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Protein
Submitted name:

Nerve growth factor receptor

Gene

NGFR

Organism
Nothobranchius kuhntae (Beira killifish)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Nerve growth factor receptorImported
Gene namesi
Name:NGFRImported
OrganismiNothobranchius kuhntae (Beira killifish)Imported
Taxonomic identifieri321403 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesNothobranchiidaeNothobranchius

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei263 – 283HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 38Sequence analysisAdd BLAST38
ChainiPRO_500837198739 – 368Sequence analysisAdd BLAST330

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi61 ↔ 74PROSITE-ProRule annotation
Disulfide bondi103 ↔ 116PROSITE-ProRule annotation
Disulfide bondi106 ↔ 124PROSITE-ProRule annotation
Disulfide bondi142 ↔ 155PROSITE-ProRule annotation
Disulfide bondi145 ↔ 163PROSITE-ProRule annotation
Disulfide bondi166 ↔ 181PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 81TNFR-CysInterPro annotationAdd BLAST34
Repeati48 – 81TNFR-CysPROSITE-ProRule annotationAdd BLAST34
Domaini83 – 124TNFR-CysInterPro annotationAdd BLAST42
Repeati83 – 124TNFR-CysPROSITE-ProRule annotationAdd BLAST42
Domaini125 – 163TNFR-CysInterPro annotationAdd BLAST39
Repeati125 – 163TNFR-CysPROSITE-ProRule annotationAdd BLAST39
Domaini165 – 207TNFR-CysInterPro annotationAdd BLAST43
Repeati165 – 207TNFR-CysPROSITE-ProRule annotationAdd BLAST43

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

CDDicd13416 TNFRSF16, 1 hit
InterProiView protein in InterPro
IPR001368 TNFR/NGFR_Cys_rich_reg
IPR022325 TNFR_16
IPR034046 TNFRSF16_N
PfamiView protein in Pfam
PF00020 TNFR_c6, 3 hits
PRINTSiPR01966 TNFACTORR16
SMARTiView protein in SMART
SM00208 TNFR, 4 hits
PROSITEiView protein in PROSITE
PS00652 TNFR_NGFR_1, 1 hit
PS50050 TNFR_NGFR_2, 4 hits

Sequencei

Sequence statusi: Fragment.

A0A1A8IGK7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
QRCILRSRAV LCDSSRRSRM TAKLSLIILC AMVTLARTSK TERALFPDCS
60 70 80 90 100
SGRYTDGGEC CLECPPGEGV VKECGATQTV CAQCLDSETF SENDSHTEKC
110 120 130 140 150
KPCTQCTGLM RMETPCTDSN DAKCVCNYNY YYNKLSGQCE LCTVCPVGQG
160 170 180 190 200
VYSHCDHHHD TVCEECVDET YSDRESSLEP CLPCTICDEE MDETLIAECT
210 220 230 240 250
PNSDSVCHNP NLPTYDPTIA DPLTYSDAIF PGGSDNPLPN GETTTSSAGS
260 270 280 290 300
PRFLGHGLNE NLIPIYCSIL AAVVVGLVAY IVFKRWNSCK QNKQAANNRA
310 320 330 340 350
ATNNQMVTPE GEKLHSDSGI SVDTQSLQEQ QQQAQAEVQP QPSRTHTQEQ
360
IVVSVDGGPH PDSPPPEV
Length:368
Mass (Da):40,074
Last modified:October 5, 2016 - v1
Checksum:i9649988E5F82D2FD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HAED01010054 Transcribed RNA Translation: SBQ96266.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HAED01010054 Transcribed RNA Translation: SBQ96266.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd13416 TNFRSF16, 1 hit
InterProiView protein in InterPro
IPR001368 TNFR/NGFR_Cys_rich_reg
IPR022325 TNFR_16
IPR034046 TNFRSF16_N
PfamiView protein in Pfam
PF00020 TNFR_c6, 3 hits
PRINTSiPR01966 TNFACTORR16
SMARTiView protein in SMART
SM00208 TNFR, 4 hits
PROSITEiView protein in PROSITE
PS00652 TNFR_NGFR_1, 1 hit
PS50050 TNFR_NGFR_2, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1A8IGK7_NOTKU
AccessioniPrimary (citable) accession number: A0A1A8IGK7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: April 12, 2017
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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