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Protein

EEF1A lysine methyltransferase 1

Gene

EEF1AKMT1

Organism
Neotoma lepida (Desert woodrat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported
Was originally thought to be an N6-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
EEF1A lysine methyltransferase 1UniRule annotation (EC:2.1.1.-UniRule annotation)
Alternative name(s):
N(6)-adenine-specific DNA methyltransferase 2UniRule annotation
Protein-lysine N-methyltransferase N6AMT2UniRule annotation
Gene namesi
Name:EEF1AKMT1UniRule annotation
Synonyms:N6AMT2UniRule annotation
ORF Names:A6R68_09071Imported
OrganismiNeotoma lepida (Desert woodrat)Imported
Taxonomic identifieri56216 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeNeotominaeNeotoma
Proteomesi
  • UP000092124 Componenti: Unassembled WGS sequence

Subcellular locationi

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.UniRule annotation

Family and domain databases

HAMAPiMF_03187 Methyltr_EFM5, 1 hit
InterProiView protein in InterPro
IPR002052 DNA_methylase_N6_adenine_CS
IPR019369 Efm5/EEF1AKMT1
IPR029063 SAM-dependent_MTases
SUPFAMiSSF53335 SSF53335, 1 hit
PROSITEiView protein in PROSITE
PS00092 N6_MTASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1A6G1X7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDSEDDDIP QLSSHALAAL QEFYAEQKQS INPGGDDKYN VGVIEENWQL
60 70 80 90 100
SQFWYSQDTA LRLAQEVIAA AGEGGRIACV SAPSVYQKLR ELXGEAISAH
110 120 130 140 150
IFEYDRRFAI YGEQFVFYDY NNPLDLPGRI AEHSFDIVVA DPPYLSEECL
160 170 180 190 200
RKTSETIRFL TQGKVLLCTG AIMEEQAAQL LGVKMCKFIP EHSRNLANEF
210
RCYTNYDSGL DYET
Length:214
Mass (Da):24,187
Last modified:October 5, 2016 - v1
Checksum:i0109645D65F475F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LZPO01107954 Genomic DNA Translation: OBS59810.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LZPO01107954 Genomic DNA Translation: OBS59810.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

HAMAPiMF_03187 Methyltr_EFM5, 1 hit
InterProiView protein in InterPro
IPR002052 DNA_methylase_N6_adenine_CS
IPR019369 Efm5/EEF1AKMT1
IPR029063 SAM-dependent_MTases
SUPFAMiSSF53335 SSF53335, 1 hit
PROSITEiView protein in PROSITE
PS00092 N6_MTASE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1A6G1X7_NEOLE
AccessioniPrimary (citable) accession number: A0A1A6G1X7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: December 20, 2017
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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