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Protein

Acetaldehyde dehydrogenase

Gene

SAMN05216603_101486

Organism
Pseudomonas benzenivorans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD+ and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

Acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei132Acyl-thioester intermediateUniRule annotation1
Binding sitei290NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi163 – 171NADUniRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotation
Biological processAromatic hydrocarbons catabolismUniRule annotationSAAS annotation
LigandNADUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Acetaldehyde dehydrogenaseUniRule annotationSAAS annotation (EC:1.2.1.10UniRule annotation)
Alternative name(s):
Acetaldehyde dehydrogenase [acetylating]UniRule annotation
Gene namesi
ORF Names:SAMN05216603_101486Imported
OrganismiPseudomonas benzenivoransImported
Taxonomic identifieri556533 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000199168 Componenti: Unassembled WGS sequence

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 124Semialdhyde_dhInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the acetaldehyde dehydrogenase family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_01657 Ac_ald_DH_ac, 1 hit
InterProiView protein in InterPro
IPR003361 Acetaldehyde_dehydrogenase
IPR015426 Acetylaldehyde_DH_C
IPR036291 NAD(P)-bd_dom_sf
IPR000534 Semialdehyde_DH_NAD-bd
PfamiView protein in Pfam
PF09290 AcetDehyd-dimer, 1 hit
PF01118 Semialdhyde_dh, 1 hit
PIRSFiPIRSF015689 Actaldh_dh_actl, 1 hit
SMARTiView protein in SMART
SM00859 Semialdhyde_dh, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR03215 ac_ald_DH_ac, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1G7TRF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQKLKVAII GPGNIGTDLM IKVLRNAKYL EMGAMVGIDA ASDGLARAQR
60 70 80 90 100
MGVATTHAGV EGLIKLPEFA DIDFVFDATS ASAHVQNEAL LRQAKPGIRL
110 120 130 140 150
IDLTPAAIGP YCVPVVNLEE HLGKLNVNMV TCGGQATIPM VAAVSRVAKV
160 170 180 190 200
HYAEIVASIS SKSAGPGTRA NIDEFTETTS KAIEVIGGAA KGKAIIIMNP
210 220 230 240 250
AEPPLIMRDT VYVLSAAADQ AAVAASVEEM VQAVQAYVPG YRLKQQVQFD
260 270 280 290 300
VIPESAPLNI PGLGRFSGLK TSVFLEVEGA AHYLPAYAGN LDIMTSAALA
310
TAERMAQSML KA
Length:312
Mass (Da):32,711
Last modified:November 22, 2017 - v1
Checksum:i60D3F74568E13E52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FNCT01000001 Genomic DNA Translation: SDG37858.1

Similar proteinsi

Entry informationi

Entry nameiA0A1G7TRF3_9PSED
AccessioniPrimary (citable) accession number: A0A1G7TRF3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: January 31, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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