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Protein

Pyruvate dehydrogenase E1 component subunit alpha

Gene

pdhA

Organism
Cloacibacterium normanense
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.UniRule annotation

Cofactori

thiamine diphosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandPyruvateUniRule annotationImported, Thiamine pyrophosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate dehydrogenase E1 component subunit alphaUniRule annotation (EC:1.2.4.1UniRule annotation)
Gene namesi
Name:pdhAUniRule annotationImported
ORF Names:BHF72_2226Imported
OrganismiCloacibacterium normanenseImported
Taxonomic identifieri237258 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceae
Proteomesi
  • UP000095601 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Interactioni

Subunit structurei

Heterodimer of an alpha and a beta chain.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 312E1_dhInterPro annotationAdd BLAST298

Family and domain databases

InterProiView protein in InterPro
IPR001017 DH_E1
IPR017597 Pyrv_DH_E1_asu_subgrp-y
IPR029061 THDP-binding
PfamiView protein in Pfam
PF00676 E1_dh, 1 hit
SUPFAMiSSF52518 SSF52518, 1 hit
TIGRFAMsiTIGR03182 PDH_E1_alph_y, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1E5UEM7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEFSKEVYL QWYADMTMWR RFEDKCRSLY LKQKIRGFLH LYNGQEAIPA
60 70 80 90 100
GFVHAMDLTK DAMITAYRCH VHPMAMGVDP KRIMAELCGK ATGTSNGLGG
110 120 130 140 150
SMHIFSKEHR FYGGHGIVGG QIPLGAGIAF ADKYFERGGV TICYFGDGAV
160 170 180 190 200
RQGALHETFN MAMNWKLPVV FVVENNQYAM GTSVSRTANH EDIYKLGLGY
210 220 230 240 250
EMPCMPVDAM DPEKVAEVAY EAVERARRGD GPTFIEARTY RFRGHSMSDA
260 270 280 290 300
EPYRTKEEVA LKKEEDPIVL VKNRILENKW ATEEELATIE EKSKMFVEEC
310 320 330
EAFAEESPYP SAEKVYEYVY SEPNYPFLDK LEN
Length:333
Mass (Da):37,945
Last modified:January 18, 2017 - v1
Checksum:iB10D2D454CEC3522
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MKGI01000043 Genomic DNA Translation: OEL11356.1
RefSeqiWP_069798380.1, NZ_MKGI01000043.1

Genome annotation databases

EnsemblBacteriaiOEL11356; OEL11356; BHF72_2226
PATRICifig|237258.4.peg.2387

Similar proteinsi

Entry informationi

Entry nameiA0A1E5UEM7_9FLAO
AccessioniPrimary (citable) accession number: A0A1E5UEM7
Entry historyiIntegrated into UniProtKB/TrEMBL: January 18, 2017
Last sequence update: January 18, 2017
Last modified: June 7, 2017
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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