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Entry version 12 (07 Apr 2021)
Sequence version 1 (22 Nov 2017)
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Protein
Submitted name:

Hydrophobic/amphiphilic exporter-1, HAE1 family

Gene

SAMN04515674_10662

Organism
Pseudarcicella hirudinis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Hydrophobic/amphiphilic exporter-1, HAE1 familyImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:SAMN04515674_10662Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPseudarcicella hirudinisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1079859 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaePseudarcicella
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000199306 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei12 – 34HelicalSequence analysisAdd BLAST23
Transmembranei338 – 357HelicalSequence analysisAdd BLAST20
Transmembranei364 – 384HelicalSequence analysisAdd BLAST21
Transmembranei431 – 451HelicalSequence analysisAdd BLAST21
Transmembranei463 – 489HelicalSequence analysisAdd BLAST27
Transmembranei524 – 543HelicalSequence analysisAdd BLAST20
Transmembranei857 – 875HelicalSequence analysisAdd BLAST19
Transmembranei882 – 902HelicalSequence analysisAdd BLAST21
Transmembranei908 – 933HelicalSequence analysisAdd BLAST26
Transmembranei954 – 977HelicalSequence analysisAdd BLAST24
Transmembranei983 – 1011HelicalSequence analysisAdd BLAST29

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1020 – 1040DisorderedSequence analysisAdd BLAST21

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.2090.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027463, AcrB_DN_DC_subdom
IPR001036, Acrflvin-R

The PANTHER Classification System

More...
PANTHERi
PTHR32063, PTHR32063, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00873, ACR_tran, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00702, ACRIFLAVINRP

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF82714, SSF82714, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1I5TK94-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNISELSLKR PVLATVMNIL IILFGVVGFT FLAVRDYPAI DPPIVTVNTS
60 70 80 90 100
YTGANADIIE NQITEPLEKQ INGIPGIRSI TSSSSLGSSF ITVEFNLDVQ
110 120 130 140 150
LEAAASDVRD KVGQAVRNLP QDIDAPPVVS KADANSDFIL LLAIQSRTKG
160 170 180 190 200
LLELSDYAEN VLQQRFQTIN DVSGVNILGQ KRYAMRIWLK PDKMNAFGLS
210 220 230 240 250
FTDIQTALAK ENVEIPAGKI YGNNTEMTIR ALGRLTTEQQ FRDLIIQETD
260 270 280 290 300
QGIIRLGDIA SIELGPENLE QSWKYNGVYA VGLAVVPQPG ANYIKIADEF
310 320 330 340 350
NKRLQEIEKE NKSDIQFKLL IDNTKNVRRS LEEVEETLII SFGLVVLVIF
360 370 380 390 400
FFFRNWLIAI RPLIDIPISL IATFFVMYLA GFTINVLTLL AIVLATGLVV
410 420 430 440 450
DDGIVVTENI FRKLEQGFPI RKAALEGSKE IFFAVISTSL TLAVVFLPVI
460 470 480 490 500
FLQGFVGSLF REFGIVVAGA VLISAFVSLT ITPVLNVYLN RKDAGHGWLY
510 520 530 540 550
NKTEPFFTGM ESGYKGFLKS FMKVRWMAWV VVAICGGLIY FSGKNLQSEI
560 570 580 590 600
APMEDKSSVR FSMTAPEGSS YTYMQDVSDR LTNFLNDSIP EREFVFNAVP
610 620 630 640 650
GFGGNGGANT SIARIGLVDP DKRTRSQDDI AKMLNKKVSK FNNARIFGIQ
660 670 680 690 700
EQTISVGLGS RGSLPVQFVI QNIDLAKIKD AVPKFLEAAR NEKTFQNVDV
710 720 730 740 750
NLKFNKPEIL MTFDRIKIKD LGLSTQDVVS AVQGAFSGRR LAYFTMNGRQ
760 770 780 790 800
YQVIAQVERK DRSEPNDIEN LFVTNSRGER IPLSAVVKIE ESSNPSTLYH
810 820 830 840 850
FNRLKSATIS ASLAEGKTIG DGVKAMQAIA SKVLDNSFQT SLNGPSRDYA
860 870 880 890 900
ESSSNTSFAF GLALALIYLL LAAQFESFKD PFIIMVTVPL ALAGALGSLW
910 920 930 940 950
LFGQTLNIFS QIGMIMLIGL VTKNGILIVE FANQKREEGM PKMQAVVEAA
960 970 980 990 1000
TQRLRPILMT SLATALGALP IALSLGAAST SRIPLGIVVV GGIMFSLILT
1010 1020 1030 1040
LLVIPAVYTF ISSHHHKAES LEVEEEEEQQ QEFDSSALRN
Length:1,040
Mass (Da):114,476
Last modified:November 22, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE9DD8DA7055CFB6D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
FOXH01000006 Genomic DNA Translation: SFP82776.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
SFP82776; SFP82776; SAMN04515674_10662

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FOXH01000006 Genomic DNA Translation: SFP82776.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiSFP82776; SFP82776; SAMN04515674_10662

Family and domain databases

Gene3Di3.30.2090.10, 2 hits
InterProiView protein in InterPro
IPR027463, AcrB_DN_DC_subdom
IPR001036, Acrflvin-R
PANTHERiPTHR32063, PTHR32063, 1 hit
PfamiView protein in Pfam
PF00873, ACR_tran, 1 hit
PRINTSiPR00702, ACRIFLAVINRP
SUPFAMiSSF82714, SSF82714, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1I5TK94_9BACT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1I5TK94
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: April 7, 2021
This is version 12 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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