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Protein

Cystathionine beta-synthase

Gene

A6R68_04618

Organism
Neotoma lepida (Desert woodrat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

L-serine + L-homocysteine = L-cystathionine + H2O.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation
Biological processAmino-acid biosynthesis, Cysteine biosynthesisUniRule annotation
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Cystathionine beta-synthaseUniRule annotation (EC:4.2.1.22UniRule annotation)
Gene namesi
ORF Names:A6R68_04618Imported
OrganismiNeotoma lepida (Desert woodrat)Imported
Taxonomic identifieri56216 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeNeotominaeNeotoma
Proteomesi
  • UP000092124 Componenti: Unassembled WGS sequence

Subcellular locationi

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini414 – 474CBSInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the cysteine synthase/cystathionine beta-synthase family.UniRule annotation

Keywords - Domaini

CBS domainPROSITE-ProRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR000644 CBS_dom
IPR005857 Cysta_beta_synth
IPR001216 P-phosphate_BS
IPR001926 PLP-dep
IPR036052 Trypto_synt_PLP_dependent
PfamiView protein in Pfam
PF00571 CBS, 1 hit
PF00291 PALP, 1 hit
SMARTiView protein in SMART
SM00116 CBS, 1 hit
SUPFAMiSSF53686 SSF53686, 1 hit
TIGRFAMsiTIGR01137 cysta_beta, 1 hit
PROSITEiView protein in PROSITE
PS51371 CBS, 1 hit
PS00901 CYS_SYNTHASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1A6GNB5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSGTSQCED GSAVCPQHLD RHSGKGHTEK GPSGDNERLW IRPDTPSKCT
60 70 80 90 100
WQLGRPMADS PHHHTTLTES PKILPDILWK IGNTPMVRIN KISKNAGLKC
110 120 130 140 150
ELLAKCEFFN AGGSVKDRIS LRMIEDAERA GTLKPGDTII EPTSGNTGIG
160 170 180 190 200
LALAAAVKGY RCIIVMPEKM SMEKVDVLRA LGAEIVRTPT NARFDSPESH
210 220 230 240 250
VGVAWRLKNE IPNSHILDQY RNASNPLAHY DDTAXEILQQ CDGKLDMLVA
260 270 280 290 300
SAGTGGTITG IARKLKEKCP GCKIIGVDPE GSILAEPEEL NQTEQTAYEV
310 320 330 340 350
EGIGYDFVPT VLDRAVVDKW FKSNDEESFA FARMLIAQEG LLCGGSSGSA
360 370 380 390 400
MAVAXKAAQE LQEGQRCVVI LPDSVRNYMS KFLSDKWMLQ KGFMKEELSV
410 420 430 440 450
KRPWWWHLRV QELSLSAPLT VLPTVTCEHT ITILREKGFD QAPVVDESGA
460 470 480 490 500
ILGMVTLGNM LSSLLAGKVQ PSDEVCKVLY KQFKPIHLTD TLGMLSHILE
510 520 530 540 550
MDHFALVIHE QIQSRDQAWS GVVGGPTDDS NGMSSELQMV FGVVTAIDLL
560
NFVAARERNQ K
Length:561
Mass (Da):61,521
Last modified:October 5, 2016 - v1
Checksum:iDEB23597D509F601
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LZPO01087178 Genomic DNA Translation: OBS66847.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LZPO01087178 Genomic DNA Translation: OBS66847.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiView protein in InterPro
IPR000644 CBS_dom
IPR005857 Cysta_beta_synth
IPR001216 P-phosphate_BS
IPR001926 PLP-dep
IPR036052 Trypto_synt_PLP_dependent
PfamiView protein in Pfam
PF00571 CBS, 1 hit
PF00291 PALP, 1 hit
SMARTiView protein in SMART
SM00116 CBS, 1 hit
SUPFAMiSSF53686 SSF53686, 1 hit
TIGRFAMsiTIGR01137 cysta_beta, 1 hit
PROSITEiView protein in PROSITE
PS51371 CBS, 1 hit
PS00901 CYS_SYNTHASE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1A6GNB5_NEOLE
AccessioniPrimary (citable) accession number: A0A1A6GNB5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: March 28, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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