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Entry version 31 (29 Sep 2021)
Sequence version 1 (18 Jan 2017)
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Protein
Submitted name:

Myosin 1

Gene

MYO1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi191 – 198ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotation, Motor protein, MyosinPROSITE-ProRule annotationARBA annotation
LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Myosin 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MYO1Imported
Ordered Locus Names:orf19.6294Imported
ORF Names:CAALFM_C501650CAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri237561 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000559 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Candida Genome Database

More...
CGDi
CAL0000200546, MYO1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:C5_01650C_A

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
5476.C4YR52

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A1D8PN92

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini77 – 786Myosin motorInterPro annotationAdd BLAST710

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni143 – 165DisorderedSequence analysisAdd BLAST23
Regioni666 – 688Actin-bindingPROSITE-ProRule annotationAdd BLAST23
Regioni1378 – 1414DisorderedSequence analysisAdd BLAST37

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili652 – 672Sequence analysisAdd BLAST21
Coiled coili858 – 906Sequence analysisAdd BLAST49
Coiled coili921 – 962Sequence analysisAdd BLAST42
Coiled coili970 – 1004Sequence analysisAdd BLAST35
Coiled coili1009 – 1043Sequence analysisAdd BLAST35
Coiled coili1048 – 1145Sequence analysisAdd BLAST98
Coiled coili1149 – 1225Sequence analysisAdd BLAST77
Coiled coili1253 – 1273Sequence analysisAdd BLAST21
Coiled coili1303 – 1337Sequence analysisAdd BLAST35
Coiled coili1350 – 1377Sequence analysisAdd BLAST28
Coiled coili1453 – 1506Sequence analysisAdd BLAST54
Coiled coili1570 – 1604Sequence analysisAdd BLAST35
Coiled coili1611 – 1638Sequence analysisAdd BLAST28
Coiled coili1646 – 1701Sequence analysisAdd BLAST56
Coiled coili1716 – 1743Sequence analysisAdd BLAST28
Coiled coili1751 – 1782Sequence analysisAdd BLAST32
Coiled coili1848 – 1889Sequence analysisAdd BLAST42
Coiled coili1909 – 1938Sequence analysisAdd BLAST30

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi143 – 164Polar residuesSequence analysisAdd BLAST22
Compositional biasi1379 – 1396Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi1397 – 1414Polar residuesSequence analysisAdd BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0161, Eukaryota

Identification of Orthologs from Complete Genome Data

More...
OMAi
NAHNEAQ

Database of Orthologous Groups

More...
OrthoDBi
47111at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.850.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000048, IQ_motif_EF-hand-BS
IPR036961, Kinesin_motor_dom_sf
IPR001609, Myosin_head_motor_dom
IPR027417, P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00063, Myosin_head, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00193, MYOSINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00242, MYSc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50096, IQ, 1 hit
PS51456, MYOSIN_MOTOR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1D8PN92-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVTSSTANDN NNEDPIISKN WVWVPNQQDL FTKGYITDYL PDGKCKVNVV
60 70 80 90 100
KGQESSHDST IIVDQDKLEN CNPVKFNKCE DMAELTHLNE PSVVYNLYLR
110 120 130 140 150
YLDDLIYTYS GLFLVAINPY KSLPIYNQSI LMKYHQYNNV TTNKNDYKSK
160 170 180 190 200
NASNSNNNNK GQSPPHIFAV AESTFRNLLS NKKDQSILVT GESGAGKTEN
210 220 230 240 250
TKKIIQYLSS ITSGSHTNKV DHNNSIDTKI LQANPILESF GNAKTIKNNN
260 270 280 290 300
SSRFGKFIQI YFSNTGEISG ANINYYLLEK SRVISQSNQE RNYHIFYQFL
310 320 330 340 350
KGYENLPSLG LNKDMSTYNY LSGGKLTINN VDDFKEFNLL VEAFKIMGFT
360 370 380 390 400
TNKMNFIYQV LAIILHLGNI TFTSWKSEQA NFTNDSPIDR ICELLAVDKD
410 420 430 440 450
LFVQNLLRPK VKAGREFITK SKKPNEVKFA IDAFAKYLYE KLFQFIITKI
460 470 480 490 500
NEKLDQSHNG DDNTANNNND NNFFIGVLDI AGFEIFDINS FEQLCINYTN
510 520 530 540 550
EKLQQFFNHH SFILEQSEYL RENINWEFID FGQDLQPTID LIETKQPMGI
560 570 580 590 600
LKLLDEECLM PKSSDASFME KLSKNFSNTH KKFSENKFKN GFIIHHYAGK
610 620 630 640 650
VEYNVENWLQ KNTDPISESI LNLLPDSQNE LIADMFINDP HINRPQTNGG
660 670 680 690 700
GNSKLKTASQ KHKDQLKTLM DQLESTEPHF VRCILPNLEK RANKFDKNLV
710 720 730 740 750
LGQLRCNGVL EGIRITRAGY PNRMMFDEFI QRYSIICDNE LSSPQNKTNC
760 770 780 790 800
EIILKFVKLN PEDFKVGLTK IFFKNGILGK LEIIRDLALK NIFTDLQKVI
810 820 830 840 850
RGNLTRLVLK QKIKEIQSAQ IISRTMVTLD EIKSNSPWMR LFFHVKPLLE
860 870 880 890 900
DSAKVLDSKK LQENLQTLTV KLKDSEKLTK GLETDNEKLR EQMNNLQDEM
910 920 930 940 950
INITSIAKEK DDKLSQLRLT ENKSKHRIET LEIKLKDFEK QNQDLINEHE
960 970 980 990 1000
KLTRRSLELH DKHNAKVEEL NSLNKLHDSA QSELSNLKQQ LKEITKLKQD
1010 1020 1030 1040 1050
HSKELLKFKQ MHDKSIEDLN EKVSRLENLN KKLQADLNSS KDVISSEHGK
1060 1070 1080 1090 1100
LQNEIMKLKE LCSDYERKQK DSQRTIDSLQ IQLKKDEDYK SRYESKIEEA
1110 1120 1130 1140 1150
REKVTLLKGK VEKKSQEIDQ YKSEIKKLKA ELASSNTKIT QLDQSTKELS
1160 1170 1180 1190 1200
SLKSNESKYV AEIESAKQQL SKKIEEYSSI EADYNRLQTE LKQMKQTNTE
1210 1220 1230 1240 1250
YSTRITELST KLNQVTEEAK SKEIEKENQP PNPQFMEEFT HMKLKVNEQT
1260 1270 1280 1290 1300
ASLRKEKFEN KKLSEELQML KERIMNGSLT SMDLTPKRRS LAIGDKSMIT
1310 1320 1330 1340 1350
NTVDSFNKEI ENLKFQLQQE QGNFQRAENY AIELQKKLNK LLTTRGLNTN
1360 1370 1380 1390 1400
TDYEKKYNDS QKRITQLETK IGRLLANSGG DYEDHHLDDN DDDWESRSSN
1410 1420 1430 1440 1450
GGSGGGSTSS SARNSLVKSE SITAFHNMRG VSQDYIQIYQ DITKTLKSTR
1460 1470 1480 1490 1500
EELNGSKTEI LRLKALLRES EDELYQVKQE NYKTSVHDYE QDLAQLKVKH
1510 1520 1530 1540 1550
ETLLSRNKDI NESLEIYKKR SDEYYKKLEL AESAIAISKR HEEQATKEMK
1560 1570 1580 1590 1600
ESRSQLLLVR EELRTTQILI KDFRIKVGNL EATIEEKNHQ LDANKEEIKQ
1610 1620 1630 1640 1650
IQDKLNYHLK NFENKELNEK LKEEIKNLNR DLDFKTDIET KLIKENKKLQ
1660 1670 1680 1690 1700
LDYEDVLLVK NNLQNEVEEL ILQEEKLQNK IDELTNNNRQ LENEKLINER
1710 1720 1730 1740 1750
KIVNCTKQIS GLKELVDEIS IERDKLLKDK ETLQNDLQIM TNKFDSTTTE
1760 1770 1780 1790 1800
LKQAHGELNF LKKHLENQRE DSEAIKTELN QSKMSTSFDI RDQQKLRNEL
1810 1820 1830 1840 1850
LVTKEENFSL VKTNKELNLK VSDLEEKLYS NEQLKYWESK VDTLSKALDG
1860 1870 1880 1890 1900
ALNEKHEADK TIKNLQRSIK QLEIRVENES QLSKRYNDEN FDYQNKINHY
1910 1920 1930 1940
KSTIDIIHNE NIEKDLQLKS IQRENIEMKE SMLMLQKEVL ELRERLQV
Length:1,948
Mass (Da):226,692
Last modified:January 18, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8E49473AB44A439D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP017627 Genomic DNA Translation: AOW29597.1

NCBI Reference Sequences

More...
RefSeqi
XP_711151.2, XM_706059.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
3647248

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cal:CAALFM_C501650CA

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017627 Genomic DNA Translation: AOW29597.1
RefSeqiXP_711151.2, XM_706059.2

3D structure databases

SMRiA0A1D8PN92
ModBaseiSearch...

Protein-protein interaction databases

STRINGi5476.C4YR52

Genome annotation databases

GeneIDi3647248
KEGGical:CAALFM_C501650CA

Organism-specific databases

CGDiCAL0000200546, MYO1
VEuPathDBiFungiDB:C5_01650C_A

Phylogenomic databases

eggNOGiKOG0161, Eukaryota
OMAiNAHNEAQ
OrthoDBi47111at2759

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR000048, IQ_motif_EF-hand-BS
IPR036961, Kinesin_motor_dom_sf
IPR001609, Myosin_head_motor_dom
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF00063, Myosin_head, 1 hit
PRINTSiPR00193, MYOSINHEAVY
SMARTiView protein in SMART
SM00242, MYSc, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50096, IQ, 1 hit
PS51456, MYOSIN_MOTOR, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1D8PN92_CANAL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1D8PN92
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 18, 2017
Last sequence update: January 18, 2017
Last modified: September 29, 2021
This is version 31 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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