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Entry version 19 (16 Jan 2019)
Sequence version 1 (05 Oct 2016)
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Protein
Submitted name:

Obscurin

Gene

OBSCN

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ObscurinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:OBSCNImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:15719 OBSCN

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000154358

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A0A1B0GTS2

PeptideAtlas

More...
PeptideAtlasi
A0A1B0GTS2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A1B0GTS2 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 83Ig-likeInterPro annotationAdd BLAST83
Domaini216 – 283SH3InterPro annotationAdd BLAST68
Domaini309 – 494DHInterPro annotationAdd BLAST186
Domaini512 – 621PHInterPro annotationAdd BLAST110
Domaini631 – 714Ig-likeInterPro annotationAdd BLAST84
Domaini725 – 817Ig-likeInterPro annotationAdd BLAST93
Domaini974 – 1062Ig-likeInterPro annotationAdd BLAST89
Domaini1085 – 1338Protein kinaseInterPro annotationAdd BLAST254
Domaini2080 – 2169Ig-likeInterPro annotationAdd BLAST90
Domaini2174 – 2266Fibronectin type-IIIInterPro annotationAdd BLAST93
Domaini2289 – 2541Protein kinaseInterPro annotationAdd BLAST253

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili453 – 480Sequence analysisAdd BLAST28
Coiled coili1835 – 1860Sequence analysisAdd BLAST26

Keywords - Domaini

Coiled coilSequence analysis, Immunoglobulin domainSAAS annotation, RepeatSAAS annotation, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154756

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00160 RhoGEF, 1 hit
cd12025 SH3_Obscurin_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.900.10, 1 hit
2.30.29.30, 1 hit
2.60.40.10, 6 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR011009 Kinase-like_dom_sf
IPR035526 Obscurin_SH3
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR015726 Ser/Thr_kin_striated-sp
IPR008271 Ser/Thr_kinase_AS
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR008266 Tyr_kinase_AS

The PANTHER Classification System

More...
PANTHERi
PTHR45065 PTHR45065, 6 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07679 I-set, 5 hits
PF00069 Pkinase, 2 hits
PF00621 RhoGEF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00409 IG, 5 hits
SM00408 IGc2, 5 hits
SM00233 PH, 1 hit
SM00325 RhoGEF, 1 hit
SM00220 S_TKc, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48065 SSF48065, 1 hit
SSF48726 SSF48726, 5 hits
SSF49265 SSF49265, 1 hit
SSF50044 SSF50044, 1 hit
SSF56112 SSF56112, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50010 DH_2, 1 hit
PS50853 FN3, 1 hit
PS50835 IG_LIKE, 5 hits
PS50003 PH_DOMAIN, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 2 hits
PS00108 PROTEIN_KINASE_ST, 1 hit
PS00109 PROTEIN_KINASE_TYR, 1 hit
PS50002 SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

A0A1B0GTS2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XSSITFSVKV EGRPVPTVHW LREEAERGVL WIGPDTPGYT VASSAQQHSL
60 70 80 90 100
VLLDVGRQHQ GTYTCIASNA AGQALCSASL HVSGLPKVEE QEKVKEALIS
110 120 130 140 150
TFLQGTTQAI SAQGLETASF ADLGGQRKEE PLAAKEALGH LSLAEVGTEE
160 170 180 190 200
FLQKLTSQIT EMVSAKITQA KLQVPGGDSD EDSKTPSASP RHGRSRPSSS
210 220 230 240 250
IQESSSESED GDARGEIFDI YVVTADYLPL GAEQDAITLR EGQYVEVLDA
260 270 280 290 300
AHPLRWLVRT KPTKSSPSRQ GWVSPAYLDR RLKLSPEWGA AEAPEFPGEA
310 320 330 340 350
VSEDEYKARL SSVIQELLSS EQAFVEELQF LQSHHLQHLE RCPHVPIAVA
360 370 380 390 400
GQKAVIFRNV RDIGRFHSSS FLQELQQCDT DDDVAMCFIK NQAAFEQYLE
410 420 430 440 450
FLVGRVQAES VVVSTAIQEF YKKYAEEALL AGDPSQPPPP PLQHYLEQPV
460 470 480 490 500
ERVQRYQALL KELIRNKARN RQNCALLEQA YAVVSALPQR AENKLHVSLM
510 520 530 540 550
ENYPGTLQAL GEPIRQGHFI VWEGAPGARM PWKGHNRHVF LFRNHLVICK
560 570 580 590 600
PRRDSRTDTV SYVFRNMMKL SSIDLNDQVE GDDRAFEVWQ EREDSVRKYL
610 620 630 640 650
LQARTAIIKS SWVKEICGIQ QRLALPVWRP PDFEEELADC TAELGETVKL
660 670 680 690 700
ACRVTGTPKP VISWYKDGKA VQVDPHHILI EDPDGSCALI LDSLTGVDSG
710 720 730 740 750
QYMCFAASAA GNCSTLGKIL VQVPPRFVNK VRASPFVEGE DAQFTCTIEG
760 770 780 790 800
APYPQIRWYK DGALLTTGNK FQTLSEPRSG LLVLVIRAAS KEDLGLYECE
810 820 830 840 850
LVNRLGSARA SAELRIQSPM LQAQEQCHRE QLVAAVEDTT LERADQEVTS
860 870 880 890 900
VLKRLLGPKA PGPSTGDLTG PGPCPRGAPA LQETGSQPPV TGTSEAPAVP
910 920 930 940 950
PRVPQPLLHE GPEQEPEAIA RAQEWTVPIR MEGAAWPGAG TGELLWDVHS
960 970 980 990 1000
HVVRETTQRT YTYQAIDTHT ARPPSMQVTI EDVQAQTGGT AQFEAIIEGD
1010 1020 1030 1040 1050
PQPSVTWYKD SVQLVDSTRL SQQQEGTTYS LVLRHVASKD AGVYTCLAQN
1060 1070 1080 1090 1100
TGGQVLCKAE LLVLGGDNEP DSEKQSHRRK LHSFYEVKEE IGRGVFGFVK
1110 1120 1130 1140 1150
RVQHKGNKIL CAAKFIPLRS RTRAQAYRER DILAALSHPL VTGLLDQFET
1160 1170 1180 1190 1200
RKTLILILEL CSSEELLDRL YRKGVVTEAE VKVYIQQLVE GLHYLHSHGV
1210 1220 1230 1240 1250
LHLDIKPSNI LMVHPAREDI KICDFGFAQN ITPAELQFSQ YGSPEFVSPE
1260 1270 1280 1290 1300
IIQQNPVSEA SDIWAMGVIS YLSLTCSSPF AGESDRATLL NVLEGRVSWS
1310 1320 1330 1340 1350
SPMAAHLSED AKDFIKATLQ RAPQARPSAA QCLSHPWFLK SMPAEEAHFI
1360 1370 1380 1390 1400
NTKQLKFLLA RSRWQRSLMS YKSILVMRSI PELLRGPPDS PSLGVARHLC
1410 1420 1430 1440 1450
RDTGGSSSSS SSSDNELAPF ARAKSLPPSP VTHSPLLHPR GFLRPSASLP
1460 1470 1480 1490 1500
EEAEASERST EAPAPPASPE GAGPPAAQGC VPRHSVIRSL FYHQAGESPE
1510 1520 1530 1540 1550
HGALAPGSRR HPARRRHLLK GGYIAGALPG LREPLMEHRV LEEEAAREEQ
1560 1570 1580 1590 1600
ATLLAKAPSF ETALRLPASG THLAPGHSHS LEHDSPSTPR PSSEACGEAQ
1610 1620 1630 1640 1650
RLPSAPSGGA PIRDMGHPQG SKQLPSTGGH PGTAQPERPS PDSPWGQPAP
1660 1670 1680 1690 1700
FCHPKQGSAP QEGCSPHPAV APCPPGSFPP GSCKEAPLVP SSPFLGQPQA
1710 1720 1730 1740 1750
PPAPAKASPP LDSKMGPGDI SLPGRPKPGP CSSPGSASQA SSSQVSSLRV
1760 1770 1780 1790 1800
GSSQVGTEPG PSLDAEGWTQ EAEDLSDSTP TLQRPQEQAT MRKFSLGGRG
1810 1820 1830 1840 1850
GYAGVAGYGT FAFGGDAGGM LGQGPMWARI AWAVSQSEEE EQEEARAESQ
1860 1870 1880 1890 1900
SEEQQEARAE SPLPQVSARP VPEVGRAPTR SSPEPTPWED IGQVSLVQIR
1910 1920 1930 1940 1950
DLSGDAEAAD TISLDISEVD PAYLNLSDLY DIKYLPFEFM IFRKVPKSAQ
1960 1970 1980 1990 2000
PEPPSPMAEE ELAEFPEPTW PWPGELGPHA GLEITEESED VDALLAEAAV
2010 2020 2030 2040 2050
GRKRKWSSPS RSLFHFPGRH LPLDEPAELG LRERVKASVE HISRILKGRP
2060 2070 2080 2090 2100
EGLEKEGPPR KKPGLASFRL SGLKSWDRAP TFLRELSDET VVLGQSVTLA
2110 2120 2130 2140 2150
CQVSAQPAAQ ATWSKDGAPL ESSSRVLISA TLKNFQLLTI LVVVAEDLGV
2160 2170 2180 2190 2200
YTCSVSNALG TVTTTGVLRK AERPSSSPCP DIGEVYADGV LLVWKPVESY
2210 2220 2230 2240 2250
GPVTYIVQCS LEGGSWTTLA SDIFDCCYLT SKLSRGGTYT FRTACVSKAG
2260 2270 2280 2290 2300
MGPYSSPSEQ VLLGGPSHLA SEEESQGRSA QPLPSTKTFA FQTQIQRGRF
2310 2320 2330 2340 2350
SVVRQCWEKA SGRALAAKII PYHPKDKTAV LREYEALKGL RHPHLAQLHA
2360 2370 2380 2390 2400
AYLSPRHLVL ILELCSGPEL LPCLAERASY SESEVKDYLW QMLSATQYLH
2410 2420 2430 2440 2450
NQHILHLDLR SENMIITEYN LLKVVDLGNA QSLSQEKVLP SDKFKDYLET
2460 2470 2480 2490 2500
MAPELLEGQG AVPQTDIWAI GVTAFIMLSA EYPVSSEGAR DLQRGLRKGL
2510 2520 2530 2540 2550
VRLSRCYAGL SGGAVAFLRS TLCAQPWGRP CASSCLQCPW LTEEGPACSR
2560 2570 2580
PAPVTFPTAR LRVFVRNREK RRALLYKRHN LAQVR
Length:2,585
Mass (Da):282,124
Last modified:October 5, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7CA0151054ED9F16
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5VST9OBSCN_HUMAN
Obscurin
OBSCN KIAA1556, KIAA1639
7,968Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A6NGQ3A6NGQ3_HUMAN
Obscurin
OBSCN
8,923Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BQA7H3BQA7_HUMAN
Obscurin
OBSCN
1,593Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MRI8A0A0A0MRI8_HUMAN
Obscurin
OBSCN
858Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BPW6H3BPW6_HUMAN
Obscurin
OBSCN
68Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL353593 Genomic DNA No translation available.
AL359510 Genomic DNA No translation available.
AL670729 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000636476; ENSP00000489816; ENSG00000154358

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL353593 Genomic DNA No translation available.
AL359510 Genomic DNA No translation available.
AL670729 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Proteomic databases

jPOSTiA0A1B0GTS2
PeptideAtlasiA0A1B0GTS2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000636476; ENSP00000489816; ENSG00000154358

Organism-specific databases

HGNCiHGNC:15719 OBSCN
OpenTargetsiENSG00000154358

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000154756

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
OBSCN human

Gene expression databases

ExpressionAtlasiA0A1B0GTS2 baseline and differential

Family and domain databases

CDDicd00160 RhoGEF, 1 hit
cd12025 SH3_Obscurin_like, 1 hit
Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
2.60.40.10, 6 hits
InterProiView protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR011009 Kinase-like_dom_sf
IPR035526 Obscurin_SH3
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR015726 Ser/Thr_kin_striated-sp
IPR008271 Ser/Thr_kinase_AS
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR008266 Tyr_kinase_AS
PANTHERiPTHR45065 PTHR45065, 6 hits
PfamiView protein in Pfam
PF07679 I-set, 5 hits
PF00069 Pkinase, 2 hits
PF00621 RhoGEF, 1 hit
SMARTiView protein in SMART
SM00409 IG, 5 hits
SM00408 IGc2, 5 hits
SM00233 PH, 1 hit
SM00325 RhoGEF, 1 hit
SM00220 S_TKc, 2 hits
SUPFAMiSSF48065 SSF48065, 1 hit
SSF48726 SSF48726, 5 hits
SSF49265 SSF49265, 1 hit
SSF50044 SSF50044, 1 hit
SSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS50010 DH_2, 1 hit
PS50853 FN3, 1 hit
PS50835 IG_LIKE, 5 hits
PS50003 PH_DOMAIN, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 2 hits
PS00108 PROTEIN_KINASE_ST, 1 hit
PS00109 PROTEIN_KINASE_TYR, 1 hit
PS50002 SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1B0GTS2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1B0GTS2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: January 16, 2019
This is version 19 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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