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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Nitrosomonadales bacterium SCN 54-20
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationSAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi), Glucose-6-phosphate isomerase (ABS69_15935)
  3. Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfp), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfp)
  4. Fructose-bisphosphate aldolase (ABS69_12130), Fructose-1,6-bisphosphate aldolase (ABS69_23070), Fructose-bisphosphate aldolase (ABS69_02640), Fructose-1,6-bisphosphate aldolase (ABS69_23140)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei385UniRule annotation1
Active sitei505UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processGluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181
UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
ORF Names:ABS69_07670Imported
OrganismiNitrosomonadales bacterium SCN 54-20Imported
Taxonomic identifieri1660164 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadales

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1E4G5M5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITPLMQRPA WKALEVHCQA IKGMHLRQLF ADDPKRGERF TVEAAGLYLD
60 70 80 90 100
YSKNRITDET LHLLVQLAEE CGLRERIEAM FRGDAINVTE QRAVLHIALR
110 120 130 140 150
APRNEKILVD GNDVVPGVHA VLDRMSDFSD RVRNGDWQGH TGKRIRNIIN
160 170 180 190 200
IGIGGSDLGP VMAYEALRHY SLHNLSFRFI SNVDGTDFVE ATRGLDPEET
210 220 230 240 250
LFIICSKTFT TTETLTNAHT ARRWMLRQMK DMDGVRKHFV AVSTNAEEVA
260 270 280 290 300
KFGIDTANMF EFWDWVGGRY SMDSAIGLST MIAIGPENFR EMLAGFHAMD
310 320 330 340 350
QHFHSAPFDR NLPVLMGLLS LWYNNFFGAQ TLAVLPYAQY LKRFPAYLQQ
360 370 380 390 400
LTMESNGKHI TLDGAHVDYQ TSPIVWGEPG TNGQHSFYQL IHQGTRLIPC
410 420 430 440 450
DFIGFCQTLN PLGDHHELLM ANLFAQTEAL AFGKTEDEVK AEGVPDWLCP
460 470 480 490 500
HRSFEGNHPT NTILAERLTP HTLGALVALY EQSVFTQGII WQIDSFDQWG
510 520 530 540
VELGKVLARR IKQELEDESS EPLKHDSSTN TLIQRYNRMK QK
Length:542
Mass (Da):61,504
Last modified:January 18, 2017 - v1
Checksum:iCD764A93F4230DEA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MEEO01000065 Genomic DNA Translation: ODT78674.1

Similar proteinsi

Entry informationi

Entry nameiA0A1E4G5M5_9PROT
AccessioniPrimary (citable) accession number: A0A1E4G5M5
Entry historyiIntegrated into UniProtKB/TrEMBL: January 18, 2017
Last sequence update: January 18, 2017
Last modified: April 25, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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