UniProtKB - A0A1B0GUR8 (A0A1B0GUR8_HUMAN)
Protein
Submitted name:
Protein CLN8
Gene
CLN8
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Protein CLN8Imported |
Gene namesi | Name:CLN8Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:2079, CLN8 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-UniRule
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 21 – 42 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 62 – 84 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 104 – 121 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 133 – 153 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 62 – 216 | TLCInterPro annotationAdd BLAST | 155 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT01010000222424 |
Family and domain databases
InterProi | View protein in InterPro IPR006634, TLC-dom |
Pfami | View protein in Pfam PF03798, TRAM_LAG1_CLN8, 1 hit |
SMARTi | View protein in SMART SM00724, TLC, 1 hit |
PROSITEi | View protein in PROSITE PS50922, TLC, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
A0A1B0GUR8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNPASDGGTS ESIFDLDYAS WGIRSTLMVA GFVFYLGVFV VCHQLSSSLN
60 70 80 90 100
ATYRSLVARE KVFWDLAATR AVFGVQSTAA GLWALLGDPV LHADKARGQQ
110 120 130 140 150
NWCWFHITTA TGFFCFENVA VHLSNLIFRT FDLFLVIHHL FAFLGFLGCL
160 170 180 190 200
VNLQAGHYLA MTTLLLEMST PFTCVSWMLL KESWVIGTQG AENALASDSR
210
SVQIQSFSHP QELPPE
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9UBY8 | CLN8_HUMAN | Protein CLN8 | CLN8 C8orf61 | 286 | Annotation score: | ||
A0A0J9YWD2 | A0A0J9YWD2_HUMAN | Protein CLN8 | CLN8 | 216 | Annotation score: | ||
A0A0J9YYK8 | A0A0J9YYK8_HUMAN | Protein CLN8 | CLN8 | 135 | Annotation score: | ||
A0A0J9YX19 | A0A0J9YX19_HUMAN | Protein CLN8 | CLN8 | 171 | Annotation score: | ||
A0A1B0GU79 | A0A1B0GU79_HUMAN | Protein CLN8 | CLN8 | 77 | Annotation score: | ||
A0A0J9YXY6 | A0A0J9YXY6_HUMAN | Protein CLN8 | CLN8 | 80 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC100810 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000636934; ENSP00000490218; ENSG00000182372 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC100810 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | A0A1B0GUR8 |
Protocols and materials databases
Antibodypediai | 21957, 136 antibodies |
Genome annotation databases
Ensembli | ENST00000636934; ENSP00000490218; ENSG00000182372 |
Organism-specific databases
HGNCi | HGNC:2079, CLN8 |
OpenTargetsi | ENSG00000182372 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT01010000222424 |
Miscellaneous databases
ChiTaRSi | CLN8, human |
Gene expression databases
ExpressionAtlasi | A0A1B0GUR8, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR006634, TLC-dom |
Pfami | View protein in Pfam PF03798, TRAM_LAG1_CLN8, 1 hit |
SMARTi | View protein in SMART SM00724, TLC, 1 hit |
PROSITEi | View protein in PROSITE PS50922, TLC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A1B0GUR8_HUMAN | |
Accessioni | A0A1B0GUR8Primary (citable) accession number: A0A1B0GUR8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 5, 2016 |
Last sequence update: | October 5, 2016 | |
Last modified: | December 2, 2020 | |
This is version 21 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |