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Entry version 44 (29 Sep 2021)
Sequence version 1 (02 Nov 2016)
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Protein

30S ribosomal protein S4

Gene

rpsD

Organism
Enterococcus faecalis (Streptococcus faecalis)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.

UniRule annotation

With S5 and S12 plays an important role in translational accuracy.

UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal proteinUniRule annotationARBA annotation, RNA-binding, rRNA-bindingUniRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
30S ribosomal protein S4UniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rpsDUniRule annotationImported
ORF Names:BZG32_14835Imported, CUM81_11970Imported, DAI13_15225Imported, EGW70_06610Imported, EU507_06310Imported, EY666_04855Imported, GTI81_10825Imported, H7D67_08060Imported, H9Q64_14110Imported, KUB3007_C24820Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEnterococcus faecalis (Streptococcus faecalis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1351 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000239475 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000275941 Componenti: Unassembled WGS sequence
  • UP000268003 Componenti: Chromosome
  • UP000550093 Componenti: Unassembled WGS sequence
  • UP000244140 Componenti: Unassembled WGS sequence
  • UP000516122 Componenti: Chromosome
  • UP000429730 Componenti: Unassembled WGS sequence
  • UP000292223 Componenti: Unassembled WGS sequence
  • UP000187983 Componenti: Chromosome
  • UP000305511 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.

UniRule annotation

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
A0A1B4XRV7, 1 interactor

STRING: functional protein association networks

More...
STRINGi
1201292.DR75_1794

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 92Ribosomal_S4InterPro annotationAdd BLAST90
Domaini93 – 157S4InterPro annotationAdd BLAST65

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni22 – 45DisorderedSequence analysisAdd BLAST24

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uS4 family.UniRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0522, Bacteria

Database of Orthologous Groups

More...
OrthoDBi
1211060at2

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00165, S4, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.10.290.10, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_01306_B, Ribosomal_S4_B, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022801, Ribosomal_S4/S9
IPR001912, Ribosomal_S4/S9_N
IPR005709, Ribosomal_S4_bac-type
IPR018079, Ribosomal_S4_CS
IPR002942, S4_RNA-bd
IPR036986, S4_RNA-bd_sf

The PANTHER Classification System

More...
PANTHERi
PTHR11831, PTHR11831, 1 hit
PTHR11831:SF4, PTHR11831:SF4, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00163, Ribosomal_S4, 1 hit
PF01479, S4, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01390, Ribosomal_S4, 1 hit
SM00363, S4, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01017, rpsD_bact, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00632, RIBOSOMAL_S4, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1B4XRV7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRYTGPSWK VSRRLGISLS GTGKELARRP YKPGQHGPNS RGKVSEYGMQ
60 70 80 90 100
LTEKQKLRHM YGMNERQFRT LFIKASKIKE GKHGVNFMVL LEQRLDNVVY
110 120 130 140 150
RLGLATTRRQ ARQLVNHGHI TVDGKRVDIP SYHVEVGQVI GVREKSQNIS
160 170 180 190 200
TIKEAVEATV GRPAFVSFDT EKLEGSFTRL PERDELYPEI DEALVVEYYN

QKL
Length:203
Mass (Da):23,234
Last modified:November 2, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE372215A9EE50093
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP019512 Genomic DNA Translation: AQL54903.1
AP018543 Genomic DNA Translation: BBD29098.1
JACKWH010000001 Genomic DNA Translation: MBB6708766.1
WVTJ01000020 Genomic DNA Translation: MXS53206.1
PTWC01000089 Genomic DNA Translation: PQB43891.1
PZZH01000001 Genomic DNA Translation: PTN79042.1
CP060804 Genomic DNA Translation: QNP37576.1
RKOR01000014 Genomic DNA Translation: ROY50695.1
SEWT01000003 Genomic DNA Translation: RYU33752.1
SIYF01000103 Genomic DNA Translation: TKK89173.1

NCBI Reference Sequences

More...
RefSeqi
WP_002365342.1, NZ_WYAE01000011.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AQL54903; AQL54903; BZG32_14835
BBD29098; BBD29098; KUB3007_C24820
OGX75623; OGX75623; BHU49_06540
OSH07929; OSH07929; ELS84_2258
PQC71007; PQC71007; CUN08_07245
PTN79042; PTN79042; DAI13_15225
VTT48770; VTT48770; NCTC8732_02632

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
64009676

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ene:ENT_28170

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1351.219.peg.2598

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP019512 Genomic DNA Translation: AQL54903.1
AP018543 Genomic DNA Translation: BBD29098.1
JACKWH010000001 Genomic DNA Translation: MBB6708766.1
WVTJ01000020 Genomic DNA Translation: MXS53206.1
PTWC01000089 Genomic DNA Translation: PQB43891.1
PZZH01000001 Genomic DNA Translation: PTN79042.1
CP060804 Genomic DNA Translation: QNP37576.1
RKOR01000014 Genomic DNA Translation: ROY50695.1
SEWT01000003 Genomic DNA Translation: RYU33752.1
SIYF01000103 Genomic DNA Translation: TKK89173.1
RefSeqiWP_002365342.1, NZ_WYAE01000011.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6O8Welectron microscopy3.53d2-202[»]
6O8Xelectron microscopy3.68d2-202[»]
6O8Yelectron microscopy4.14d2-202[»]
6O8Zelectron microscopy3.49d2-202[»]
6O90electron microscopy3.49d2-202[»]
6W6Pelectron microscopy2.90d2-202[»]
6WUBelectron microscopy3.20d2-202[»]
7NHKelectron microscopy2.90e1-203[»]
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...
PDBe-KBiSearch...

Protein-protein interaction databases

IntActiA0A1B4XRV7, 1 interactor
STRINGi1201292.DR75_1794

Genome annotation databases

EnsemblBacteriaiAQL54903; AQL54903; BZG32_14835
BBD29098; BBD29098; KUB3007_C24820
OGX75623; OGX75623; BHU49_06540
OSH07929; OSH07929; ELS84_2258
PQC71007; PQC71007; CUN08_07245
PTN79042; PTN79042; DAI13_15225
VTT48770; VTT48770; NCTC8732_02632
GeneIDi64009676
KEGGiene:ENT_28170
PATRICifig|1351.219.peg.2598

Phylogenomic databases

eggNOGiCOG0522, Bacteria
OrthoDBi1211060at2

Family and domain databases

CDDicd00165, S4, 1 hit
Gene3Di3.10.290.10, 1 hit
HAMAPiMF_01306_B, Ribosomal_S4_B, 1 hit
InterProiView protein in InterPro
IPR022801, Ribosomal_S4/S9
IPR001912, Ribosomal_S4/S9_N
IPR005709, Ribosomal_S4_bac-type
IPR018079, Ribosomal_S4_CS
IPR002942, S4_RNA-bd
IPR036986, S4_RNA-bd_sf
PANTHERiPTHR11831, PTHR11831, 1 hit
PTHR11831:SF4, PTHR11831:SF4, 1 hit
PfamiView protein in Pfam
PF00163, Ribosomal_S4, 1 hit
PF01479, S4, 1 hit
SMARTiView protein in SMART
SM01390, Ribosomal_S4, 1 hit
SM00363, S4, 1 hit
TIGRFAMsiTIGR01017, rpsD_bact, 1 hit
PROSITEiView protein in PROSITE
PS00632, RIBOSOMAL_S4, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1B4XRV7_ENTFL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1B4XRV7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2016
Last sequence update: November 2, 2016
Last modified: September 29, 2021
This is version 44 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources
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