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Protein

Histone deacetylase

Gene

METBIDRAFT_30163

Organism
Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorSAAS annotation, HydrolaseSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseSAAS annotation (EC:3.5.1.98SAAS annotation)
Gene namesi
ORF Names:METBIDRAFT_30163Imported
OrganismiMetschnikowia bicuspidata var. bicuspidata NRRL YB-4993Imported
Taxonomic identifieri869754 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesMetschnikowiaceaeMetschnikowia
Proteomesi
  • UP000092555 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini94 – 404Hist_deacetylInterPro annotationAdd BLAST311
Domaini465 – 696Arb2InterPro annotationAdd BLAST232

Family and domain databases

Gene3Di3.40.800.20, 1 hit
InterProiView protein in InterPro
IPR019154 Arb2_domain
IPR000286 His_deacetylse
IPR023801 His_deacetylse_dom
IPR037138 His_deacetylse_dom_sf
IPR017321 Hist_deAcase_II_yeast
IPR023696 Ureohydrolase_dom_sf
PANTHERiPTHR10625 PTHR10625, 1 hit
PfamiView protein in Pfam
PF09757 Arb2, 1 hit
PF00850 Hist_deacetyl, 1 hit
PIRSFiPIRSF037919 HDAC_II_yeast, 1 hit
PRINTSiPR01270 HDASUPER
SUPFAMiSSF52768 SSF52768, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1A0HHW6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDAPRADASY IKNGTSPFLD EPAVKREHVE DDNVLPVENG AKKQKADPAA
60 70 80 90 100
PMVVVPHKKP HLFYSPLKTG IVYDVRMRYH AKIFTLYFEY IDPHPEDPRR
110 120 130 140 150
IYRIYKRLAE AGLIQDTSLL GSNDIGPLMV KIPIREASEE EILQVHTENH
160 170 180 190 200
LRYIQQTETM TRDQLLEETE KGDSIYVNND SFLLAKLSCG GLIEACRAVV
210 220 230 240 250
EGTVKNLLAI VRPPGHHAEP NAPGGFCLFS NVAVAAKNML RMYPESVRRI
260 270 280 290 300
VIVDWDIHHG NGTQRAFYDD PRVLYISLHR FENGRFYPGT KYGGADMVGK
310 320 330 340 350
GKGEGFSVNV PWQDAGVGDA DYMHAFHRVV LPIVSEFDPD LVIVSSGFDA
360 370 380 390 400
ADGDIIGQCH VTPAGYGQLT HMLKAVARGK LTVILEGGYN LDAISHSALG
410 420 430 440 450
VAKVLVGEPP EATVTTQPRL DTLETVSEVV RIQAKYWRSM RPGNAARLFE
460 470 480 490 500
DAYDVAGAPL LSLAEPMRAY QAQKLFQTFG FIGLPVLAAT DAKLPLFTTD
510 520 530 540 550
LPAHLEDLVL ASRDIGTCGT VVVLVHDPPE VWANVNPVSG NIESNSSVVL
560 570 580 590 600
EHPLPKLIRT VQKELEGDGE NARLGFIDIN VPSFTDAVAA NGLARLGDYN
610 620 630 640 650
ATIFAQELLL WVWDHYLCYF QQLKKVVFVG YGDAYQAIVH LYAKRPPQEI
660 670 680 690 700
RDLVQGTVVF ANRTTLRPIV PVMDESMVDW FYQNSVVFTS PMNPCWMGAT
710 720 730 740 750
GKPEGEESSR RPRKKFGRVL RASADGLWEV INEKFDEGVD FILDSVSDYS

GSESA
Length:755
Mass (Da):83,676
Last modified:October 5, 2016 - v1
Checksum:iEC9F13EDEE400E16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LXTC01000001 Genomic DNA Translation: OBA23754.1
RefSeqiXP_018714235.1, XM_018855569.1

Genome annotation databases

EnsemblFungiiOBA23754; OBA23754; METBIDRAFT_30163
GeneIDi30028545

Similar proteinsi

Entry informationi

Entry nameiA0A1A0HHW6_9ASCO
AccessioniPrimary (citable) accession number: A0A1A0HHW6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: May 23, 2018
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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