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Entry version 19 (11 Dec 2019)
Sequence version 1 (18 Jan 2017)
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Protein

Agglutinin-like protein 4

Gene

ALS4

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion, Virulence

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Agglutinin-like protein 4
Alternative name(s):
Adhesin 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ALS4
Synonyms:ALS12
Ordered Locus Names:CAALFM_C604130CA
ORF Names:orf19.4555, orf19.4556
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri237561 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000559 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Candida Genome Database

More...
CGDi
CAL0000174423, ALS4

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:C6_04130C_A

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Cell wall, Membrane, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Sequence analysisAdd BLAST17
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000043916618 – 2078Agglutinin-like protein 4Add BLAST2061
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_00004391672079 – 2100Removed in mature formSequence analysisAdd BLAST22

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi73 ↔ 150By similarity
Disulfide bondi96 ↔ 112By similarity
Disulfide bondi205 ↔ 298By similarity
Disulfide bondi227 ↔ 256By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi831N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1083N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1335N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1407N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1443N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1479N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1551N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1587N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1623N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1659N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1766N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1850N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi2014N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi2036N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi2078GPI-anchor amidated glycineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated and O-glycosylated.Curated
The GPI-anchor is attached to the protein in the endoplasmic reticulum and serves to target the protein to the cell surface. There, the glucosamine-inositol phospholipid moiety is cleaved off and the GPI-modified mannoprotein is covalently attached via its lipidless GPI glycan remnant to the 1,6-beta-glucan of the outer cell wall layer.1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A1D8PQB9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati365 – 396ALS 1Add BLAST32
Repeati401 – 432ALS 2Add BLAST32
Repeati438 – 469ALS 3Add BLAST32
Repeati474 – 505ALS 4Add BLAST32
Repeati510 – 541ALS 5Add BLAST32
Repeati546 – 577ALS 6Add BLAST32
Repeati582 – 613ALS 7Add BLAST32
Repeati618 – 649ALS 8Add BLAST32
Repeati654 – 685ALS 9Add BLAST32
Repeati690 – 721ALS 10Add BLAST32
Repeati726 – 757ALS 11Add BLAST32
Repeati762 – 793ALS 12Add BLAST32
Repeati798 – 829ALS 13Add BLAST32
Repeati834 – 865ALS 14Add BLAST32
Repeati870 – 901ALS 15Add BLAST32
Repeati906 – 937ALS 16Add BLAST32
Repeati942 – 973ALS 17Add BLAST32
Repeati978 – 1009ALS 18Add BLAST32
Repeati1014 – 1045ALS 19Add BLAST32
Repeati1050 – 1078ALS 20Add BLAST29
Repeati1086 – 1117ALS 21Add BLAST32
Repeati1122 – 1153ALS 22Add BLAST32
Repeati1158 – 1189ALS 23Add BLAST32
Repeati1194 – 1225ALS 24Add BLAST32
Repeati1230 – 1261ALS 25Add BLAST32
Repeati1266 – 1297ALS 26Add BLAST32
Repeati1302 – 1333ALS 27Add BLAST32
Repeati1338 – 1369ALS 28Add BLAST32
Repeati1374 – 1405ALS 29Add BLAST32
Repeati1410 – 1441ALS 30Add BLAST32
Repeati1446 – 1477ALS 31Add BLAST32
Repeati1482 – 1513ALS 32Add BLAST32
Repeati1518 – 1549ALS 33Add BLAST32
Repeati1554 – 1585ALS 34Add BLAST32
Repeati1590 – 1621ALS 35Add BLAST32
Repeati1626 – 1657ALS 36Add BLAST32
Repeati1662 – 1693ALS 37Add BLAST32
Repeati1698 – 1726ALS 38Add BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi326 – 2075Thr-richPROSITE-ProRule annotationAdd BLAST1750
Compositional biasi1730 – 1802Ser-richPROSITE-ProRule annotationAdd BLAST73

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Each ALS protein has a similar three-domain structure, including a N-ter domain of 433-436 amino acids that is 55-90 percent identical across the family and which mediates adherence to various materials; a central domain of variable numbers of tandemly repeated copies of a 36 amino acid motif; and a C-ter; domain that is relatively variable in length and sequence across the family.1 Publication

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ALS family.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K22493

Database of Orthologous Groups

More...
OrthoDBi
1428896at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.1280, 1 hit
2.60.40.2430, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008966, Adhesion_dom_sf
IPR008440, Agglutinin-like_ALS_rpt
IPR024672, Agglutinin-like_N
IPR043063, Agglutinin-like_N_N2
IPR033504, ALS
IPR011252, Fibrogen-bd_dom1

The PANTHER Classification System

More...
PANTHERi
PTHR33793, PTHR33793, 7 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05792, Candida_ALS, 38 hits
PF11766, Candida_ALS_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01056, Candida_ALS_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49401, SSF49401, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

A0A1D8PQB9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLQFLLLSL CVSVATAKVI TGIFDSFNSL TWTNAASYSY RGPANPTWTA
60 70 80 90 100
VIGWSLDGAT ASAGDTFTLD MPCVFKFITD QTSIDLVADG RTYATCNLNS
110 120 130 140 150
AEEFTTFSSV SCTVTTTMTA DTKAIGTVTL PFSFSVGGSG SDVDLANSQC
160 170 180 190 200
FTAGINTVTF NDGDTSISTT VDFEKSTVAS SDRILLSRIL PSLSQAVSLF
210 220 230 240 250
LPQECANGYT SGTMGFSTAG TGATIDCSTV HVGISNGLND WNYPISSESF
260 270 280 290 300
SYTKTCTSTS VLVTYQNVPA GYRPFVDAYV SATRVSSYAM RYTNIYACVG
310 320 330 340 350
AASVDDSFTH TWSGYSNSQA GSNGITIVVT TRTVTDSTTA VTTLPFNSES
360 370 380 390 400
DKTKTIEILQ PIPTTTITTS YVGVTTSYST KTAPIGETAT VIVDVPYHTT
410 420 430 440 450
TTVTSEWTGT ITTTTTRTNP TDSIDTVVVQ VPSPNPTVTT TEYWSQSYAT
460 470 480 490 500
TTTVTAPPGG TDSVIIREPP NPTVTTTEYW SQSYATTTTV TAPPGGTDSV
510 520 530 540 550
IIREPPNPTV TTTEYWSQSY ATTTTVTAPP GGTDSVIIRE PPNPTVTTTE
560 570 580 590 600
YWSQSYATTT TVTAPPGGTD SVIIREPPNP TVTTTEYWSQ SYATTTTVTA
610 620 630 640 650
PPGGTDSVII REPPNPTVTT TEYWSQSFAT TTTVTAPPGG TDSVIIREPP
660 670 680 690 700
NPTVTTTEYW SQSFATTTTV TAPPGGTDSV IIREPPNPTV TTTEYWSQSY
710 720 730 740 750
ATTTTVTAPP GGTDSVIIRE PPNPTVTTTE YWSQSFATTT TVTAPPGGTD
760 770 780 790 800
SVIIREPPNP TVTTTEYWSQ SFATTTTVTA PPGGTDSVII REPPNPTVTT
810 820 830 840 850
TEYWSQSYAT TTTVTAPPGG TDTVIIREPP NYTVTTTEYW SQSYATTTTV
860 870 880 890 900
TGPPGGTDTV IIREPPNPTV TTTEYWSQSY ATTTTVTSPP GGTDIVIIRE
910 920 930 940 950
PPNPTVTTTE YWSQSYATTT TVTAPPGGTD SVIIREPPNP TVTTTEYWSQ
960 970 980 990 1000
SYATTTTVTA PPGGTDSVII REPPNPTVTT TEYWSQSYAT TTTVTAPPGG
1010 1020 1030 1040 1050
TDSVIIREPP NPTVTTTEYW SQSFATTTTV TAPPGGTDSV IIREPPNPTV
1060 1070 1080 1090 1100
TTTEYWSQSY ATTTTVTAPP GGTDTVIIRE PPNYTVTTTE YWSQSYATTT
1110 1120 1130 1140 1150
TVTGPPGGTD TVIIREPPNP TVTTTEYWSQ SYATTTTVTS PPGGTDIVII
1160 1170 1180 1190 1200
REPPNPTVTT TEYWSQSFAT TTTVTAPPGG TDSVIIREPP NPTVTTTEYW
1210 1220 1230 1240 1250
SQSYATTTTV TAPPGGTDSV IIREPPNPTV TTTEYWSQSY ATTTTVTAPP
1260 1270 1280 1290 1300
GGTDTVIIRE PPNPTVTTTE YWSQSYATTT TVTAPPGGTD SVIIREPPNP
1310 1320 1330 1340 1350
TVTTTEYWSQ SYATTTTVTA PPGGTDTVII REPPNYTVTT TEYWSQSYAT
1360 1370 1380 1390 1400
TTTVTAPPGG TDTVIIREPP SPTVTTTEYW SQSYATTTTV TAPPGGTATV
1410 1420 1430 1440 1450
IIKEPPNYTV TTTEYWSQSY ATTTTITAPP GGTDTVIIRE PPNYTVTTTE
1460 1470 1480 1490 1500
YWSQSYATTT TVTAPPGGTD TVIIREPPNY TVTTTEYWSQ SYATTTTVTG
1510 1520 1530 1540 1550
PPGGTDTVII REPPSPTVTT TEYWSQSYAT TTTVTAPPGG TATVIIREPP
1560 1570 1580 1590 1600
NYTVTTTEYW SQSYATTTTI TAPPGGTDTV IIREPPNYTV TTTEYWSQSY
1610 1620 1630 1640 1650
ATTTTVTGPP GGTDTVIIRE PPNYTVTTTE YWSQSYATTT TVTGPPGGTD
1660 1670 1680 1690 1700
TVIIREPPNY TVTTTEYWSQ SYATTTTVTG PPGGTDTVII REPPNPTVTT
1710 1720 1730 1740 1750
TEYWSQSYAT TLTITAPPGG TNSVIIRVHS STNDESSEST FSTLSVPSFS
1760 1770 1780 1790 1800
GSISIVSTVS RPHYVNSTVT HLPSSSSKPV DIPSSDVVTS TNDNSLTSLT
1810 1820 1830 1840 1850
GSENGKTSVA ISTTFCDDEN GCQTSIPQGS VVRTTATTTA TTTTIIGDNN
1860 1870 1880 1890 1900
GSGKSKSGEL SSTGSVTTNT ATPDVPSTKV PSNPGAPGTG VPPPLAPSTE
1910 1920 1930 1940 1950
TQTTNNVPGS PNIPATGTTD IIRESTTVSH TVTGNGNTGV PMNPNPVLTT
1960 1970 1980 1990 2000
STSLTGATNS ATNPSHETSV NTGSGGSTNI VTPPSSATAT VVIPGTDNGA
2010 2020 2030 2040 2050
TTKGQDTAGG GNSNGSTATT NIQGGNNEPG NQPGTNTTGE PVGTTDTQSV
2060 2070 2080 2090 2100
ESISQPTTLS QQTTSSLIST PLASTFDGSG SIVQHSGWLY VLLTAISIFF
Length:2,100
Mass (Da):220,888
Last modified:January 18, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1AEC27572CA0E400
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti169T → A in allele ALS4-2. 1 Publication1
Natural varianti484Y → F in allele ALS4-2. 1 Publication1
Natural varianti520Y → F in allele ALS4-2. 1 Publication1
Natural varianti592Y → F in allele ALS4-2. 1 Publication1
Natural varianti664F → Y in allele ALS4-2. 1 Publication1
Natural varianti736 – 742FATTTTV → YVTTSTI in allele ALS4-2. 1 Publication7
Natural varianti751S → T in allele ALS4-2. 1 Publication1
Natural varianti760P → Y in allele ALS4-2. 1 Publication1
Natural varianti772F → Y in allele ALS4-2. 1 Publication1
Natural varianti852G → A in allele ALS4-2. 1 Publication1
Natural varianti867N → S in allele ALS4-2. 1 Publication1
Natural varianti888S → A in allele ALS4-2. 1 Publication1
Natural varianti895 – 1110Missing in allele ALS4-2. 1 PublicationAdd BLAST216
Natural varianti1168F → Y in allele ALS4-2. 1 Publication1
Natural varianti1255T → S in allele ALS4-2. 1 Publication1
Natural varianti1336 – 1695Missing in allele ALS4-2. 1 PublicationAdd BLAST360
Natural varianti1789T → P in allele ALS4-2. 1 Publication1
Natural varianti1806K → E in allele ALS4-2. 1 Publication1
Natural varianti1837T → P in allele ALS4-2. 1 Publication1
Natural varianti1842T → P in allele ALS4-2. 1 Publication1
Natural varianti1844T → P in allele ALS4-2. 1 Publication1
Natural varianti1947V → A in allele ALS4-2. 1 Publication1
Natural varianti1969S → G in allele ALS4-2. 1 Publication1
Natural varianti1975G → R in allele ALS4-2. 1 Publication1
Natural varianti2011Missing in allele ALS4-2. 1 Publication1
Natural varianti2016S → F in allele ALS4-2. 1 Publication1
Natural varianti2022I → T in allele ALS4-2. 1 Publication1
Natural varianti2046D → G in allele ALS4-2. 1 Publication1
Natural varianti2053I → T in allele ALS4-2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF272027 mRNA Translation: AAG25054.1
CP017628 Genomic DNA Translation: AOW30333.1

NCBI Reference Sequences

More...
RefSeqi
XP_710425.2, XM_705333.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
3647972

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cal:CAALFM_C604130CA

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF272027 mRNA Translation: AAG25054.1
CP017628 Genomic DNA Translation: AOW30333.1
RefSeqiXP_710425.2, XM_705333.2

3D structure databases

SMRiA0A1D8PQB9
ModBaseiSearch...

Genome annotation databases

GeneIDi3647972
KEGGical:CAALFM_C604130CA

Organism-specific databases

CGDiCAL0000174423, ALS4
EuPathDBiFungiDB:C6_04130C_A

Phylogenomic databases

KOiK22493
OrthoDBi1428896at2759

Family and domain databases

Gene3Di2.60.40.1280, 1 hit
2.60.40.2430, 1 hit
InterProiView protein in InterPro
IPR008966, Adhesion_dom_sf
IPR008440, Agglutinin-like_ALS_rpt
IPR024672, Agglutinin-like_N
IPR043063, Agglutinin-like_N_N2
IPR033504, ALS
IPR011252, Fibrogen-bd_dom1
PANTHERiPTHR33793, PTHR33793, 7 hits
PfamiView protein in Pfam
PF05792, Candida_ALS, 38 hits
PF11766, Candida_ALS_N, 1 hit
SMARTiView protein in SMART
SM01056, Candida_ALS_N, 1 hit
SUPFAMiSSF49401, SSF49401, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiALS4_CANAL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1D8PQB9
Secondary accession number(s): Q9HFX4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2017
Last sequence update: January 18, 2017
Last modified: December 11, 2019
This is version 19 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Candida albicans
    Candida albicans: entries and gene names
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