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Entry version 30 (02 Jun 2021)
Sequence version 1 (30 Nov 2016)
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Protein
Submitted name:

Predicted gene 11639

Gene

Gm11639

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi5470 – 5481PROSITE-ProRule annotationAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalciumPROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Predicted gene 11639Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Gm11639Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3651790, Gm11639

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A0A1D5RLM8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
314902

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A1D5RLM8, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
A0A1D5RLM8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A1D5RLM8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini199 – 234EF-handInterPro annotationAdd BLAST36
Domaini236 – 271EF-handInterPro annotationAdd BLAST36
Domaini701 – 717EF-handInterPro annotationAdd BLAST17
Domaini718 – 753EF-handInterPro annotationAdd BLAST36
Domaini863 – 897EF-handInterPro annotationAdd BLAST35
Domaini1035 – 1053EF-handInterPro annotationAdd BLAST19
Domaini1054 – 1089EF-handInterPro annotationAdd BLAST36
Domaini1126 – 1161EF-handInterPro annotationAdd BLAST36
Domaini1233 – 1268EF-handInterPro annotationAdd BLAST36
Domaini1412 – 1447EF-handInterPro annotationAdd BLAST36
Domaini1556 – 1591EF-handInterPro annotationAdd BLAST36
Domaini1620 – 1655EF-handInterPro annotationAdd BLAST36
Domaini1837 – 1862EF-handInterPro annotationAdd BLAST26
Domaini2186 – 2202EF-handInterPro annotationAdd BLAST17
Domaini2294 – 2311EF-handInterPro annotationAdd BLAST18
Domaini2365 – 2400EF-handInterPro annotationAdd BLAST36
Domaini2736 – 2751EF-handInterPro annotationAdd BLAST16
Domaini2771 – 2788EF-handInterPro annotationAdd BLAST18
Domaini2789 – 2824EF-handInterPro annotationAdd BLAST36
Domaini2894 – 2929EF-handInterPro annotationAdd BLAST36
Domaini2947 – 2982EF-handInterPro annotationAdd BLAST36
Domaini3000 – 3035EF-handInterPro annotationAdd BLAST36
Domaini3143 – 3158EF-handInterPro annotationAdd BLAST16
Domaini3248 – 3264EF-handInterPro annotationAdd BLAST17
Domaini3318 – 3353EF-handInterPro annotationAdd BLAST36
Domaini3354 – 3370EF-handInterPro annotationAdd BLAST17
Domaini3371 – 3406EF-handInterPro annotationAdd BLAST36
Domaini3424 – 3459EF-handInterPro annotationAdd BLAST36
Domaini3460 – 3476EF-handInterPro annotationAdd BLAST17
Domaini3521 – 3556EF-handInterPro annotationAdd BLAST36
Domaini4189 – 4206EF-handInterPro annotationAdd BLAST18
Domaini4948 – 4983EF-handInterPro annotationAdd BLAST36
Domaini5266 – 5301EF-handInterPro annotationAdd BLAST36
Domaini5319 – 5354EF-handInterPro annotationAdd BLAST36
Domaini5421 – 5456EF-handInterPro annotationAdd BLAST36
Domaini5467 – 5492EF-handInterPro annotationAdd BLAST26

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni106 – 137DisorderedSequence analysisAdd BLAST32
Regioni315 – 389DisorderedSequence analysisAdd BLAST75
Regioni401 – 681DisorderedSequence analysisAdd BLAST281
Regioni5770 – 5808DisorderedSequence analysisAdd BLAST39

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1869 – 1889Sequence analysisAdd BLAST21
Coiled coili2880 – 2900Sequence analysisAdd BLAST21
Coiled coili3039 – 3059Sequence analysisAdd BLAST21
Coiled coili3463 – 3483Sequence analysisAdd BLAST21
Coiled coili3807 – 3827Sequence analysisAdd BLAST21
Coiled coili3877 – 3909Sequence analysisAdd BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi325 – 347Polar residuesSequence analysisAdd BLAST23
Compositional biasi363 – 379Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi418 – 681Basic and acidic residuesSequence analysisAdd BLAST264
Compositional biasi5770 – 5789Polar residuesSequence analysisAdd BLAST20

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000004027

Identification of Orthologs from Complete Genome Data

More...
OMAi
EKTNFMP

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13833, EF-hand_8, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00054, EFh, 13 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47473, SSF47473, 34 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00018, EF_HAND_1, 1 hit
PS50222, EF_HAND_2, 36 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A1D5RLM8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKTHLICKT EESIDVSIHG SDTITTKLIS RNIETKKYCK ISKTTGKKIS
60 70 80 90 100
SESKGFIPEY KKIYETSLFV YREEKPTEFS GSKKLRRKKS VQVQLHSKRT
110 120 130 140 150
EIATPSLKVS KEKITKKESP SKLPSHKPSL TQRTASTAGR KVIPSNLSLT
160 170 180 190 200
LYEQVPEEFL KHQELNALSK GCLIFSKVRS GKIYVNDLPV VLHALKISTS
210 220 230 240 250
DSEVRQALKA VSIDVNGILD FTEFLKVMND TSPSSSQDPE FQNALKIFSK
260 270 280 290 300
VKSGRVATTD VAAVLESMDI SVNPEMIKDV IQHAYEDNYH TMDIGDIIFT
310 320 330 340 350
LDELQRQYED VSVMDEATSG KRASTIPGHH PQQKKSSLLS RMPEPSTPKN
360 370 380 390 400
QTVPPQPHPS KTTGKQDEAE LKLSKRSSET RRLSSGIISD SVGLQESQIK
410 420 430 440 450
IHDSKSKSPS LKSTPSLSKL PDRRDSSLKK SPDRSDSSLK KSPDRRDSSL
460 470 480 490 500
KKSPDRRDSS LKKSPDRSDS SLKKSLDKSD SSLKKSLDKS DSSLKKSLDK
510 520 530 540 550
SDSSLKKLLD KSDTSLNKLL DKSDTSLKKL LDKSDSSLKK SPDRSDSSLK
560 570 580 590 600
KSPDRSDSSL KKLSDRRDSS LKKSLDRSDS SLKKSPDRSD SSLKKLSDRR
610 620 630 640 650
DSSLKKSLDK SDSSLKKSLD KSDSSLKKSP DRSDSSLKKL SDRRDSSLKK
660 670 680 690 700
SPDRSDSSLK KSPDRRDSSL KKSLDKSDSS LKKSLDKKNA YEVILKLQED
710 720 730 740 750
YISPEELQTI LPSVGVTLSD EDFQRIVPEL TQTESGMVNL DDFITAVSKE
760 770 780 790 800
HNFPDYDALK NAIEGISKIQ DEYVEYEDLD TCLQNFGVYL PKSERQRIKE
810 820 830 840 850
LIQVDDTKQV NIKKFIDAML KNTHPFSEDI FLPAAIENLQ NFCGDQMDVA
860 870 880 890 900
QLWKTLSSLD SSLKEKEFLD AVKLATVDGD KVQLEDFSKV VKDMHDSVRL
910 920 930 940 950
KELQEIVSAL DSLEGEKIPG KNVDDFLKSL GITSFKDELE EILQSEIVSD
960 970 980 990 1000
DNMLSVKDCM EALKDTSKFS NFTALKEAIE MLDSVKGSYW SDKERFLEGL
1010 1020 1030 1040 1050
EDLEGLKKEV LSSNLVLPTV SEIKEVAGIL SQVEDGKITI PDLERALKYL
1060 1070 1080 1090 1100
NLNISEEDFK EVLKHCDISD EMYVDLKDFL VKLRDIPSFK DSIVTQLLLA
1110 1120 1130 1140 1150
TPQVLEKDLI NVSDLKKLLT NNELHSAKAI LTEVLKHVPE DEEGKITIEE
1160 1170 1180 1190 1200
FVSTLSDILR TLKSEREKEI LHNTNFDLNN VNVTSEIKQS LDALGIHITG
1210 1220 1230 1240 1250
SDIQRAMENM ASSGEVITLK DIIKELANSD VFSECQRIED IHRIIDVIGD
1260 1270 1280 1290 1300
GKMDVKDFLS ALNNFTRPLE EEGQSDVSQS PEMNEKEAIL RNTINYLTGV
1310 1320 1330 1340 1350
SAMTRFKSLL KGVQTFDNIR GNKMPVDELV SNLMSTGMPI SQSTMQELLR
1360 1370 1380 1390 1400
QASVDENEEV SLKQILENLA TRNPDPVLED IENALNSVKL MTSDKIQVAN
1410 1420 1430 1440 1450
LKDALKDLNI HLSPEELQQV EEALNVDENG EVSQRAVLLA LKSNKRLKDF
1460 1470 1480 1490 1500
REVNELAKAL DKITSEKIRT DDLIHVSKGL GFGVPDKELQ DLDETVSIDE
1510 1520 1530 1540 1550
EGNVDLKEWL TKLKGTPHFN KSSKIQTPMK TLASIRKNET NYDDLPFILN
1560 1570 1580 1590 1600
SMGVALPQDI IEAALRNMAH RENGKLNLDE FLNQLIKVQL SSIPESRVSL
1610 1620 1630 1640 1650
EEKIDASSVD DILKSMDITL TDQEKKALFE HLPVPGDEGI DMETLIGAVK
1660 1670 1680 1690 1700
MLKEKIDVTN LSNFLDDMGV ELSKEEQSDL INHLPVSAEG KVSHLQLVDT
1710 1720 1730 1740 1750
IKNLKSGKAD IEKLEGILGK MGLALTSLEF QNLQENLPID TDGKVDLGIL
1760 1770 1780 1790 1800
LDQVKLLKKE EGKAYDTNLD TILEKMGMDF SDKISEESEK HMEVQLSKPL
1810 1820 1830 1840 1850
MEFPHISGKT IDFRDLDTVL EKMDIELTEG EDEELKRHFS DDAKGTIDLD
1860 1870 1880 1890 1900
SLVNVLQVTT GGEIDVSDME NVIKDVERER TSREQLEREK SFPSHVDVRN
1910 1920 1930 1940 1950
LDSLLGSMAF KVIPEEFPES ASKSAVHRRD VDTESISKHR ESIPEIQEPS
1960 1970 1980 1990 2000
ELMDDLSIEG RKIDVSSLDE ILGKMQIHLS EKELDKLTEG LPAGEKIDLI
2010 2020 2030 2040 2050
DIKSILHLKS ISGESINLKS ISTDDIREFY QKKLAESVED FEGKSIDVHE
2060 2070 2080 2090 2100
LESVLQTINV KLSESQMSGL KENLQVDESG KTSFRSLLDS ITEIVAKELG
2110 2120 2130 2140 2150
IEDEKNVPED VELEDMEKDK LQLLKSQLPD EWIPDPQNLD IFLQRVGINL
2160 2170 2180 2190 2200
EEQEIGDLLQ TLPVGVHGEV EKETFLEKMA SFTGKKIHSS EMKEVLEDMG
2210 2220 2230 2240 2250
IDITDEGIRK LKEVLPFDAL DHTFQNRMLD VVQCINEGEV KLGNVESVLE
2260 2270 2280 2290 2300
NLGVKLISKE QESLMRILLS EEETHDEKIP LSQLILAVTK VTGGQVNIKD
2310 2320 2330 2340 2350
IKSALEKMGI ELTENECSQL ESLLPVNANG KVYKKRLLET AVTSKCGLVD
2360 2370 2380 2390 2400
VANIDTVLQS MDMQFTEEEI DTFMEKVPID DNQKVEFKNL LDAIEDFTGK
2410 2420 2430 2440 2450
NIDANDVLTV LRDMGIEFTE QEEEALWDVL PIHEPGMVYE KRMLEEVKAM
2460 2470 2480 2490 2500
KGGVVKVSNL DTILESLGIE LTDKEHESLT EHLPLTADGK IHLGQVLETV
2510 2520 2530 2540 2550
EAITGGDIDV SDMGNVLNEM GITLTVKENK ELLEHLPITS KDKVHKNRIM
2560 2570 2580 2590 2600
DGLKSFNRGT ANINELNTVL QNMGWKLTNE EIKDLKQNLA ADVHGRVALK
2610 2620 2630 2640 2650
KLFKGLNTFT GPKVDMRALP DIVEEMGLEL TDKERVDLIT ELPVDESGKI
2660 2670 2680 2690 2700
YKKRLLSGVK SFKGGKIKQN KINAALENVG IKLTEKELDV LEANLRDDGN
2710 2720 2730 2740 2750
GKVNFHDVMK EVNTIIGEEE NVNDIKDILD SLGLNLTEKE FIELLKTLPV
2760 2770 2780 2790 2800
DADGNFYHNR LMNTVKSGKR GKISADKLDT MVKNMGMKLS DMEYKDMIKN
2810 2820 2830 2840 2850
VPVSDAGEIE MEKLVDAMEA FTGNKININD LQYILGSMGI ELTEKMLSDL
2860 2870 2880 2890 2900
LKILPVDNDE MVFQKRLMKE VKSLKGKVDV NNIDNILEDM EVKLTEAELK
2910 2920 2930 2940 2950
DLMETLPVDD NGKAELAELM DTVKTLTGEE TDVKDVKNVL EEMGINLTEK
2960 2970 2980 2990 3000
ELMKLLKKLP VNEDGKVYKN RLMNSLTSFK GGTISATKVD SLLGSMGMKL
3010 3020 3030 3040 3050
EEKELKDLMQ NLQTDADGNV PLKMVMDEVR KFSGNKINVK DLQNNLRDMG
3060 3070 3080 3090 3100
IELTEAECSE LKKTLPTDAA GNVYQNKVMD SLKSQKGGMV NLSDLDKVLR
3110 3120 3130 3140 3150
NMGLELTEKE RKTLTDNLII KADGKISLSK LLDTVKAVRG EAIDMDDVED
3160 3170 3180 3190 3200
IMEDLGIEFT DKELLRLMES LQADADRNTY HKRVMESLRT YKEGKIKTDK
3210 3220 3230 3240 3250
VDTFLKNIDM DVLETELKDL KQNLPASASG KIDIRTIINE ANAFTGEKID
3260 3270 3280 3290 3300
VSNLRNLLRN MGVEFTDPEY TRLLRMLPVD DNGMVHWNRV LKAVKFLRGG
3310 3320 3330 3340 3350
KIDVKSLGSF LGNMSIKLTE QEVEELVESL PVDANGKVDL VKVMDEAKAF
3360 3370 3380 3390 3400
IGEKIGIDEV KNVLENMGLE YKDQELSKLM ESLPFDEDGK IHQNKLLESL
3410 3420 3430 3440 3450
KSLKGGMIST SNLKSVMDNL GIKLHDNEFK DMIQSLPVGA NKKISLDALM
3460 3470 3480 3490 3500
KKLKSFTGDK VDVSDLRNIL KNLGLELTEK EQERLLKMLP VDDAGKIYYN
3510 3520 3530 3540 3550
RLLKGVKSFN DNVLKNLGVK LSEEEFAKLS EDLPVDSSGK VDLKKVMEII
3560 3570 3580 3590 3600
KATTGGEVDS KHVKSVLSKM GIELTDSEVS KLMENLSFDD DNKIFKNRLL
3610 3620 3630 3640 3650
ESVKSLQGGK VDINNLGTVL DNMGVKLSNL ELRDLKQNMQ VGVDEKISLQ
3660 3670 3680 3690 3700
TLMQKLKDYT GEKIEASDVP SVLENLGIEL TDKELEELMK TLPFNESGKL
3710 3720 3730 3740 3750
YNNRLLKDVK DLKMGKIKKD NLHTSLENMG FKLSMEEFAE VTENLETDEK
3760 3770 3780 3790 3800
GNADLQTVMG KVKSVTENIN VKNLENVLGN MGVKLTKTEL DDLLKNLPIG
3810 3820 3830 3840 3850
ADNKVPLKML QEELKDFTGE KIDLNDLKRE LKNMGIVLSD KELRRLLKNL
3860 3870 3880 3890 3900
PVDDDGKVFQ NRLLRNVKDS KRGKVNVNNL DTALEALNIR LTKEELDMVK
3910 3920 3930 3940 3950
DALEDGQKEV ELRKLVDQIE SVTGNEVEVT KVDKMLKEMG IELSDSEFLK
3960 3970 3980 3990 4000
LMNNVPVDDG KVYLKRLMDG MTIVKDGKVD SSKLSTLLGN MGVTITQRES
4010 4020 4030 4040 4050
DDLKKTLKLD ENHKAEVKRV INEAKVFTGQ KVDTNKLQSV LDRYGIKLNP
4060 4070 4080 4090 4100
EEVTKLLNSL PVDDDGKAFQ KRLLKGVTSL DEATVDVDKL DTFLESMGIE
4110 4120 4130 4140 4150
ITEKEFGDLT DTLTGTSDGK VKLNSVMENL TTILGDSVDI NDVGDILKDM
4160 4170 4180 4190 4200
KIEFTDKEYL NLIKHLSKKA SGKVYKKRIT DGLKHLKRGK IDVNNLSPFL
4210 4220 4230 4240 4250
ENMGLELSQN EYEDLAESLP VDETGKVDLK SIVPKMNEFT GEKISVGDLR
4260 4270 4280 4290 4300
NTVGQIGVEV NDKEYVDLLE RLPFDENKHV FQNRVLSSLR TSKGGRVDPN
4310 4320 4330 4340 4350
NLKTLLMNLD LKLKNKEIRD VIQKQTPGTN RSIPLKKVLA DVNSVIGEKI
4360 4370 4380 4390 4400
NVNDVKTFVE DAGITLTSKE QVELVTNLPV DDEGNIHESR LIDQLKSFKG
4410 4420 4430 4440 4450
GAVNVNIIEN VLENLKIKLS DEKVKEVSQS LPADASGMIS LQTMLKEVRK
4460 4470 4480 4490 4500
FTGGNIDAKV THRVLEGMGI QLSNRDINDL LKRLPIADDG KILKNVLLDH
4510 4520 4530 4540 4550
VKWHSGAKCH ISKLGGILED LGFNLEDEEI EDLTSRLPVE DEMVNMREMM
4560 4570 4580 4590 4600
ENVELLTGNK VDVDQIDQVL KTIGVELTPK ERWELMKTLP ITSDNKVYRN
4610 4620 4630 4640 4650
RLLDSLKTFH RGKGFTNKLE TIMENINYNV DEKDMKELQN YLKTDDIGRF
4660 4670 4680 4690 4700
SLNSLSNAAY LFSGPQINAS DIQPYLETVG IELTSSESQL LQSRVPADDD
4710 4720 4730 4740 4750
NMVFKNVLAD SMRTLRSGKV GVNNVYETIE FLGYPVEEEE VEEIIINVPS
4760 4770 4780 4790 4800
NSDKKVQLDL LLKEVDSYLG EEIDQSDVNK ILKNIGLILH LRENRVLMKS
4810 4820 4830 4840 4850
VPLDATGKVY KYKLMDTIKG LPDVYIDLKK IKTLMENMGY DLESNEYEDF
4860 4870 4880 4890 4900
MNYVPTNIYG LTRLKDIMEK GDVYTGEKID LGDLPEFLDD IGVELTEDKT
4910 4920 4930 4940 4950
MKLLGKLPTD GHGRLYKKRL IKELGTIKDL KIPTSKVETF FKKAVFQLNN
4960 4970 4980 4990 5000
KEMQTVIDKL PADRNGKVEY QVLMKEVRNV LGDMIHAGEV KSVLEDMGIK
5010 5020 5030 5040 5050
MTHKENVKFL KKLPVSADKT VYRKELLSGV KSFKGGEVYV QDVKNVLHNT
5060 5070 5080 5090 5100
GFELDKRELK DLRAHLTVTD RRRVSLDVLM DAAKIFTGEK VDIKYIKSAL
5110 5120 5130 5140 5150
ENMGIAITEK EELKLLKSLP VSKDGKIYKK RLLNSVAQIK GKKVQVSNIP
5160 5170 5180 5190 5200
LILKNAEFEL EKEDCEDLMQ LLHTDENKMV ELSVLLDKAK NFTGEKIDVG
5210 5220 5230 5240 5250
NLNNVLRKMG LMLSDNVYKE LQHALSVYTG GKIYKTRLLK CVKDLKGPRI
5260 5270 5280 5290 5300
KVKKVESLLE NMGIKVKGEE FEELIAQLPP EGNKTVDLNE LLDIVSYIKG
5310 5320 5330 5340 5350
EAIDMQNLYK FLANDGIELT EKEFKDLLSY LDFNGSGKVI VQSIIEGLKK
5360 5370 5380 5390 5400
LKPKEMAMLY KQMTSFRFRK DRASSQMAVS EIKATMKLKP LKAPVFHKRD
5410 5420 5430 5440 5450
KDLRGSFSDH LKHKESKLSP AQLEAFRNAY NFFTKDRTGC IDSHGLISTI
5460 5470 5480 5490 5500
AKLGMNLNTY DIYNELKCAD LDRDGKINFS DFINVLTDKK LFLKAVVPEK
5510 5520 5530 5540 5550
KICLDLANNP GILLFEILSK FVETSSLHRK DIIELVSYFR KRFQESHSEI
5560 5570 5580 5590 5600
MWSSYGRRGL KSEICSPPRS STAAFANSAR ISIMKERDLY KFLEALKRCN
5610 5620 5630 5640 5650
LRTDSPYSKI PVFPLFPDVD GTVMGKPFKD TQKIEMLRRK EPLTFFEDYF
5660 5670 5680 5690 5700
FNKRDWKTQA MNVKPLKSAS GYSDDILAID HLFKKKQHWT VTDAAAIKQH
5710 5720 5730 5740 5750
VKKATESYNL GIALDHRKEM LNLWKKIRGD LVGIESNNES FYNTFSTYTW
5760 5770 5780 5790 5800
SWNVCQELLS AKDLRLHDAS MNKSSPSNSG LSSPSDFSES DPETGRKRKR

KSSRGFRQ
Length:5,808
Mass (Da):654,206
Last modified:November 30, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA36AEAAF4CD31CE7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6RS26F6RS26_MOUSE
Predicted gene 11639
Gm11639
1,124Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000212287; ENSMUSP00000148433; ENSMUSG00000040838

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

SMRiA0A1D5RLM8
ModBaseiSearch...

Proteomic databases

EPDiA0A1D5RLM8
ProteomicsDBi314902

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
17742, 92 antibodies

Genome annotation databases

EnsembliENSMUST00000212287; ENSMUSP00000148433; ENSMUSG00000040838

Organism-specific databases

MGIiMGI:3651790, Gm11639

Phylogenomic databases

GeneTreeiENSGT00390000004027
OMAiEKTNFMP

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Gm11639, mouse
RNActiA0A1D5RLM8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

ExpressionAtlasiA0A1D5RLM8, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
PfamiView protein in Pfam
PF13833, EF-hand_8, 3 hits
SMARTiView protein in SMART
SM00054, EFh, 13 hits
SUPFAMiSSF47473, SSF47473, 34 hits
PROSITEiView protein in PROSITE
PS00018, EF_HAND_1, 1 hit
PS50222, EF_HAND_2, 36 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1D5RLM8_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1D5RLM8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2016
Last sequence update: November 30, 2016
Last modified: June 2, 2021
This is version 30 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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