Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Apical junction molecule

Gene

ajm-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Controls adherens junction integrity (PubMed:11715019). Required for the correct rate and completion of elongation of the embryos (PubMed:11715019).1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri1445 – 1488MYND-typePROSITE-ProRule annotationAdd BLAST44

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • cytoskeletal protein binding Source: WormBase
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

  • cell-cell junction organization Source: WormBase
  • embryo development ending in birth or egg hatching Source: WormBase

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Apical junction molecule
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ajm-1Imported
ORF Names:C25A11.4Imported, CELE_C25A11.4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
C25A11.4a ; CE27083 ; WBGene00000100 ; ajm-1
C25A11.4d ; CE51720 ; WBGene00000100 ; ajm-1
C25A11.4e ; CE51736 ; WBGene00000100 ; ajm-1
C25A11.4f ; CE51707 ; WBGene00000100 ; ajm-1
C25A11.4g ; CE51727 ; WBGene00000100 ; ajm-1
C25A11.4h ; CE30251 ; WBGene00000100 ; ajm-1
C25A11.4i ; CE51744 ; WBGene00000100 ; ajm-1
C25A11.4j ; CE51702 ; WBGene00000100 ; ajm-1
C25A11.4k ; CE51717 ; WBGene00000100 ; ajm-1
C25A11.4l ; CE51733 ; WBGene00000100 ; ajm-1
C25A11.4m ; CE51748 ; WBGene00000100 ; ajm-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell junction, Cell membrane, Cell projection, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mutant embryos enclose normally and initiate elongation without obvious morphological abnormalities, yet at a slower rate than the wild type. Elongation is consistently arrested at the 2-3-fold stage, accompanied by the formation of a large vacuole in the posterior region.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004429281 – 1644Apical junction moleculeAdd BLAST1644

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed by epithelial cells (PubMed:11715019). Expressed in sensory neuron dendritic tips (PubMed:27623382).2 Publications

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expression occurs in the embryonic hypodermis, pharynx and intestine, as well as in postembryonic epithelia, including the vulva, uterus, spermathecae, pharynx, intestine, hindgut, hypodermis and male tail.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00000100 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with dlj-1 (via L27 domain); the interaction regulates ajm-1 apical junction location.2 Publications

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
A0A1C3NSL9, 6 interactors

STRING: functional protein association networks

More...
STRINGi
6239.C25A11.4a

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A1C3NSL9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili428 – 924Sequence analysisAdd BLAST497

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The coiled-coil domain is sufficient to localize to apical junctions.1 Publication

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1445 – 1488MYND-typePROSITE-ProRule annotationAdd BLAST44

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEQ7 Eukaryota
ENOG4110VJZ LUCA

Identification of Orthologs from Complete Genome Data

More...
OMAi
YHHVETP

Database of Orthologous Groups

More...
OrthoDBi
EOG091G02B5

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038825 Apical_junction
IPR002893 Znf_MYND

The PANTHER Classification System

More...
PANTHERi
PTHR21517 PTHR21517, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50865 ZF_MYND_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (11+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 11 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 11 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: A0A1C3NSL9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSTTTPEKPE EIIDATGTSD TAEKIEVVIS KEEPAEQKNE VEEPDYAQVP
60 70 80 90 100
AESEDDAAQE LAPTDSAIQV VHVLEAPQKA ELVTIPLAHS EAEDHKLADA
110 120 130 140 150
DRDQEEELVF NEERRKTVTM DDNASLRSAS ITFDANRDEQ DLLNESFASN
160 170 180 190 200
PTDETVLMQK TKDEMDATSE RPRSPLDLPP PPASVVLHPS APPPPPPPLS
210 220 230 240 250
STEVVGNTTT TTTTHYAPKT WNDPSITTAP KIPVSLLSGA QPLPSVLTQR
260 270 280 290 300
TTTSSYSAPN YSASSMSGVP SDVAPPPPLP IPNQSSSSAA SYQHHHASSI
310 320 330 340 350
SKSISSSRED LLSEHATSRS TVREIPVHRA PSTAPSHSSV FEYHMMPTTT
360 370 380 390 400
STYHHVETPS DEYYRREVMT RTIITRSTEA LSQTPLGRPA SPLDRYLPYP
410 420 430 440 450
TTTTTTSGDG RTREEKTVDY KVTYHRDIEE QERRIREDQA RRQQEEQDRR
460 470 480 490 500
DREDNARRIL AQREHQEMER LREQQNLSER ALAERERADK ERLQQERLLR
510 520 530 540 550
QQREKKRREE WDRLESIRLA EEEAELARRR ALEKERIDRE KAEEERKTME
560 570 580 590 600
RLERERARLE RERLEEERRQ KEKAETERIE RERREHERIE IERIERIKRE
610 620 630 640 650
RIERERRERE EKKAEEDRLL RERLELERIE RERRELEARE RQELELQRRE
660 670 680 690 700
AEDRERQRLE DEAREMRRRE EERREAELVA DVHRQAEERE RLRKRQEREE
710 720 730 740 750
AERLERIRLE QQKIDMERID AERRERERKE EERREFELIE AARRKKEARD
760 770 780 790 800
RDRLDEMERE RVREEEERRE KERREQERRI AAEKERKRRQ EEEEEIARLN
810 820 830 840 850
ELQRAAAARQ AQRNAELDRQ RQRDELDRKA QELSEREMRE KERRDRERAN
860 870 880 890 900
EEAQLADLLE RERHNQLIRE NERREAVERA NNRRLEDRRS RDKLDHIVRE
910 920 930 940 950
RSEKEQFELE KRRLLAEKEA MNRKKNHLLS SETLAKLTQP MYYTTREPEV
960 970 980 990 1000
TTKVERQVIE RIDRNVWVED VPYAPSQSAM GYLDNDENNR DRLYNPNDLN
1010 1020 1030 1040 1050
RNGSSRSRYQ RAKNEKARRD FYHSSQDSAD PVTERFRKST DDLTTRSRPE
1060 1070 1080 1090 1100
YRGPLLQKFH DSEFRTTALN ETDGLPYRRM GPSPYEQPFA KLLEETERRY
1110 1120 1130 1140 1150
AHYNSRASNP SIYQSSRYYY PERHGQPQHT DNTRAESVVA YERESRRESP
1160 1170 1180 1190 1200
ADQAHIRSRS ADYLMDRRIR EETEVPENQL QKTRVEPHDQ SPRESRISEY
1210 1220 1230 1240 1250
EMRFRKSTEK LTVPDWYREN RPQGQTAQTS TYRYGNGVEP MSTTTTTTTV
1260 1270 1280 1290 1300
INGTSSHQQA PPPVPPQPIG NIGLPRGMFD RYKDDIEELR RSRSSLHQTG
1310 1320 1330 1340 1350
QQETSNRQGS TLSVGGIVDQ GHALPGYTVS EVPNAWNLHT SRTSRVVEVA
1360 1370 1380 1390 1400
DTFVGTSSHE YGNFTNRYGG RVTIEEVLDS IFQKVTPTNQ RLNFDRSYPQ
1410 1420 1430 1440 1450
ADELFQGNVD GPGIYTNNYS VMRQVLKSPE RAEHILQNEE LFVRCTECHR
1460 1470 1480 1490 1500
TRELSAARLF FVSCKHCYTY YCSRECRHNN WPNHSGRCSF ARINTLCKDV
1510 1520 1530 1540 1550
IMKVREDEQA QAFMSKVARD GFSVSGRGSV NIRLSSPQLA QAYVSNGWRA
1560 1570 1580 1590 1600
LSAYPNDQLL YYYTVKALIA ERKEPSLIAL CNRYEPREKF ILSVSIIADI
1610 1620 1630 1640
EHCPETPPPE TRELSAVQFS SPRSRYEAIQ NQNAPYFSEF AHNV
Length:1,644
Mass (Da):193,402
Last modified:November 2, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF57A629DDA31B700
GO
Isoform 2 (identifier: A0A1C3NSL9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-467: Missing.

Show »
Length:1,177
Mass (Da):141,635
Checksum:i5DFF1E5160AD474D
GO
Isoform 3 (identifier: A0A1C3NSL9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-368: Missing.

Show »
Length:1,276
Mass (Da):153,476
Checksum:iC4CD7D36E2A46CDD
GO
Isoform 4 (identifier: A0A1C3NSL9-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-119: Missing.

Show »
Length:1,525
Mass (Da):180,283
Checksum:i2229FC11CF2D4531
GO
Isoform 5 (identifier: A0A1C3NSL9-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-96: MSTTTPEKPE...LAHSEAEDHK → MIPFDPTTSEIHTQKMSQFIV

Show »
Length:1,569
Mass (Da):185,462
Checksum:iAAF18F406D1B7769
GO
Isoform 6 (identifier: A0A1C3NSL9-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MDIENLQSSN...GKSNTSTSQM

Show »
Length:1,905
Mass (Da):222,054
Checksum:i3DEE54944F37ACD1
GO
Isoform 7 (identifier: A0A1C3NSL9-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-265: Missing.

Show »
Length:1,379
Mass (Da):164,769
Checksum:i35CD4AEF8C74813D
GO
Isoform 8 (identifier: A0A1C3NSL9-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MDIENLQSSN...GKSNTSTSQM
     1088-1128: Missing.

Show »
Length:1,864
Mass (Da):217,081
Checksum:i8CC51B98B43FB6E0
GO
Isoform 9 (identifier: A0A1C3NSL9-9) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-157: Missing.

Show »
Length:1,487
Mass (Da):176,098
Checksum:i26C4CFA0FA10CCF1
GO
Isoform 10 (identifier: A0A1C3NSL9-10) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-164: Missing.

Show »
Length:1,480
Mass (Da):175,237
Checksum:iEC9FAA97040EC7BA
GO
Isoform 11 (identifier: A0A1C3NSL9-11) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-344: Missing.

Show »
Length:1,300
Mass (Da):156,389
Checksum:i753E213AD7B8D061
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q95ZY7Q95ZY7_CAEEL
Apical junction molecule
ajm-1 C25A11.4, CELE_C25A11.4
1,573Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H2KYC5H2KYC5_CAEEL
Apical junction molecule
ajm-1 C25A11.4, CELE_C25A11.4
1,293Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0592851 – 467Missing in isoform 2. Add BLAST467
Alternative sequenceiVSP_0592861 – 368Missing in isoform 3. Add BLAST368
Alternative sequenceiVSP_0592871 – 344Missing in isoform 11. Add BLAST344
Alternative sequenceiVSP_0592881 – 265Missing in isoform 7. Add BLAST265
Alternative sequenceiVSP_0592891 – 164Missing in isoform 10. Add BLAST164
Alternative sequenceiVSP_0592901 – 157Missing in isoform 9. Add BLAST157
Alternative sequenceiVSP_0592911 – 119Missing in isoform 4. Add BLAST119
Alternative sequenceiVSP_0592921 – 96MSTTT…AEDHK → MIPFDPTTSEIHTQKMSQFI V in isoform 5. Add BLAST96
Alternative sequenceiVSP_0592931M → MDIENLQSSNNRSQKSRPPD GFNAILQTAFSAILAFVLSL RIIVFATARKRLTTTAANPD IQVEEASSSSSDTSSDTEIV EEGVFIQRQGEPTMSEKKPA QGMPSVMSLLQTDEILSSCS DDEPTTSGLIPLPSLIQSNM SVLPNFLHTINEEESDEIRS LTGSSLASPRTVVDRRLSNI SLLSPTPDEDFGLEQQEQQP ENSEEVRGRESRTSLEEERI VVGEPRTTRQIEITQSASED DRLDLLKELAKIGKSNTSTS QM in isoform 6 and isoform 8. 1
Alternative sequenceiVSP_0592941088 – 1128Missing in isoform 8. Add BLAST41

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284606 Genomic DNA Translation: SBV53382.1
BX284606 Genomic DNA Translation: CCD62273.2
BX284606 Genomic DNA Translation: SBV53392.1
BX284606 Genomic DNA Translation: SBV53384.1
BX284606 Genomic DNA Translation: SBV53383.1
BX284606 Genomic DNA Translation: SBV53380.1
BX284606 Genomic DNA Translation: SBV53390.1
BX284606 Genomic DNA Translation: CCD62272.2
BX284606 Genomic DNA Translation: SBV53381.1
BX284606 Genomic DNA Translation: CCD62269.1
BX284606 Genomic DNA Translation: SBV53391.1

NCBI Reference Sequences

More...
RefSeqi
NP_001317735.1, NM_001330905.1 [A0A1C3NSL9-8]
NP_001317736.1, NM_001330915.1 [A0A1C3NSL9-2]
NP_001317887.1, NM_001330904.1 [A0A1C3NSL9-6]
NP_001317888.1, NM_001330911.1 [A0A1C3NSL9-9]
NP_001317889.1, NM_001330908.1 [A0A1C3NSL9-1]
NP_001317890.1, NM_001330909.1 [A0A1C3NSL9-5]
NP_001317891.1, NM_001330910.1 [A0A1C3NSL9-4]
NP_001317897.1, NM_001330912.1 [A0A1C3NSL9-7]
NP_001317898.1, NM_001330913.1 [A0A1C3NSL9-11]
NP_001317899.1, NM_001330914.1 [A0A1C3NSL9-3]
NP_509536.1, NM_077135.1 [A0A1C3NSL9-10]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Cel.5835

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C25A11.4a; C25A11.4a; WBGene00000100 [A0A1C3NSL9-10]
C25A11.4d; C25A11.4d; WBGene00000100 [A0A1C3NSL9-8]
C25A11.4e; C25A11.4e; WBGene00000100 [A0A1C3NSL9-2]
C25A11.4f.1; C25A11.4f.1; WBGene00000100 [A0A1C3NSL9-6]
C25A11.4f.2; C25A11.4f.2; WBGene00000100 [A0A1C3NSL9-6]
C25A11.4g; C25A11.4g; WBGene00000100 [A0A1C3NSL9-9]
C25A11.4h; C25A11.4h; WBGene00000100 [A0A1C3NSL9-7]
C25A11.4i; C25A11.4i; WBGene00000100 [A0A1C3NSL9-11]
C25A11.4j; C25A11.4j; WBGene00000100 [A0A1C3NSL9-3]
C25A11.4k; C25A11.4k; WBGene00000100 [A0A1C3NSL9-1]
C25A11.4l; C25A11.4l; WBGene00000100 [A0A1C3NSL9-5]
C25A11.4m; C25A11.4m; WBGene00000100 [A0A1C3NSL9-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181148

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_C25A11.4

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: SBV53382.1
BX284606 Genomic DNA Translation: CCD62273.2
BX284606 Genomic DNA Translation: SBV53392.1
BX284606 Genomic DNA Translation: SBV53384.1
BX284606 Genomic DNA Translation: SBV53383.1
BX284606 Genomic DNA Translation: SBV53380.1
BX284606 Genomic DNA Translation: SBV53390.1
BX284606 Genomic DNA Translation: CCD62272.2
BX284606 Genomic DNA Translation: SBV53381.1
BX284606 Genomic DNA Translation: CCD62269.1
BX284606 Genomic DNA Translation: SBV53391.1
RefSeqiNP_001317735.1, NM_001330905.1 [A0A1C3NSL9-8]
NP_001317736.1, NM_001330915.1 [A0A1C3NSL9-2]
NP_001317887.1, NM_001330904.1 [A0A1C3NSL9-6]
NP_001317888.1, NM_001330911.1 [A0A1C3NSL9-9]
NP_001317889.1, NM_001330908.1 [A0A1C3NSL9-1]
NP_001317890.1, NM_001330909.1 [A0A1C3NSL9-5]
NP_001317891.1, NM_001330910.1 [A0A1C3NSL9-4]
NP_001317897.1, NM_001330912.1 [A0A1C3NSL9-7]
NP_001317898.1, NM_001330913.1 [A0A1C3NSL9-11]
NP_001317899.1, NM_001330914.1 [A0A1C3NSL9-3]
NP_509536.1, NM_077135.1 [A0A1C3NSL9-10]
UniGeneiCel.5835

3D structure databases

SMRiA0A1C3NSL9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA0A1C3NSL9, 6 interactors
STRINGi6239.C25A11.4a

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC25A11.4a; C25A11.4a; WBGene00000100 [A0A1C3NSL9-10]
C25A11.4d; C25A11.4d; WBGene00000100 [A0A1C3NSL9-8]
C25A11.4e; C25A11.4e; WBGene00000100 [A0A1C3NSL9-2]
C25A11.4f.1; C25A11.4f.1; WBGene00000100 [A0A1C3NSL9-6]
C25A11.4f.2; C25A11.4f.2; WBGene00000100 [A0A1C3NSL9-6]
C25A11.4g; C25A11.4g; WBGene00000100 [A0A1C3NSL9-9]
C25A11.4h; C25A11.4h; WBGene00000100 [A0A1C3NSL9-7]
C25A11.4i; C25A11.4i; WBGene00000100 [A0A1C3NSL9-11]
C25A11.4j; C25A11.4j; WBGene00000100 [A0A1C3NSL9-3]
C25A11.4k; C25A11.4k; WBGene00000100 [A0A1C3NSL9-1]
C25A11.4l; C25A11.4l; WBGene00000100 [A0A1C3NSL9-5]
C25A11.4m; C25A11.4m; WBGene00000100 [A0A1C3NSL9-4]
GeneIDi181148
KEGGicel:CELE_C25A11.4

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181148
WormBaseiC25A11.4a ; CE27083 ; WBGene00000100 ; ajm-1
C25A11.4d ; CE51720 ; WBGene00000100 ; ajm-1
C25A11.4e ; CE51736 ; WBGene00000100 ; ajm-1
C25A11.4f ; CE51707 ; WBGene00000100 ; ajm-1
C25A11.4g ; CE51727 ; WBGene00000100 ; ajm-1
C25A11.4h ; CE30251 ; WBGene00000100 ; ajm-1
C25A11.4i ; CE51744 ; WBGene00000100 ; ajm-1
C25A11.4j ; CE51702 ; WBGene00000100 ; ajm-1
C25A11.4k ; CE51717 ; WBGene00000100 ; ajm-1
C25A11.4l ; CE51733 ; WBGene00000100 ; ajm-1
C25A11.4m ; CE51748 ; WBGene00000100 ; ajm-1

Phylogenomic databases

eggNOGiENOG410IEQ7 Eukaryota
ENOG4110VJZ LUCA
OMAiYHHVETP
OrthoDBiEOG091G02B5

Miscellaneous databases

Protein Ontology

More...
PROi
PR:A0A1C3NSL9

Gene expression databases

BgeeiWBGene00000100 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

Family and domain databases

InterProiView protein in InterPro
IPR038825 Apical_junction
IPR002893 Znf_MYND
PANTHERiPTHR21517 PTHR21517, 1 hit
PROSITEiView protein in PROSITE
PS50865 ZF_MYND_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAJM1_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1C3NSL9
Secondary accession number(s): A0A1C3NSK1
, A0A1C3NSK9, A0A1C3NSL1, A0A1C3NSL6, A0A1C3NSM8, A0A1C3NSP2, A0A1C3NSQ2, G4RTG4, H2KYC4, H2KYC6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 31, 2018
Last sequence update: November 2, 2016
Last modified: December 5, 2018
This is version 21 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again