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Entry version 20 (08 May 2019)
Sequence version 2 (10 Apr 2019)
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Protein
Submitted name:

Uncharacterized protein

Gene

COL5A1

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-GGA-1650814 Collagen biosynthesis and modifying enzymes

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:COL5A1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGallus gallus (Chicken)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9031 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000539 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9031.ENSGALP00000004011

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159211

Database of Orthologous Groups

More...
OrthoDBi
199083at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008160 Collagen
IPR013320 ConA-like_dom_sf
IPR000885 Fib_collagen_C
IPR001791 Laminin_G

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01410 COLFI, 1 hit
PF01391 Collagen, 5 hits

ProDom; a protein domain database

More...
ProDomi
View protein in ProDom or Entries sharing at least one domain
PD002078 Fib_collagen_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00038 COLFI, 1 hit
SM00210 TSPN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899 SSF49899, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51461 NC1_FIB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1D5PE74-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDTHTRWKRR SWIRNWQLHV ALVLLGAAAL GRAAEPADLL KVLDFHNLPD
60 70 80 90 100
GITRTTGFCT SRRSSKEADV AYRVTKDAQL SAPTKQLYPA SPFPEDFSIL
110 120 130 140 150
TTVKAKKGGQ SFLISIYNEQ GIQQIGVEMG RSPVFLYEDH TGKPGPEDYP
160 170 180 190 200
LFRGINLADG KWHRVAISVQ KKNVTLILDC KKKITKFLDR SDHPIIDVNG
210 220 230 240 250
IIVFGTRILD EEVFEGDIQQ LLIVADPRAA HDYCEHYSPD CDTAVPDAPQ
260 270 280 290 300
SQDPNQDEYY TDGEGEGDTY YYEYPYYEDV DEAVKPEAPT TKPAPPGVAA
310 320 330 340 350
GERPETKQDY PSPTPSPEAG NPSRQTKGAA PVDDPLVDEY NYETINEEYF
360 370 380 390 400
TPLPYEDINY NEEVDPQGGL TENAVEAELP TSTVITYNET DAAQGGDDLD
410 420 430 440 450
KDFTEETIKE YDGNYYYYDR TVSPDIGPGM PANQDTIYEG IGGPRGEKGQ
460 470 480 490 500
KGEPAIIEPG MLVEGPPGPE GPAGLPGPPG PTGPVGLMGD PGERGPPGRP
510 520 530 540 550
GLPGADGLPG PPGTMLMLPF RFSGGGDAGS KGPMVSAQEA QAQAILQQAR
560 570 580 590 600
LALRGPAGPM GLTGRPGPMG PPGSGGLKGE AGEMGPQGPR GIQGPPGPAG
610 620 630 640 650
KPGRRGRAGS DGARGMPGQT GPKGDRGFDG LAGLPGEKGN RGEPGPHGPP
660 670 680 690 700
GAPGEDGERG DDGEVGPRGL PGEPGPRGLL GPKGPPGPPG PPGVAGMDGQ
710 720 730 740 750
TGPKGNVGPQ GEPGPPGQQG NPGAQGLPGP QGPIGPPGEK GPLGKPGLPG
760 770 780 790 800
MPGADGPPGH PGKEGPPGEK GSQGPPGPQG PIGYPGPRGV KGADGVRGLK
810 820 830 840 850
GTKGEKGEDG FPGFKGDMGI KGDRGEIGPP GPRGEDGPEG PKGRSGPNGD
860 870 880 890 900
PGPLGPAGEK GKLGVPGLPG YPGRQGPKGS IGFPGFPGAN GEKGTRGTPG
910 920 930 940 950
KPGPRGQRGP TGPRGERGPR GSTGKPGPKG NSGGDGPPGP PGERGPPGPQ
960 970 980 990 1000
GPTGFPGPKG PPGPPGKDGL PGHPGQRGET GFQGKTGPPG PPGVVGPQGP
1010 1020 1030 1040 1050
TGETGPMGER GHPGPPGPPG EQGLPGLTGK EGTKGDPGPA GLPGKDGPPG
1060 1070 1080 1090 1100
LRGFPGERGL PGPIGSPGLK GNEGPPGPPG PAGSPGERGP AGSAGPIGLP
1110 1120 1130 1140 1150
GRPGPQGPPG PAGEKGAPGE KGPQGPAGRD GIQGPVGLPG PAGPVGPPGE
1160 1170 1180 1190 1200
DGDKGEIGEP GQKGSKGDKG EQGPPGPTGP QGPIGQPGPA GADGEPGPRG
1210 1220 1230 1240 1250
QQGLFGQKGD EGPRGFPGPP GPVGLQGLPG PPGEKGETGD VGQMGPPGPP
1260 1270 1280 1290 1300
GPRGPSGPPG ADGPQGPAGG IGNPGAVGEK GEPGESGEPG LPGEVGLPGP
1310 1320 1330 1340 1350
KGERGEKGEA GPSGAAGPPG PKGPPGDDGP KGSPGPVGFP GDPGPPGEPG
1360 1370 1380 1390 1400
PAGQDGPPGD KGDDGEPGQT GSPGPTGEPG PSGPPGKRGP PGPAGPEGRQ
1410 1420 1430 1440 1450
GEKGAKGEAG LEGPPGKTGP IGPQGAPGKP GPDGLRGIPG PVGEQGLPGS
1460 1470 1480 1490 1500
PGPDGPPGPL GPPGLPGLKG DSGPKGEKGH PGLIGLIGPP GEQGEKGDRG
1510 1520 1530 1540 1550
LPGPQGSAGP KGEQGITGPS GPIGPPGPPG LPGPPGPKGA KGSSGPTGPK
1560 1570 1580 1590 1600
GESGLPGPPG PPGPPGEVIQ PLPIQSSKRT RRNIDASQLV DDGNADNYMD
1610 1620 1630 1640 1650
YADGMEEIFG SLNSLKLEIE QMKHPLGTQH NPARTCKDLQ LCHPDFPDGE
1660 1670 1680 1690 1700
YWVDPNQGCS RDSFKVYCNF TAGGETCIFP DKKSEGARIT SWPKENPGSW
1710 1720 1730 1740 1750
FSEFKRGKLL SYVDSDGNPI GVVQMTFLRL LSASAHQNIT YNCYQSVAWH
1760 1770 1780 1790 1800
DATTDSYDKA IRFLGSNDEE MSYDNNPYIR AAFDGCAAKK GYQKTVLEIN
1810 1820 1830
TPKVEQVPIV DIMFNDFGEA SQKFGFEVGP ACFMG
Length:1,835
Mass (Da):184,185
Last modified:April 10, 2019 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7FBDE83857EFC472
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AADN05000150 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_990121.2, NM_204790.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSGALT00000059123; ENSGALP00000051075; ENSGALG00000002546

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
395568

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN05000150 Genomic DNA No translation available.
RefSeqiNP_990121.2, NM_204790.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000004011

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000059123; ENSGALP00000051075; ENSGALG00000002546
GeneIDi395568

Phylogenomic databases

GeneTreeiENSGT00940000159211
OrthoDBi199083at2759

Enzyme and pathway databases

ReactomeiR-GGA-1650814 Collagen biosynthesis and modifying enzymes

Family and domain databases

InterProiView protein in InterPro
IPR008160 Collagen
IPR013320 ConA-like_dom_sf
IPR000885 Fib_collagen_C
IPR001791 Laminin_G
PfamiView protein in Pfam
PF01410 COLFI, 1 hit
PF01391 Collagen, 5 hits
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002078 Fib_collagen_C, 1 hit
SMARTiView protein in SMART
SM00038 COLFI, 1 hit
SM00210 TSPN, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS51461 NC1_FIB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1D5PE74_CHICK
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1D5PE74
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2016
Last sequence update: April 10, 2019
Last modified: May 8, 2019
This is version 20 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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