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Protein

Calcium-transporting ATPase

Gene
N/A
Organism
Schistosoma curassoni
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

ATP + H2O + Ca2+(Side 1) = ADP + phosphate + Ca2+(Side 2).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processCalcium transportUniRule annotation, Ion transport, Transport
LigandATP-bindingUniRule annotation, Calcium, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Calcium-transporting ATPaseUniRule annotation (EC:3.6.3.8UniRule annotation)
OrganismiSchistosoma curassoniImported
Taxonomic identifieri6186 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma
Proteomesi
  • UP000050789 Componenti: Genome assembly

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 39HelicalUniRule annotationAdd BLAST20
Transmembranei59 – 86HelicalUniRule annotationAdd BLAST28
Transmembranei534 – 555HelicalUniRule annotationAdd BLAST22
Transmembranei567 – 586HelicalUniRule annotationAdd BLAST20
Transmembranei607 – 630HelicalUniRule annotationAdd BLAST24
Transmembranei702 – 721HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini558 – 761Cation_ATPase_CInterPro annotationAdd BLAST204

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Family and domain databases

Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR006068 ATPase_P-typ_cation-transptr_C
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR005782 P-type_ATPase_IIA
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00689 Cation_ATPase_C, 1 hit
SUPFAMiSSF56784 SSF56784, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 1 hit
TIGRFAMsiTIGR01116 ATPase-IIA1_Ca, 1 hit
TIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A183K1S0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMFRLNDSGV YLQQHKRISL SDSLFKLVIS IICVAVWAIN IGHFNDPAHG
60 70 80 90 100
GSWLKGAIYY FKIAVALAVA AIPEGLPAVI TTCLALGTRR MAAKNAIVRS
110 120 130 140 150
LPSVETLGCT SVICSDKTGT LTTNQMSVCR MFIFSKADDK APEVHHFEIT
160 170 180 190 200
GSKYAPEGEV FLNGQKVESG EYDGLVEIAN ICAMCNDSAI DYNESKHVYE
210 220 230 240 250
KVGEATETAL CCLVEKMNVY KTSKSGLSKK DLSMACNHQI QAMWNKEFTL
260 270 280 290 300
EFSRDRKSMS VYLQAKPAFS SKVPATAGSG ETGPRMFVKG APEGVLDRCT
310 320 330 340 350
FVRIGNKKVP MTPALKAEIV KHVASYGTGR DTLRCLALAT CDAPVSKAQM
360 370 380 390 400
DLEDSTKFVK YEQNLTFVGV VGMLDPPRME VFDSIARCRK SGIRVIMITG
410 420 430 440 450
DNKATAEAIC RRIGIFGEDE PTTGKSFTGR EFDALPIEEQ REACRRARLF
460 470 480 490 500
ARVEPMHKSK IVEFLQEDGE VSAMTGDGVN DAPALKKAEI GIAMGSGTAV
510 520 530 540 550
AKSAADMVLA DDNFNSIVLA VEEGRAIYNN MKQFIRYLIS SNIGEVVSIF
560 570 580 590 600
LTAALGLPEA LIPVQLLWVN LVTDGLPATA LGFNPPDLDI MERPPRNIKD
610 620 630 640 650
PLISGWLFFR YVAIGVYVGC ATVGAAAWWF SLYPKGPQLN YYQLTHQSQC
660 670 680 690 700
LAQESRFEGV DCSIFSHPKP MTMALSVLVL IEMLNAMNSL SENQSLVAMP
710 720 730 740 750
PWVNIWLVLA MVVSMSLHFL ILEVDFLSKV FQITPLSLEE WFMVVKISAP
760 770
VIFIDEILKL IARRFTDVPA NIGELK
Length:776
Mass (Da):85,279
Last modified:September 7, 2016 - v1
Checksum:i1FFCF5861E6B3AC7
GO

Genome annotation databases

WBParaSiteiSCUD_0000893301-mRNA-1; SCUD_0000893301-mRNA-1; SCUD_0000893301

Similar proteinsi

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

WBParaSiteiSCUD_0000893301-mRNA-1; SCUD_0000893301-mRNA-1; SCUD_0000893301

Family and domain databases

Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR006068 ATPase_P-typ_cation-transptr_C
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR005782 P-type_ATPase_IIA
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00689 Cation_ATPase_C, 1 hit
SUPFAMiSSF56784 SSF56784, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 1 hit
TIGRFAMsiTIGR01116 ATPase-IIA1_Ca, 1 hit
TIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A183K1S0_9TREM
AccessioniPrimary (citable) accession number: A0A183K1S0
Entry historyiIntegrated into UniProtKB/TrEMBL: September 7, 2016
Last sequence update: September 7, 2016
Last modified: November 7, 2018
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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