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Entry version 23 (07 Oct 2020)
Sequence version 1 (07 Sep 2016)
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Protein
Submitted name:

Uncharacterized protein

Gene

RP20_CCG000451

Organism
Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:RP20_CCG000451Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAedes albopictus (Asian tiger mosquito) (Stegomyia albopicta)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7160 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000249989 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000069940 Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Keywords - Cellular componenti

    NucleusARBA annotation

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini21 – 70PHD-typeInterPro annotationAdd BLAST50
    Domaini1811 – 1997Integrase catalyticInterPro annotationAdd BLAST187

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni145 – 272DisorderedSequence analysisAdd BLAST128
    Regioni681 – 703DisorderedSequence analysisAdd BLAST23

    Coiled coil

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili81 – 131Sequence analysisAdd BLAST51

    Compositional bias

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi193 – 211PolarSequence analysisAdd BLAST19
    Compositional biasi239 – 271PolarSequence analysisAdd BLAST33

    Keywords - Domaini

    Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

    Family and domain databases

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    3.30.40.10, 1 hit
    3.30.420.10, 1 hit
    3.30.70.270, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR043502, DNA/RNA_pol_sf
    IPR005312, DUF1759
    IPR040676, DUF5641
    IPR001584, Integrase_cat-core
    IPR008042, Retrotrans_Pao
    IPR043128, Rev_trsase/Diguanyl_cyclase
    IPR012337, RNaseH-like_sf
    IPR036397, RNaseH_sf
    IPR019786, Zinc_finger_PHD-type_CS
    IPR011011, Znf_FYVE_PHD
    IPR001965, Znf_PHD
    IPR019787, Znf_PHD-finger
    IPR013083, Znf_RING/FYVE/PHD

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF03564, DUF1759, 1 hit
    PF18701, DUF5641, 1 hit
    PF05380, Peptidase_A17, 1 hit

    Simple Modular Architecture Research Tool; a protein domain database

    More...
    SMARTi
    View protein in SMART
    SM00249, PHD, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF53098, SSF53098, 1 hit
    SSF56672, SSF56672, 1 hit
    SSF57903, SSF57903, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS50994, INTEGRASE, 1 hit
    PS01359, ZF_PHD_1, 1 hit
    PS50016, ZF_PHD_2, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    A0A182G158-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MANPDQVANN SDPATPANNQ TTDCMCCDRP ESIDDCVQCD QCSGWWHMTC
    60 70 80 90 100
    AEVTTSVADR SWTCSHCLPM SASSRTTTSS VRAARLALKK QQLEEQQAME
    110 120 130 140 150
    QRHLAEKYKL LQEELNEIDE TSSNRSRISR RTSLYKVKQW QQKCAEQTDG
    160 170 180 190 200
    AQGLPPMGSP TEPVAVPPAS RMDSREDGLM PSVDMSNIIA SKLPPVGPNT
    210 220 230 240 250
    QAQSDASQGK LLSERVPQGE AINNDRRNTV ATEGHRGYSF HQPSLNSTVK
    260 270 280 290 300
    APSYPEPSRA LKNQQQHTGA IPKVVPKQKE VADAVGKTLP HEIPVAQGKP
    310 320 330 340 350
    PHDPISDQFI PPKFENSLQH ITKQFGSLAP SAMVSSFHVY GANTHLPSET
    360 370 380 390 400
    SIGITPSANP MLSSGSAPSS MGLPNVGHGP HVNPVLPTGQ VPPPPGLAQA
    410 420 430 440 450
    GHLPQVNPVL STGQVPPTSG LAHNGYLPQV NPAQFCGQVP LSLRLSQVGH
    460 470 480 490 500
    LLHATPVLPT GQVPPPSGLP QILSVGQVPP SSGLPLVDQF TPSPSQLAAR
    510 520 530 540 550
    QVMSRDLPTF SGDPADWPIF ISTFMNSSLS CGFNSAENLA RLQRCLKGPA
    560 570 580 590 600
    YESVKSRLLL PESVPQVIDT LRLLYGRPEL LINALLQKVR SVPAPKAEKL
    610 620 630 640 650
    ETIIDFGMAV RSLCDHLEAA GQREHLSNPT LLMELVEKLP AHTKMQWADY
    660 670 680 690 700
    MQLHPVVNLK AFGDFMFGVI TAVSRVTMYT GGSSDSQHKA KQKGTINAHT
    710 720 730 740 750
    SETSDIREPV REIVRERVCV CCKKPWHRLA ECSIFKSYTV DERWKFAQNN
    760 770 780 790 800
    GLCRSCLNAH GRRSCKNAMQ CVIEGCHYRH HPLLHSNQPN ASSQSLQPLS
    810 820 830 840 850
    TAQNHMHRRY KPALLFRVIP VIISGPRTTV ETFAFLDDGS DLSLIETSLV
    860 870 880 890 900
    RQLGIEGSKK PLCLKWTGNV TRIESESKHV SIVVKGVSGQ QEFSLNDVRT
    910 920 930 940 950
    VEELTLPEQS LEYDDLSQQY HYLKGLPVVS YNKAVPRLLI GVNNANLTVP
    960 970 980 990 1000
    LKVREGKKGE PIAVKTRLGW CIFGGCGEKV THSLNYHTCE CSNDQELHNI
    1010 1020 1030 1040 1050
    VKEYFTMEDA GVKLPEMLKS EEDKRARRIL EETTVRVGGR FQTGLLWKYD
    1060 1070 1080 1090 1100
    TVEFPDSYNM AVKRFECLER KMVRDPELAV NLKNQISEYQ TKGYAHRATR
    1110 1120 1130 1140 1150
    EELVQADPKR VWYLPLGVVT NPRKPGKVRL IWDAAAKVDG IALNSMLLKG
    1160 1170 1180 1190 1200
    PDQLVSLPAV LSRFRQFKVG VSADIREMFH QLQIRETDRH SQRFLFRDDP
    1210 1220 1230 1240 1250
    SKPIEIYLMD VATFGSTCSP ASAQYVKNKN AEEFLDIFPR AAEGIIENHY
    1260 1270 1280 1290 1300
    VDDYLDSFED DEEAERVSNE IRSIHQRGGF ELRNWLSNSE KVLRGLNEED
    1310 1320 1330 1340 1350
    PKASKSLCLN TVDSSDRVLG MLWHTAEDEL RFSMKMKEEV QLVLDSGKRP
    1360 1370 1380 1390 1400
    TKRQMLRCLM GIFDPLGLLS VFLVHGKILL QDVWRSGLQW DEMVSGDIFE
    1410 1420 1430 1440 1450
    RWRRWTGLFP KIGELHVPRC YFKQATVRTY EQLQLHVFVD ASEAAFAAVA
    1460 1470 1480 1490 1500
    YFRVINDNGE PECSIVAAKT KVAPLKPLSI PRLELQAAVL GSRLLSFVQE
    1510 1520 1530 1540 1550
    SHSVKFKKRF LWSDSATVLA WLRADHRRYK QYVACRIGEL LSATDVAEWR
    1560 1570 1580 1590 1600
    WVPSNLNPAD AATKWGKNAC PDVNNEWFRG PKFLGDSEEN WPKQAQQSMN
    1610 1620 1630 1640 1650
    PEEELRTCFV IQGSMTQESV LDFTRFSKWR RLLGAMAYIH RFLDNCRRKC
    1660 1670 1680 1690 1700
    RNEKLELQYL SQDELQKAKN TLMRIVQWQE YPEEMALFLK GSVELPRTSS
    1710 1720 1730 1740 1750
    LYQLTPAVDE YGVLRVDGRI GAAPHVAFDA RFPVILPRRH PVTKLVVEDF
    1760 1770 1780 1790 1800
    HRTFRHGNSE TVVNEIRQFF HIFRLRTVVK QVTAACQWCK VMKATPKVPR
    1810 1820 1830 1840 1850
    MAPLPVARLS SFARPFTYTG IDFFGPLLVK VGRSAAKRWI CLFTCLTTRA
    1860 1870 1880 1890 1900
    VHVEVAYSLS TQSCVKCVRR FVCRRGAPAE IYTDNGTNFL GAECILREQI
    1910 1920 1930 1940 1950
    RALHSDLSAT FTNTDTKWIF IPPGAPHMGG AWERMVRSVK SAMESAYNSD
    1960 1970 1980 1990 2000
    RKLDDVGLET LVVEAEGIVN SRPLTYLPLD AAEGESLTPN HFLLGSSRGV
    2010 2020 2030 2040 2050
    RQPAVPCSDP ATAIKNSWTL IQHQLDVFWK RWVREYLPML TRRMKWFGEI
    2060 2070 2080 2090 2100
    APVAAGDLVL IVDDTRRNGW TRGRVKEVLT AEDGRVRQAV VQTARGLLRR
    2110 2120 2130
    PVAKLAVLEV ESGGKTGTGG QCYGGEDVAA STVPQCDRT
    Length:2,139
    Mass (Da):239,422
    Last modified:September 7, 2016 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1EF671F5ED5A1F88
    GO

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    JXUM01136032 Genomic DNA No translation available.
    KQ568367 Genomic DNA Translation: KXJ69026.1

    Genome annotation databases

    Ensembl metazoan genome annotation project

    More...
    EnsemblMetazoai
    AALF000451-RA; AALF000451-PA; AALF000451

    Bioinformatics Resource for Invertebrate Vectors of Human Pathogens

    More...
    VectorBasei
    AALF000451-RA; AALF000451-PA; AALF000451

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    JXUM01136032 Genomic DNA No translation available.
    KQ568367 Genomic DNA Translation: KXJ69026.1

    3D structure databases

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    SWISS-MODEL Interactive Workspace

    More...
    SWISS-MODEL-Workspacei
    Submit a new modelling project...

    Genome annotation databases

    EnsemblMetazoaiAALF000451-RA; AALF000451-PA; AALF000451
    VectorBaseiAALF000451-RA; AALF000451-PA; AALF000451

    Family and domain databases

    Gene3Di3.30.40.10, 1 hit
    3.30.420.10, 1 hit
    3.30.70.270, 1 hit
    InterProiView protein in InterPro
    IPR043502, DNA/RNA_pol_sf
    IPR005312, DUF1759
    IPR040676, DUF5641
    IPR001584, Integrase_cat-core
    IPR008042, Retrotrans_Pao
    IPR043128, Rev_trsase/Diguanyl_cyclase
    IPR012337, RNaseH-like_sf
    IPR036397, RNaseH_sf
    IPR019786, Zinc_finger_PHD-type_CS
    IPR011011, Znf_FYVE_PHD
    IPR001965, Znf_PHD
    IPR019787, Znf_PHD-finger
    IPR013083, Znf_RING/FYVE/PHD
    PfamiView protein in Pfam
    PF03564, DUF1759, 1 hit
    PF18701, DUF5641, 1 hit
    PF05380, Peptidase_A17, 1 hit
    SMARTiView protein in SMART
    SM00249, PHD, 1 hit
    SUPFAMiSSF53098, SSF53098, 1 hit
    SSF56672, SSF56672, 1 hit
    SSF57903, SSF57903, 1 hit
    PROSITEiView protein in PROSITE
    PS50994, INTEGRASE, 1 hit
    PS01359, ZF_PHD_1, 1 hit
    PS50016, ZF_PHD_2, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A182G158_AEDAL
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A182G158
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 7, 2016
    Last sequence update: September 7, 2016
    Last modified: October 7, 2020
    This is version 23 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteomeImported
    UniProt is an ELIXIR core data resource
    Main funding by: National Institutes of Health

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