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Entry version 12 (11 Dec 2019)
Sequence version 1 (02 Nov 2016)
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Protein

Integrase catalytic domain-containing protein

Gene

g.49609

Organism
Graphocephala atropunctata
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Integrase catalytic domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:g.49609Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGraphocephala atropunctataImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri36148 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraHemipteraAuchenorrhynchaMembracoideaCicadellidaeCicadellinaeCicadelliniGraphocephala

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1285 – 1478Integrase catalyticInterPro annotationAdd BLAST194

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni147 – 190DisorderedSequence analysisAdd BLAST44

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.420.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005312 DUF1759
IPR040676 DUF5641
IPR001584 Integrase_cat-core
IPR041588 Integrase_H2C2
IPR008737 Peptidase_asp_put
IPR008042 Retrotrans_Pao
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05585 DUF1758, 1 hit
PF03564 DUF1759, 1 hit
PF18701 DUF5641, 1 hit
PF17921 Integrase_H2C2, 1 hit
PF05380 Peptidase_A17, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098 SSF53098, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50994 INTEGRASE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

A0A1B6LLT3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
IQKFSFLKSY LEYPALSVID SFDFKEDNYQ AAYDKLVERY TDKRLVGTHY
60 70 80 90 100
LNKLMQFKPL TNGSPHQLRQ FIDVFCVQYE SLKALNIPDL ADFVVFNLAL
110 120 130 140 150
KVLDPDTKRL FEDKHSKKEF PTFMDLSLFV TEQHKVASIV QAPSVSKLST
160 170 180 190 200
NPSYASSNVK SSKSSKQSLF TKSNVSNTQV PKGNLPQGKR TETYNVNVKC
210 220 230 240 250
SLCQREHRIS SCDKFVALNP QERLETATNL KLCYACLGSH LRSNCKSKFS
260 270 280 290 300
CRTCKSKSHH SLLHCDQPQM PQSSNEPNNS LLVSNQCTSS TEATTNALSC
310 320 330 340 350
HVKSPVSSHN SPTIGLLGTV QCRVLSSSGD WEKCRAVIDP ASESSFITES
360 370 380 390 400
LVQTLRLPRK KYSVDVVGVG SSSFSNNRGC VTCSIVPLHN EDPMLSVEAI
410 420 430 440 450
VLKTISSHMP KVKLDSSLRN RFSNCQLADP EFDKPGPIDL LLGVQHFSDI
460 470 480 490 500
LSDNCAHIKG SPAALDTVFG FIIFGKVPSL HKSPISTTMF THTPPLEDML
510 520 530 540 550
RRFWESEEPS HVILKTDNET QCEKFFLETT TRDSHGRYQV SLPFKDTTPP
560 570 580 590 600
ENLGSTRHVA HKRLLSLEKR LSKTPDFKQQ YNANLEDYVT QGHMRPTSTN
610 620 630 640 650
VDYLLTHHGV VKESTTTHVR VVFNASEKSN IGKSLNDFLL SGPKLQSDIS
660 670 680 690 700
QILLSFRMNP VALTCDIKQM YRCILLNPQD VQYTHILWRN DVNIPITEWE
710 720 730 740 750
LTTLPFGLTC SPYLAQQTIK QLVVDEGENF PNASKVLTSN IYVDDIVCAV
760 770 780 790 800
PSENEAIELY NELTDLLGKG GFSLRKYSSN NVGVLSQIPD DHQESPVSFE
810 820 830 840 850
SSNCVKLLGF LWDPTSDEFG YKFSCENPVT TKRGVLSQVA RIYDINGYLT
860 870 880 890 900
PVTLWIKYFI QRLWLAGLDW DESLPQSLAQ LWLQFTSQLH EIEKIRIPRY
910 920 930 940 950
ISFNDPKKIT IIGFCDASEK GYGACVYIRV QSAENHIQVN LLKSKSKVAP
960 970 980 990 1000
LKPVTIPRLE LNGALLLSRV MGSLKDFLST QSISEVICFT DSTTVLSWLH
1010 1020 1030 1040 1050
TPPHQLKTYV SNRVVEIVQV LPPSVWKHIP GTNNPADLAS RGLFPSQLVK
1060 1070 1080 1090 1100
NEHWWYGPKF LQTPYSQWPQ SSITVIDPIP ERKPESLSLI SQDKGNDSVI
1110 1120 1130 1140 1150
ESLLQSYSSF TKVQRVLAYV LRFVSNVRSK VNERRFGELI HSELNNALKK
1160 1170 1180 1190 1200
CIQFTQEKYY SQEIICIKNS KPIKGFVKHL TPFLCNEGYL MVGGRLAQAP
1210 1220 1230 1240 1250
ISSHRKHPYL IPRKSRLAEL ICAHYHMLTL HGGPQLMQSL IQRKFWIPGI
1260 1270 1280 1290 1300
RYLLRSVVFK CMNCYRFKAK PLEPLMSDVP RFRFKTIRPF VNTGVDLTGP
1310 1320 1330 1340 1350
FLCKESTRRN AKTYKCWIVM FICLSTRAVY IDLVSELSTA AFLSSLDRFI
1360 1370 1380 1390 1400
SRRGVPSTMY SDQGTNFVGA ARELKDIYEV LKQGNDHIKS YCEERKISWQ
1410 1420 1430 1440 1450
FNPPSAPNFG GSWESAIKSM KHHLKRVIAD RPLSYEEYLT LLAKIEAILN
1460 1470 1480 1490 1500
SRPLCPVSSS PSDGFDYLTP GHFLVGAPVL LSRPDQDLSN QPINFRLRWQ
1510 1520 1530 1540 1550
LLSRSIQKVW QRWSQEYFHT LMQRPKWESS TPNLTPGKMI LLSEKNLPPT
1560 1570 1580 1590
LWAIGRVIEV YPGNDGVVRV AKIKTAKGTF TRPVNKLCLL PFQD
Length:1,594
Mass (Da):180,637
Last modified:November 2, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i32C2C914205B25A7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GEBQ01015458 Transcribed RNA Translation: JAT24519.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GEBQ01015458 Transcribed RNA Translation: JAT24519.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR005312 DUF1759
IPR040676 DUF5641
IPR001584 Integrase_cat-core
IPR041588 Integrase_H2C2
IPR008737 Peptidase_asp_put
IPR008042 Retrotrans_Pao
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PfamiView protein in Pfam
PF05585 DUF1758, 1 hit
PF03564 DUF1759, 1 hit
PF18701 DUF5641, 1 hit
PF17921 Integrase_H2C2, 1 hit
PF05380 Peptidase_A17, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50994 INTEGRASE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1B6LLT3_9HEMI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1B6LLT3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2016
Last sequence update: November 2, 2016
Last modified: December 11, 2019
This is version 12 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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