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Protein

Pyruvate dehydrogenase E1 component subunit alpha

Gene

pdhA

Organism
Flavobacterium ummariense
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.UniRule annotation

Catalytic activityi

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.UniRule annotation

Cofactori

thiamine diphosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandPyruvateUniRule annotationImported, Thiamine pyrophosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate dehydrogenase E1 component subunit alphaUniRule annotation (EC:1.2.4.1UniRule annotation)
Gene namesi
Name:pdhAUniRule annotation
ORF Names:SAMN05421741_11097Imported
OrganismiFlavobacterium ummarienseImported
Taxonomic identifieri913024 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeFlavobacterium
Proteomesi
  • UP000199036 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Interactioni

Subunit structurei

Heterodimer of an alpha and a beta chain.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 311E1_dhInterPro annotationAdd BLAST297

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili286 – 306Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR001017 DH_E1
IPR017597 Pyrv_DH_E1_asu_subgrp-y
IPR029061 THDP-binding
PfamiView protein in Pfam
PF00676 E1_dh, 1 hit
SUPFAMiSSF52518 SSF52518, 1 hit
TIGRFAMsiTIGR03182 PDH_E1_alph_y, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1I5BR83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEITKEVYL KWYEDMQFWR KFEDKLAALY IQQKVRGFLH LYNGQEAVLA
60 70 80 90 100
GALHAMDLSK DKMITAYRNH VQPIGMGVDP RRVMAELLGK ATGTSQGLGG
110 120 130 140 150
SMHIFSKEHG FYGGHGIVGA QIPVGAGMAF ADKYLETGGV SLTYFGDGAA
160 170 180 190 200
RQGSLHEAFN MAMLWKLPVV FICENNGYAM GTSVERTANH TDIWKLGLGY
210 220 230 240 250
EMPSYAVDAM NPVKVAEAMF DAMERARRGE GPTFLEMKTY RYRGHSMSDA
260 270 280 290 300
QHYRTKDEVE EYRKIDPITQ VLDVIKENNW ATDEEIETID QRVRDLVSEC
310 320 330
EKFAEESPYP DTNVMYDVVY DQENYPFIPH KL
Length:332
Mass (Da):37,751
Last modified:November 22, 2017 - v1
Checksum:i9EEC069983735B36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FOVI01000010 Genomic DNA Translation: SFN77168.1

Similar proteinsi

Entry informationi

Entry nameiA0A1I5BR83_9FLAO
AccessioniPrimary (citable) accession number: A0A1I5BR83
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: January 31, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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