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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Staphylococcus equorum
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi490MagnesiumUniRule annotation1
Metal bindingi496MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotationSAAS annotation, RNA-bindingUniRule annotationSAAS annotation, Transferase
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
ORF Names:AST02_04590Imported
OrganismiStaphylococcus equorumImported
Taxonomic identifieri246432 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000095586 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini626 – 699S1 motifInterPro annotationAdd BLAST74

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR036456 PNPase_PH_RNA-bd_sf
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 2 hits
PF00575 S1, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF46915 SSF46915, 1 hit
SSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1E5TU33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQEKKVFKT EWANRSLTIE TGQLAKQANG AVLVRYGDTV VLSTAVASKE
60 70 80 90 100
PRDVDFFPLM VNYEEKMYAA GKIPGGFKKR EGRPSDEATL TARLIDRPIR
110 120 130 140 150
PLFPKGYKHD VQIMNTVLSA DPDCSPEMAA MIGSSMALSV SDIPFQGPIA
160 170 180 190 200
GVNVGYVDGE YVINPTVAQK EVSRLDLEVA GHKDAVNMVE AGASEITESE
210 220 230 240 250
MLEGIFFGHN EIQRLVNFQQ EIVDHIQPVK TPFTPVEQDE TLAEKVKQLT
260 270 280 290 300
EANGLKEAVL TFDKQQRDIN LDTLKEKVVS EFIDEEDVNN AALIKDVHGI
310 320 330 340 350
LNSLVKEEVR RLIAEEKIRP DGRKSDEIRP LESEVGVLPR VHGSGLFTRG
360 370 380 390 400
QTQALSVLTL GSMSEYQILD GLGEEQQKRF MHHYNFPNYS VGETGPVRSP
410 420 430 440 450
GRREIGHGAL GERALSHVIP DTKDFPYTVR IVSEVLESNG SSSQASICGS
460 470 480 490 500
TLALMDAGVP IKAPVAGIAM GLVTRDDSYT ILTDIQGMED ALGDMDFKVA
510 520 530 540 550
GTSEGITAIQ MDIKIDGLTK EIIREALDQA REGRLAILDH MLQTIDTTRG
560 570 580 590 600
ELSAFAPKVV TMTIKPEKIR DVIGPGGKKI NEIIDQTGVK LDIEQDGTIF
610 620 630 640 650
IGAVDKDAIA EARSIIEDIT REAEVGQVYE GKVKRIEKYG AFVELFPGKD
660 670 680 690
ALVHISQIAN ERIDKVEDVL KIGDTFKIKV TEIDKQGRVN ASHKVLLSN
Length:699
Mass (Da):76,759
Last modified:January 18, 2017 - v1
Checksum:i6CE2C44ED249379F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LNNB01000009 Genomic DNA Translation: OEK70738.1
RefSeqiWP_069816004.1, NZ_LNNB01000009.1

Genome annotation databases

EnsemblBacteriaiOEK70738; OEK70738; AST02_04590

Similar proteinsi

Entry informationi

Entry nameiA0A1E5TU33_9STAP
AccessioniPrimary (citable) accession number: A0A1E5TU33
Entry historyiIntegrated into UniProtKB/TrEMBL: January 18, 2017
Last sequence update: January 18, 2017
Last modified: February 28, 2018
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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