPTASGANL FDCRRFYFDN LLPENERPEQ GSDLLAELLQ
1010 1020 1030 1040 1050
NVDSKAAIRR AQVRLSIRLG PGMSLPVSVY NLTRRCTVPT AERLHRATNE
1060 1070 1080 1090 1100
RVKRTTRKFL TDTAEVLMPT DLKKAAVVNG KKVLFEQEEV KQMRRLAETG
1110 1120 1130 1140 1150
LSLIAFYPMS AMKSHYHIGP ASFIYPDEVA AQGSVCLFTG LLKACLDKNR
1160 1170 1180 1190 1200
FALCSYTPRS NAVTSLVALL PQAEVRDPDT GAQSVPPGFH LVHLPFADDF
1210
RKLTFDQEAD
Length:1,210
Mass (Da):133,338
Last modified:January 18, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4E3D600930269D48
GO

Genome annotation databases

WormBase ParaSite

More...
WBParaSitei
maker-uti_cns_0015574-snap-gene-0.2-mRNA-1; maker-uti_cns_0015574-snap-gene-0.2-mRNA-1; maker-uti_cns_0015574-snap-gene-0.2

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

WBParaSiteimaker-uti_cns_0015574-snap-gene-0.2-mRNA-1; maker-uti_cns_0015574-snap-gene-0.2-mRNA-1; maker-uti_cns_0015574-snap-gene-0.2

Family and domain databases

Gene3Di2.40.290.10, 1 hit
3.40.50.410, 1 hit
4.10.970.10, 1 hit
InterProiView protein in InterPro
IPR006165 Ku70
IPR006164 Ku70/Ku80_beta-barrel_dom
IPR027388 Ku70_bridge/pillars_dom_sf
IPR005161 Ku_N
IPR016194 SPOC-like_C_dom_sf
IPR036465 vWFA_dom_sf
PANTHERiPTHR12604:SF2 PTHR12604:SF2, 1 hit
PfamiView protein in Pfam
PF02735 Ku, 1 hit
PF03731 Ku_N, 1 hit
SMARTiView protein in SMART
SM00559 Ku78, 1 hit
SUPFAMiSSF100939 SSF100939, 1 hit
SSF53300 SSF53300, 1 hit
TIGRFAMsiTIGR00578 ku70, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1I8IRP4_9PLAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1I8IRP4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 18, 2017
Last sequence update: January 18, 2017
Last modified: April 10, 2019
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
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