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UniProtKB - A0A1I8HY28 (A0A1I8HY28_9PLAT)

Entry version 18 (10 Feb 2021)
Sequence version 1 (18 Jan 2017)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Macrostomum lignano
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMacrostomum lignanoImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri282301 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Spiralia › Lophotrochozoa › Platyhelminthes › Rhabditophora › Macrostomorpha › Macrostomida › Macrostomidae › Macrostomum
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000095280 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei135 – 159HelicalSequence analysisAdd BLAST25
Transmembranei171 – 194HelicalSequence analysisAdd BLAST24
Transmembranei238 – 257HelicalSequence analysisAdd BLAST20
Transmembranei269 – 289HelicalSequence analysisAdd BLAST21
Transmembranei325 – 347HelicalSequence analysisAdd BLAST23
Transmembranei368 – 392HelicalSequence analysisAdd BLAST25

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini150 – 433G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST284
Domaini691 – 791Ig-likeInterPro annotationAdd BLAST101
Domaini970 – 1064Ig-likeInterPro annotationAdd BLAST95
Domaini1076 – 1155Ig-likeInterPro annotationAdd BLAST80
Domaini1160 – 1245Ig-likeInterPro annotationAdd BLAST86
Domaini1256 – 1340Ig-likeInterPro annotationAdd BLAST85
Domaini1347 – 1449Ig-likeInterPro annotationAdd BLAST103
Domaini1454 – 1547Ig-likeInterPro annotationAdd BLAST94
Domaini1556 – 1659Fibronectin type-IIIInterPro annotationAdd BLAST104

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni50 – 95DisorderedSequence analysisAdd BLAST46
Regioni473 – 500DisorderedSequence analysisAdd BLAST28
Regioni521 – 549DisorderedSequence analysisAdd BLAST29
Regioni885 – 928DisorderedSequence analysisAdd BLAST44
Regioni1724 – 1747DisorderedSequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi528 – 544PolarSequence analysisAdd BLAST17
Compositional biasi885 – 916PolyampholyteSequence analysisAdd BLAST32
Compositional biasi1728 – 1747PolarSequence analysisAdd BLAST20

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisARBA annotation

Family and domain databases

Conserved Domains Database

More...CDDi		cd00063, FN3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.40.10, 7 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR017452, GPCR_Rhodpsn_7TM
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR003599, Ig_sub
IPR003598, Ig_sub2

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00060, FN3, 1 hit
SM00409, IG, 6 hits
SM00408, IGc2, 5 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48726, SSF48726, 7 hits
SSF49265, SSF49265, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50853, FN3, 1 hit
PS50262, G_PROTEIN_RECEP_F1_2, 1 hit
PS50835, IG_LIKE, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1I8HY28-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
IQFSNSEQQI QLPPEEALTS DPVLEDIVNI PETGQHREVK LSFFQLQGLR 
        60         70         80         90        100
KPKRKEEASS AGAARYLRTG GAHAGKSQPE AERANRKNRR KKSLQKMPVT 
       110        120        130        140        150
AASLMNGGNS TVDVDSDAAK EAAALELLAA VYKYLFAWLV PLLYVSGCAG 
       160        170        180        190        200
TIVCVTVLLR RGSTQKEARP WFIALSLTDL CVLSVGLPIM YLNIVRAIVK 
       210        220        230        240        250
AELSPTATVG SYDPRSWNAP ACYGLTILQY YGLIASSWVQ VGISLTRCLS 
       260        270        280        290        300
AVMPLACRRR LNYAASKRAL AVTLAVPIVL AVAAVTSSVK YYERSEANNG 
       310        320        330        340        350
TGGGGGSGGV CAQKWKSPYY FYSTLVLRVF FPAVCLAVSS AGIMYSLHRF 
       360        370        380        390        400
KRTFPTDQAR LSQQQRRISI ALIGMNSTFL LFALPYELYL IYATERRADL 
       410        420        430        440        450
QRGGPAHAAA LKIAERVFAV LMYTNNATNW IFYFVLGHRF RQELQRRLFV 
       460        470        480        490        500
CCSTPASSGK AVAQYKFRPE RAPLPVTPPL TPPPIQHRAP RQPPPPPSLE 
       510        520        530        540        550
AIDYDDSDEI VGAASEELRP LRGPRSVGDQ RWTTSGCDSG GSGSSASRRR 
       560        570        580        590        600
RERKYRDCVG YRLTSKRFAS ENLIKFFRPI FTIGEQLILT HTPGSFGSLL 
       610        620        630        640        650
LCLIRAGKHL HLFIKFLGLA ISHLPRCHWF RVFGFFWFLV FVARLPIESG 
       660        670        680        690        700
IISIDFFISK SAKTARCAAS CHNLLLQLQI VESAVVGAEF PSAAAALSVS 
       710        720        730        740        750
VSSNSGQYLS ELSNLRLHCN VSEKPDYIFW YYSTVPGGTD RAVLARCHWD 
       760        770        780        790        800
SATCAVESGF KAWANLVVMG NGTLSLAGVA RSQDGYYECE AFRDRLDAKE 
       810        820        830        840        850
GIRVVVVGPD IPVLGPDIPV LDPDIPILGP NIPVLGPDIP ILDPEILILG 
       860        870        880        890        900
PDIPVLGPDI PVLDPDIPIL GPNIPVLGPD IPVPHHQSGE KREKERHRGV 
       910        920        930        940        950
RGGLKSRGKS RIEASREAGK LVPAAASRGS RRNRRECEVF NGAFAAKRWP 
       960        970        980        990       1000
MATEKVKITQ SFSIVTGSEP SIVQSPTQLT SGDLATFSCN SGSGWNPPPR 
      1010       1020       1030       1040       1050
LTWLRNSIDK PAGDDLTALA LYSPPAAKFG PASSVLRLTV GADDHEAVLI 
      1060       1070       1080       1090       1100
CTAAQTELSN ASVSAAQLKL LVKHKPSIGS IADLTAVEGS SVPVACSAGG 
      1110       1120       1130       1140       1150
YPAPRLQLIG ANGSVMQESA SGMFTLYPVD RSQAGALACR AVNPLGTATA 
      1160       1170       1180       1190       1200
AFRLSVLYQP TVRTPASAVV DAGGSVTLPC SVDGNPPPAE LVWRHDATGA 
      1210       1220       1230       1240       1250
ALPPSSDGAL RLDGADPRRH AGVWHCEARS ILTASSGPPT EYTASSAVVL 
      1260       1270       1280       1290       1300
TVRYRPGLPQ ASQPRSPLLA GESVNLTCQP SQVSPGEPAP SLAWVRIQSS 
      1310       1320       1330       1340       1350
PVHLPAGPSV RFSPVGLSDS GSYACRAVND LGTSESAPVS LLVHQAPSLT 
      1360       1370       1380       1390       1400
VESAPTGANA ARVGSTNFRL VCRVRANPAP RLRWLRNGAR MPPELFTELA 
      1410       1420       1430       1440       1450
GLGDQSFEYQ LTLHFRGFQR SVLRLNDTGV YQCFADNELG NSTAEHRLEV 
      1460       1470       1480       1490       1500
LTQPSIVNAF DKAAFVPGRR PALACQFISH SGFSVTWRTP DGRTLTTGSA 
      1510       1520       1530       1540       1550
QPVEEANGQP WWMTSPAPLA DGGSQPAIGN YTCQVNNSLG TVQRRLQLVA 
      1560       1570       1580       1590       1600
ASAPDPPERL SAAPLAWDSV RLFWKPGFDG GHPAKLRLRL VGWNASVGAR 
      1610       1620       1630       1640       1650
MPTSPPLLVD AEVGEATIGG LYPDTAYDVV CVAENRLGES PAFGAADNNA 
      1660       1670       1680       1690       1700
AVVVTTGHLR LPQVRDASWD PATGRLVFRG QPGYCARVEA SSDAGATWRA 
      1710       1720       1730       1740       1750
PPNADAVGCL AFQADGLSVA TAPASVPADA SPSESASSST GSLTSTSSEA 
      1760 
RRTEILYRVS LCLANRT
Length:1,767
Mass (Da):189,425
Last modified:January 18, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD5065BB21BF211DD
GO

Genome annotation databases

WormBase ParaSite

More...WBParaSitei		maker-uti_cns_0008474-snap-gene-0.2-mRNA-1; maker-uti_cns_0008474-snap-gene-0.2-mRNA-1; maker-uti_cns_0008474-snap-gene-0.2

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

WBParaSiteimaker-uti_cns_0008474-snap-gene-0.2-mRNA-1; maker-uti_cns_0008474-snap-gene-0.2-mRNA-1; maker-uti_cns_0008474-snap-gene-0.2

Family and domain databases

CDDicd00063, FN3, 1 hit
Gene3Di2.60.40.10, 7 hits
InterProiView protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR017452, GPCR_Rhodpsn_7TM
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR003599, Ig_sub
IPR003598, Ig_sub2
SMARTiView protein in SMART
SM00060, FN3, 1 hit
SM00409, IG, 6 hits
SM00408, IGc2, 5 hits
SUPFAMiSSF48726, SSF48726, 7 hits
SSF49265, SSF49265, 1 hit
PROSITEiView protein in PROSITE
PS50853, FN3, 1 hit
PS50262, G_PROTEIN_RECEP_F1_2, 1 hit
PS50835, IG_LIKE, 7 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1I8HY28_9PLAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1I8HY28
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 18, 2017
Last sequence update: January 18, 2017
Last modified: February 10, 2021
This is version 18 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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