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UniProtKB - A0A194RCI7 (A0A194RCI7_PAPMA)

Entry version 11 (02 Dec 2020)
Sequence version 1 (05 Oct 2016)
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Protein
Submitted name:

Integrator complex subunit 2

Gene

RR48_09211

Organism
Papilio machaon (Old World swallowtail butterfly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Integrator complex subunit 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:RR48_09211Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPapilio machaon (Old World swallowtail butterfly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri76193 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Lepidoptera › Glossata › Ditrysia › Papilionoidea › Papilionidae › Papilioninae › Papilio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000053240 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Integrator subunit 2 family.ARBA annotation

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR026236, Int2_metazoa
IPR029321, INTS2

The PANTHER Classification System

More...PANTHERi		PTHR28608, PTHR28608, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF14750, INTS2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR02105, INTSUBUNIT2

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A194RCI7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPCFLKPVQ PHIFKAIKDI DIDVLVKSSP DEIRPIIPCL VRMALISPLD 
        60         70         80         90        100
VTQYCAEAKK EILTLLSGID LVNFIVSLLS IEFHTLEVDL KKEQQIRQKS 
       110        120        130        140        150
GTQTTESFLI PNPVNGISND FEQSDSARRV RLVLSEILQM QAQIVEYQQN 
       160        170        180        190        200
RHTNNDCSVK PSELFDNDVY LEEITDVICI SLAELPNLLN ISDIVEVLLH 
       210        220        230        240        250
VNKGPVIVSW VVANMPDTLY EVAESLVVNA ERGEEGGIRA KALMSLCAMC 
       260        270        280        290        300
PYLSATVRAK AVSASRLPAL VLNLTLTHHQ DDLVSFMSGL LLGSDQSTRG 
       310        320        330        340        350
WFATFLRNSH KRGKGDGNAA LIKLRQELLK RLKDASAGVE ASALLRLYCA 
       360        370        380        390        400
LRGIAGIKFQ DDEVSGLLRL VTQKPPPTPA GVRFVSLSLC MILACPSLMT 
       410        420        430        440        450
AADHEKKAIE WVQWLVKEEA YFESNSGVTA SFGEMLLLIA IHFHSGQLAA 
       460        470        480        490        500
VGELVCATLG MRVPVRPNGL ARIKQAFTQE IFTEQVVTAH AVKVPVTANL 
       510        520        530        540        550
NGNIPGYLPV HCIHQLLKSR AFSKHKVPIK NWIYKQICNC TAPLHPVMPA 
       560        570        580        590        600
LVEVYVSSIL VINNKGNSEY VNKPITEEEI RKVFRNSIFG VNFDQQNKGF 
       610        620        630        640        650
SPMEIDNGES SVDIRIEKPT LASQLLLIYY LLLYEDIRLS NTATLIANGR 
       660        670        680        690        700
KIKSYSAAFL SELPIKYLLH QAQKDQMSYG VLFSPLLRLL ATHFPQLSLV 
       710        720        730        740        750
DDWMDDQVFG DSCRHQIDVE LSESSINEAF QCIEENPYKT GKVLKAMLSK 
       760        770        780        790        800
NPTDIWPFAE IFVKYFKSVL SDQVPRHIQE LYREVWLRLN TVLPRCLWIM 
       810        820        830        840        850
TINALLDING NGRNVTITQE NVLVDPLQVL RCDIRVFRCG PILKIILRIL 
       860        870        880        890        900
EASLAASRSQ LSRHLLDKPL LEKSGQLTSD SEREELKNAL VAAQESAALQ 
       910        920        930        940        950
ILLEACLETS EDQSKPELMW SLREVRSIIC SFLHQVFISE PSLAKLVHFQ 
       960        970        980        990       1000
GYPRELLPVT IQGIPSMHIC LDFIPELLSQ ASLEKQIFAV DLVSHLSIQY 
      1010       1020       1030       1040       1050
ALPKAMSIAR LCVNTLSTLL SVLPSDLRLE LFQPILKSLV RICTAFPSLL 
      1060       1070       1080       1090       1100
EDITSLLLQL GRICESQASL GHCWNDTNIL GEGAYVSSDV QSDTKVLVAE 
      1110       1120 
VLCRDIKVTM SEIVQKALLN DKLY
Length:1,124
Mass (Da):125,579
Last modified:October 5, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC708CB347000DB35
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
KQ460398 Genomic DNA Translation: KPJ15184.1

NCBI Reference Sequences

More...RefSeqi		XP_014358467.1, XM_014502981.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		106710812

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		pmac:106710812

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KQ460398 Genomic DNA Translation: KPJ15184.1
RefSeqiXP_014358467.1, XM_014502981.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

GeneIDi106710812
KEGGipmac:106710812

Family and domain databases

InterProiView protein in InterPro
IPR026236, Int2_metazoa
IPR029321, INTS2
PANTHERiPTHR28608, PTHR28608, 1 hit
PfamiView protein in Pfam
PF14750, INTS2, 1 hit
PRINTSiPR02105, INTSUBUNIT2

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A194RCI7_PAPMA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A194RCI7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 5, 2016
Last sequence update: October 5, 2016
Last modified: December 2, 2020
This is version 11 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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