UniProtKB - A0A1D5RLS1 (A0A1D5RLS1_MOUSE)
Protein
Submitted name:
Epidermal growth factor receptor substrate 15-like 1
Gene
Eps15l1
Organism
Mus musculus (Mouse)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Calcium bindingi | 172 – 183 | PROSITE-ProRule annotationAdd BLAST | 12 |
GO - Molecular functioni
- calcium ion binding Source: InterPro
Keywordsi
Ligand | CalciumPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Epidermal growth factor receptor substrate 15-like 1Imported |
Gene namesi | Name:Eps15l1Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:104582, Eps15l1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 15 – 104 | EHInterPro annotationAdd BLAST | 90 | |
Domaini | 48 – 83 | EF-handInterPro annotationAdd BLAST | 36 | |
Domaini | 127 – 215 | EHInterPro annotationAdd BLAST | 89 | |
Domaini | 159 – 194 | EF-handInterPro annotationAdd BLAST | 36 | |
Domaini | 272 – 307 | EF-handInterPro annotationAdd BLAST | 36 | |
Domaini | 273 – 363 | EHInterPro annotationAdd BLAST | 91 | |
Domaini | 308 – 341 | EF-handInterPro annotationAdd BLAST | 34 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 229 – 260 | DisorderedSequence analysisAdd BLAST | 32 | |
Regioni | 476 – 495 | DisorderedSequence analysisAdd BLAST | 20 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 384 – 467 | Sequence analysisAdd BLAST | 84 | |
Coiled coili | 531 – 551 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 235 – 258 | PolarSequence analysisAdd BLAST | 24 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000155438 |
OrthoDBi | 597979at2759 |
Family and domain databases
CDDi | cd00052, EH, 3 hits |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom IPR000261, EH_dom |
Pfami | View protein in Pfam PF12763, EF-hand_4, 3 hits |
SMARTi | View protein in SMART SM00054, EFh, 3 hits SM00027, EH, 3 hits |
SUPFAMi | SSF47473, SSF47473, 3 hits |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 1 hit PS50222, EF_HAND_2, 4 hits PS50031, EH, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
A0A1D5RLS1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAPLVPLSQ QIPGGNPLYE SYYKQVDPAY TGRVGASEAA LFLKKSGLSD
60 70 80 90 100
IILGKIWDLA DPEGKGFLDK QGFYVALRLV ACAQSGHEVT LSSLSLTMPP
110 120 130 140 150
PKFHDTSSPL MATQSSAETH WAVRVEEKAK FDGIFESLLP VNGLLSGDKV
160 170 180 190 200
KPVLMNSKLP LDVLGRVWDL SDIDKDGHLD RDEFAVAMHL VYRALEKEPV
210 220 230 240 250
PSILPPPLIP PSKRKKTVFA GAVPVLPASP PPKDSLRSTP SHGSVSSLNS
260 270 280 290 300
TGSLSPKHSV KQPPVAWVVP VADKMRFDEI FLKTDLDLDG YVSGQEVKEI
310 320 330 340 350
FMHSGLTQNL LAHIWALADT RQTGKLSKEQ FALAMYFIQQ KVSKGIDPPQ
360 370 380 390 400
VLSPDMVPPS ERGTPIPDSS STLASGEFTG VKELDDISQE IAQLQREKYS
410 420 430 440 450
LEQDIREKEE AIRQKTSEVQ ELQNDLDRET SSLQELEAQK QDAQDRLDEM
460 470 480 490 500
DQQKAKLRDM LSDVRQKCQD ETQTISSLKT QIQSQESDLK SQEDDLNRAK
510 520 530 540 550
SELNRLQQEE TQLEQSIQAG RAQLETILRS LKCTQDDINQ ARSKLSQLQE
560 570 580 590
SHLEAHRSLE QYDQVPDGVS GTSLPDLATL NEGILLAERG GFGAMVKVE
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ60902 | EP15R_MOUSE | Epidermal growth factor receptor su... | Eps15l1 Eps15-rs, Eps15R | 907 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC113182 Genomic DNA No translation available. |
RefSeqi | NP_001116304.1, NM_001122832.1 |
Genome annotation databases
Ensembli | ENSMUST00000212590; ENSMUSP00000148484; ENSMUSG00000006276 |
GeneIDi | 13859 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC113182 Genomic DNA No translation available. |
RefSeqi | NP_001116304.1, NM_001122832.1 |
3D structure databases
SMRi | A0A1D5RLS1 |
ModBasei | Search... |
Proteomic databases
jPOSTi | A0A1D5RLS1 |
Protocols and materials databases
Antibodypediai | 14142, 193 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000212590; ENSMUSP00000148484; ENSMUSG00000006276 |
GeneIDi | 13859 |
Organism-specific databases
CTDi | 58513 |
MGIi | MGI:104582, Eps15l1 |
Phylogenomic databases
GeneTreei | ENSGT00940000155438 |
OrthoDBi | 597979at2759 |
Miscellaneous databases
BioGRID-ORCSi | 13859, 4 hits in 17 CRISPR screens |
ChiTaRSi | Eps15l1, mouse |
SOURCEi | Search... |
Gene expression databases
ExpressionAtlasi | A0A1D5RLS1, baseline and differential |
Family and domain databases
CDDi | cd00052, EH, 3 hits |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom IPR000261, EH_dom |
Pfami | View protein in Pfam PF12763, EF-hand_4, 3 hits |
SMARTi | View protein in SMART SM00054, EFh, 3 hits SM00027, EH, 3 hits |
SUPFAMi | SSF47473, SSF47473, 3 hits |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 1 hit PS50222, EF_HAND_2, 4 hits PS50031, EH, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A1D5RLS1_MOUSE | |
Accessioni | A0A1D5RLS1Primary (citable) accession number: A0A1D5RLS1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 30, 2016 |
Last sequence update: | November 30, 2016 | |
Last modified: | December 2, 2020 | |
This is version 25 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |