Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

RuvB-like helicase

Gene

RUVBL1

Organism
Nothobranchius furzeri (Turquoise killifish)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotationSAAS annotation, Hydrolase
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, Transcription, Transcription regulationUniRule annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RuvB-like helicaseUniRule annotation (EC:3.6.4.12UniRule annotation)
Gene namesi
Name:RUVBL1Imported
OrganismiNothobranchius furzeri (Turquoise killifish)Imported
Taxonomic identifieri105023 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesNothobranchiidaeNothobranchius

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 352AAAInterPro annotationAdd BLAST291

Sequence similaritiesi

Belongs to the RuvB family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK04499

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR027417 P-loop_NTPase
IPR027238 RuvB-like
IPR037938 RUVBL1
IPR010339 TIP49_C
PANTHERiPTHR11093 PTHR11093, 1 hit
PTHR11093:SF6 PTHR11093:SF6, 1 hit
PfamiView protein in Pfam
PF06068 TIP49, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits

Sequencei

Sequence statusi: Complete.

A0A1A7ZQ69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIEEVKSTT KTQRIASHSH VKGLGLDEAG NAKSTACGLV GQEAAREACG
60 70 80 90 100
IIVEMIRSKK MAGRAVLLAG PPGTGKTALA LAVAQELGNK VPFCPMVGSE
110 120 130 140 150
VYSTEIKKTE VLMENFRRAI GLRIKETKEV YEGEVTELTP CETENPMGGY
160 170 180 190 200
GKTISHVIIG LKTAKGTKQL KLDPSIYESL QKERVEVGDV IYIEANSGAV
210 220 230 240 250
KRQGRCDTFA TEFDLEAEEY VPLPKGDVHK KKEIVQDVTL HDLDVANARP
260 270 280 290 300
QGGQDILSMM GQLMKPKKTE ITDKLRTEIN KVVNRYIDQG VAELVPGVLF
310 320 330 340 350
VDEVHMLDIE CFTYLHRALE SSIAPIVVFA SNRGNCLIRG TEDISSPHGI
360 370 380 390 400
PLDLLDRVMI IRTMMYTPQE MKQIIKIRAQ TEGINVSEEA LTHLAEIGTK
410 420 430 440 450
TTLRYAVQLL TPASLLGRVQ GKETVEREQV EEINELFYDA KSSAKILQDQ

HHKFMK
Length:456
Mass (Da):50,414
Last modified:October 5, 2016 - v1
Checksum:i15E45B91737CAE76
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HADY01005660 Transcribed RNA Translation: SBP44145.1
HAEJ01005654 Transcribed RNA Translation: SBS46111.1
RefSeqiXP_015815267.1, XM_015959781.1

Genome annotation databases

GeneIDi107385709
KEGGinfu:107385709

Similar proteinsi

Entry informationi

Entry nameiA0A1A7ZQ69_NOTFU
AccessioniPrimary (citable) accession number: A0A1A7ZQ69
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: March 28, 2018
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health