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Protein

ATP synthase subunit alpha

Gene

atpA

Organism
Streptomyces sp. SolWspMP-sol7th
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.UniRule annotation

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei374Required for activityUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi173 – 180ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
Biological processATP synthesis, Hydrogen ion transportUniRule annotation, Ion transport, Transport
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit alphaUniRule annotation (EC:3.6.3.14UniRule annotation)
Alternative name(s):
ATP synthase F1 sector subunit alphaUniRule annotation
F-ATPase subunit alphaUniRule annotation
Gene namesi
Name:atpAUniRule annotation
ORF Names:GA0115246_1011715Imported
OrganismiStreptomyces sp. SolWspMP-sol7thImported
Taxonomic identifieri1839776 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000198581 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, CF(1)UniRule annotation, Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 96ATP-synt_ab_NInterPro annotationAdd BLAST67
Domaini153 – 376ATP-synt_abInterPro annotationAdd BLAST224
Domaini383 – 508ATP-synt_ab_CInterPro annotationAdd BLAST126

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.UniRule annotation

Family and domain databases

CDDicd01132 F1_ATPase_alpha, 1 hit
Gene3Di1.20.150.20, 1 hit
2.40.30.20, 1 hit
HAMAPiMF_01346 ATP_synth_alpha_bact, 1 hit
InterProiView protein in InterPro
IPR023366 ATP_synth_asu-like_sf
IPR000793 ATP_synth_asu_C
IPR038376 ATP_synth_asu_C_sf
IPR033732 ATP_synth_F1_a
IPR005294 ATP_synth_F1_asu
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR036121 ATPase_F1/V1/A1_a/bsu_N_sf
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF00306 ATP-synt_ab_C, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
SUPFAMiSSF50615 SSF50615, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00962 atpA, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1C4IQD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAELTIRPEE IRDALENFVQ SYKPDAASRE EVGTVTTAGD GIARIEGLPS
60 70 80 90 100
AMANELLKFE DGTLGLALNL EEREIGAIVL GEFSGVEEGQ PVTRTGEVLS
110 120 130 140 150
VGVGDGYLGR VVDPLGNPID GLGEIATSGR RALELQAPTV MQRKSVHEPM
160 170 180 190 200
ETGYKAVDAM TPIGRGQRQL IIGDRQTGKT ALAVDTIINQ RGNWESGDPK
210 220 230 240 250
KQVRCIYVAI GQKGSTIASV RGALEEAGAL EYTTIVASPA SDPAGFKYLA
260 270 280 290 300
PYTGSAIGQH WMYEGKHVLI IFDDLSKQAD AYRAVSLLLR RPPGREAYPG
310 320 330 340 350
DVFYLHSRLL ERCAKLSDDL GAGSMTGLPI VETKANDVSA FIPTNVISIT
360 370 380 390 400
DGQCFLESDL FNAGQRPALN VGISVSRVGG SAQHKAMKQV SGRLRLDLAQ
410 420 430 440 450
YRELESFAAF GSDLDAASKA QLGRGQRLVE LLKQDQYQPM ATEDQVVSVW
460 470 480 490 500
SATTGLMDEV PVADIRRFES ELLGWLHQTR QPLMTSIKEG GKMSDDTLTA
510 520 530
VGDAVKDFKK QFQTSDGQLL GDDASATAAK
Length:530
Mass (Da):57,033
Last modified:November 2, 2016 - v1
Checksum:i2022443A5D9DD84D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FMCN01000103 Genomic DNA Translation: SCD39161.1
RefSeqiWP_043254651.1, NZ_FMCN01000103.1

Similar proteinsi

Entry informationi

Entry nameiA0A1C4IQD3_9ACTN
AccessioniPrimary (citable) accession number: A0A1C4IQD3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2016
Last sequence update: November 2, 2016
Last modified: March 28, 2018
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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