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UniProtKB - A0A1D8PS16 (A0A1D8PS16_CANAL)

Entry version 22 (19 Jan 2022)
Sequence version 1 (18 Jan 2017)
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Protein

Phenylalanyl-tRNA synthetase beta subunit

Gene

FRS1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAminoacyl-tRNA synthetaseARBA annotation, Ligase
Biological processProtein biosynthesisARBA annotation
LigandATP-bindingARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phenylalanyl-tRNA synthetase beta subunitARBA annotation (EC:6.1.1.20ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FRS1Imported
Ordered Locus Names:CAALFM_CR01760CAImported, orf19.2573Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri237561 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Candida/Lodderomyces clade › Candida ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000559 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome R

Organism-specific databases

Candida Genome Database

More...CGDi		CAL0000190210, FRS1

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		FungiDB:CR_01760C_A

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Tetramer of two alpha and two beta subunits.

ARBA annotation

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		237561.A0A1D8PS16

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		A0A1D8PS16

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini291 – 369B5InterPro annotationAdd BLAST79

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2472, Eukaryota

Identification of Orthologs from Complete Genome Data

More...OMAi		FPGRCAN

Database of Orthologous Groups

More...OrthoDBi		378921at2759

Family and domain databases

Conserved Domains Database

More...CDDi		cd00769, PheRS_beta_core, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.930.10, 1 hit
3.50.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR045864, aa-tRNA-synth_II/BPL/LPL
IPR005146, B3/B4_tRNA-bd
IPR009061, DNA-bd_dom_put_sf
IPR045060, Phe-tRNA-ligase_IIc_bsu
IPR004531, Phe-tRNA-synth_IIc_bsu_arc_euk
IPR020825, Phe-tRNA_synthase-like_B3/B4
IPR041616, PheRS_beta_core
IPR040659, PhetRS_B1
IPR005147, tRNA_synthase_B5-dom

The PANTHER Classification System

More...PANTHERi		PTHR10947, PTHR10947, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03483, B3_4, 1 hit
PF03484, B5, 1 hit
PF18262, PhetRS_B1, 1 hit
PF17759, tRNA_synthFbeta, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00873, B3_4, 1 hit
SM00874, B5, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46955, SSF46955, 2 hits
SSF55681, SSF55681, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00471, pheT_arch, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51483, B5, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1D8PS16-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPTIPVDKED LFKLLGRSYT TEEFDELCFQ FGIELDEDTT EDVKGTDERP 
        60         70         80         90        100
QLKIEVPANR YDMLCIEGIA QALNEFLGNT SAPNYKLSPS KPEISLTIKE 
       110        120        130        140        150
STYPIRQYAA SAILRNVNLD ERAYDSFIAL QDKLHANLCR NRTLVAIGTH 
       160        170        180        190        200
DLDTLTPPFT YEALAPKDIV FKPLNQTKEI NGEELMEFYE KDKNIGKFLH 
       210        220        230        240        250
IIKDSPVYPV MLDANRTVAS LPPIINSDHS KITLNTKNVW IDVTGTDRTK 
       260        270        280        290        300
TEIVINQLVA MFSRYCKEPF EIEPIQIISE HNNETRVCPN ITPRTAKAEI 
       310        320        330        340        350
SYINSCVGLD YSGEEISKLL KKMSLDATPS TEERDILDVK IPITRSDILH 
       360        370        380        390        400
QCDIMEDVAI GYGYDNLKKT KPKAESLVAA PLPVNKVADI LRLASSQAGY 
       410        420        430        440        450
LEVMPLTLSS HDENFAWLKQ KDDGTKAVKL ENPKTIEYQV VRTTLLPGIL 
       460        470        480        490        500
KTVKENRKHS LPIKVFECGD IVLKNPELER GAFNQRNWAA LYVGKTSGFE 
       510        520        530        540        550
MVQGLLGKIM QTMRTPWLEN PSKDQRRGYW IEEDKENTTF FPGRGAKIYF 
       560        570        580        590 
RNADNAEAKA IGSIGVLHPE VMNNFDIPYA ASSVEINAEV FL
Length:592
Mass (Da):66,836
Last modified:January 18, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6CAA8FCC4F1AC9D8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CP017630 Genomic DNA Translation: AOW30935.1

NCBI Reference Sequences

More...RefSeqi		XP_718239.2, XM_713146.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		3640121

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		cal:CAALFM_CR01760CA

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017630 Genomic DNA Translation: AOW30935.1
RefSeqiXP_718239.2, XM_713146.2

3D structure databases

SMRiA0A1D8PS16
ModBaseiSearch...

Protein-protein interaction databases

STRINGi237561.A0A1D8PS16

Genome annotation databases

GeneIDi3640121
KEGGical:CAALFM_CR01760CA

Organism-specific databases

CGDiCAL0000190210, FRS1
VEuPathDBiFungiDB:CR_01760C_A

Phylogenomic databases

eggNOGiKOG2472, Eukaryota
OMAiFPGRCAN
OrthoDBi378921at2759

Family and domain databases

CDDicd00769, PheRS_beta_core, 1 hit
Gene3Di3.30.930.10, 1 hit
3.50.40.10, 1 hit
InterProiView protein in InterPro
IPR045864, aa-tRNA-synth_II/BPL/LPL
IPR005146, B3/B4_tRNA-bd
IPR009061, DNA-bd_dom_put_sf
IPR045060, Phe-tRNA-ligase_IIc_bsu
IPR004531, Phe-tRNA-synth_IIc_bsu_arc_euk
IPR020825, Phe-tRNA_synthase-like_B3/B4
IPR041616, PheRS_beta_core
IPR040659, PhetRS_B1
IPR005147, tRNA_synthase_B5-dom
PANTHERiPTHR10947, PTHR10947, 1 hit
PfamiView protein in Pfam
PF03483, B3_4, 1 hit
PF03484, B5, 1 hit
PF18262, PhetRS_B1, 1 hit
PF17759, tRNA_synthFbeta, 1 hit
SMARTiView protein in SMART
SM00873, B3_4, 1 hit
SM00874, B5, 1 hit
SUPFAMiSSF46955, SSF46955, 2 hits
SSF55681, SSF55681, 1 hit
TIGRFAMsiTIGR00471, pheT_arch, 1 hit
PROSITEiView protein in PROSITE
PS51483, B5, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1D8PS16_CANAL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1D8PS16
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 18, 2017
Last sequence update: January 18, 2017
Last modified: January 19, 2022
This is version 22 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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