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Entry version 10 (11 Dec 2019)
Sequence version 1 (05 Oct 2016)
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Protein

MIF4G domain-containing protein

Gene

CABZ01085054.1

Organism
Nothobranchius rachovii (bluefin notho)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
MIF4G domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CABZ01085054.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNothobranchius rachovii (bluefin notho)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri451742 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesNothobranchiidaeNothobranchius

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini844 – 1067MIF4GInterPro annotationAdd BLAST224

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 87DisorderedSequence analysisAdd BLAST87
Regioni178 – 315DisorderedSequence analysisAdd BLAST138
Regioni329 – 526DisorderedSequence analysisAdd BLAST198
Regioni539 – 608DisorderedSequence analysisAdd BLAST70
Regioni624 – 681DisorderedSequence analysisAdd BLAST58
Regioni765 – 790DisorderedSequence analysisAdd BLAST26
Regioni812 – 834DisorderedSequence analysisAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili946 – 977Sequence analysisAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi22 – 43Pro-richSequence analysisAdd BLAST22
Compositional biasi51 – 69PolarSequence analysisAdd BLAST19
Compositional biasi192 – 212PolyampholyteSequence analysisAdd BLAST21
Compositional biasi220 – 252PolarSequence analysisAdd BLAST33
Compositional biasi285 – 315PolarSequence analysisAdd BLAST31
Compositional biasi344 – 358Pro-richSequence analysisAdd BLAST15
Compositional biasi366 – 380PolyampholyteSequence analysisAdd BLAST15
Compositional biasi389 – 404PolarSequence analysisAdd BLAST16
Compositional biasi469 – 495PolarSequence analysisAdd BLAST27
Compositional biasi576 – 592PolarSequence analysisAdd BLAST17
Compositional biasi632 – 648Pro-richSequence analysisAdd BLAST17
Compositional biasi652 – 667PolyampholyteSequence analysisAdd BLAST16

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.180, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024, ARM-type_fold
IPR037584, EIF4G1
IPR016021, MIF4-like_sf
IPR003890, MIF4G-like_typ-3

The PANTHER Classification System

More...
PANTHERi
PTHR23253:SF10, PTHR23253:SF10, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02854, MIF4G, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00543, MIF4G, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

A0A1A8Q8N5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
PHPAPSPGLS QATFSPGQPP SVVFATPQPP QMNPTPQPRQ FAPVPRPIHQ
60 70 80 90 100
QGSFRSLQPY YTNRASLPPS SGPRGVPPSA PRPVTPTHVY QAGSQMMMIP
110 120 130 140 150
QQQLSFAGSP QGPAYFIPGQ YRSPTYVATP QQYQVPAGTP SFYQSTSPAE
160 170 180 190 200
YGTYAGAYYP AQPQFTPQVQ AAPVIMNPAP QQQQPPPQPS QHIHTKRERK
210 220 230 240 250
QIRIRDPNQG GRDITEEIMS GGRSGSTPTP PQTALSGSDS TVVPQANGES
260 270 280 290 300
ITAAATPVLV RSDDQGTRTP PLSQTPELAR AAPVPSETTT DTNTKAFTPP
310 320 330 340 350
PLSESKNTPP TTVSIPESCA LLADVMDAPL PPRGARLTPQ LAPEVPAYPA
360 370 380 390 400
PLPDPVPAHS AQNKPNKSGK EAKEEVMTEE GPEVENVDVS LEISNSQPSS
410 420 430 440 450
SNGVAEAVLE RPPITLTASH PEEPLESPIA QPEELRLPNG LPLPAPEDPE
460 470 480 490 500
APAVSMLEHD DSPIAEPDVS QQPVPTSSVP EAVKQTVTAS AVSAELSASA
510 520 530 540 550
MEDASPEEAT QSKPIQPGAQ ELAPEAVLDV KEEILVPQSI ATEETPFPAE
560 570 580 590 600
PLSVDDITPE TIPASPLPPA EEKEDSPPTQ TVTPTPVETS MQAAVSVPKK
610 620 630 640 650
KRKMKDLNKK EAVGDLLDAF KEEQVVVRAE PEPAPAPEPK PPAASPPVPE
660 670 680 690 700
EADLTWEDKE DKLDAENIQP DPQQPSATDM KYQYKEDQWK PINTEEKKKY
710 720 730 740 750
DREFLLGFQF ISASMNKPEG LPAISDVVLD RANKTPLRQL DPTRLSGMNC
760 770 780 790 800
GPDFTPSFAN LGRPGMGGGG GRGLPPGMGG PRHSQQVPRK EQRKIITSMS
810 820 830 840 850
LSDDVQLNKA EKAWKPSVKK PTQSRVGETF DENDPEQVKT QELFKRVRSI
860 870 880 890 900
LNKLTPQKFQ QLMKQVQELT VDTEERLKGV IDLTFEKAIS EPDFSVAYAN
910 920 930 940 950
MCRCLSGLKV LTPDKPGITV NFRKLLLNRC QKEFEKDKDD DEIFEKKQKE
960 970 980 990 1000
LEAASVEEEK QRLVEELAEA KDKARRRSMG NIKFIGELFK LKMLTEVIMH
1010 1020 1030 1040 1050
DCILKLLKNH DEESLECLCR LLSTIGKDLD FEKAKPRMDQ YFNQMEKIIK
1060
ERKTTSRIRF MLQDVLD
Length:1,067
Mass (Da):116,767
Last modified:October 5, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0DB82D633AABA57B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei1067Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
HAEH01010388 Transcribed RNA Translation: SBR89564.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HAEH01010388 Transcribed RNA Translation: SBR89564.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di1.25.40.180, 1 hit
InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR037584, EIF4G1
IPR016021, MIF4-like_sf
IPR003890, MIF4G-like_typ-3
PANTHERiPTHR23253:SF10, PTHR23253:SF10, 1 hit
PfamiView protein in Pfam
PF02854, MIF4G, 1 hit
SMARTiView protein in SMART
SM00543, MIF4G, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1A8Q8N5_9TELE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1A8Q8N5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: December 11, 2019
This is version 10 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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