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Protein

Putative hydroxypyruvate isomerase

Gene

HYI

Organism
Nothobranchius furzeri (Turquoise killifish)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).UniRule annotation

Catalytic activityi

Hydroxypyruvate = 2-hydroxy-3-oxopropanoate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei150Proton donor/acceptorUniRule annotation1
Active sitei249Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionIsomeraseUniRule annotationImported
LigandPyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Putative hydroxypyruvate isomeraseUniRule annotation (EC:5.3.1.22UniRule annotation)
Gene namesi
Name:HYIImported
OrganismiNothobranchius furzeri (Turquoise killifish)Imported
Taxonomic identifieri105023 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesNothobranchiidaeNothobranchius

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 218AP_endonuc_2InterPro annotationAdd BLAST194

Sequence similaritiesi

Belongs to the hyi family.UniRule annotation

Phylogenomic databases

KOiK01816

Family and domain databases

InterProiView protein in InterPro
IPR026040 HyI-like
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PIRSFiPIRSF006241 HyI, 1 hit
SUPFAMiSSF51658 SSF51658, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1A8V2L9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPLKFSANI SWLFSELPDF SQRMSAAAAA GFQAVEAAWL YDADLTELQR
60 70 80 90 100
AREAAGVEVV LINTPPGDVK AGDLGLAAVP GREGDFRQGL DQTLKYAKGL
110 120 130 140 150
NCKMIHLMAG RVPVDSHRHL VAKEMEAVFV QNLKYAADIL SKEGITGLIE
160 170 180 190 200
PINTRITDPR YFLDSPHQAA AILESVGKPN IKLQMDVFHW QIMDGNLTQN
210 220 230 240 250
MHKYFPLIGH VQVAQVPGRN EPDSDGELNY SYLFRTLEHL GYRGYIGCEY
260 270
KPFESTTKGL GWIQQYWTHG AQ
Length:272
Mass (Da):30,294
Last modified:October 5, 2016 - v1
Checksum:i977870A6AC82EC4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HAEJ01013355 Transcribed RNA Translation: SBS53812.1
RefSeqiXP_015817729.1, XM_015962243.1

Genome annotation databases

GeneIDi107387331
KEGGinfu:107387331

Similar proteinsi

Entry informationi

Entry nameiA0A1A8V2L9_NOTFU
AccessioniPrimary (citable) accession number: A0A1A8V2L9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: March 28, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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