Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Pseudomonas putida (Arthrobacter siderocapsulatus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotationSAAS annotation

Pathwayi: NAD(+) biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Nicotinate phosphoribosyltransferase, Nicotinate phosphoribosyltransferase (pncB2), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB2), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB2), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB), Nicotinate phosphoribosyltransferase (pncB)
This subpathway is part of the pathway NAD(+) biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate, the pathway NAD(+) biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseImported, LigaseUniRule annotationSAAS annotation, Transferase
Biological processPyridine nucleotide biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayi
UPA00253;UER00457

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotationSAAS annotation (EC:6.3.4.21UniRule annotationSAAS annotation)
Short name:
NAPRTaseUniRule annotation
Gene namesi
Name:pncBUniRule annotation
ORF Names:AYO08_12645Imported
OrganismiPseudomonas putida (Arthrobacter siderocapsulatus)Imported
Taxonomic identifieri303 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000078222 Componenti: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliA0A179RE60
SMRiA0A179RE60
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd01401 PncB_like, 1 hit
HAMAPiMF_00570 NAPRTase, 1 hit
InterProiView protein in InterPro
IPR006406 Nic_PRibTrfase
IPR007229 Nic_PRibTrfase-Fam
IPR036068 Nicotinate_pribotase_like_C
PANTHERiPTHR11098 PTHR11098, 1 hit
PfamiView protein in Pfam
PF04095 NAPRTase, 1 hit
PIRSFiPIRSF000484 NAPRT, 1 hit
SUPFAMiSSF51690 SSF51690, 1 hit
TIGRFAMsiTIGR01514 NAPRTase, 1 hit

Sequencei

Sequence statusi: Complete.

A0A179RE60-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSESAFAERI VHNLLDTDFY KLTMMQGVLH NYPDADVEWE FRCRNGEDLR
60 70 80 90 100
PYLGEIRNQL ERLADLTLDD GQLAFLERIS FLKPDFLRFL RLFRFNLRYV
110 120 130 140 150
HVGIENDQLF LRLKGPWLHV ILFEVPLLAI ISEVRNRNLH PHMRLAEARD
160 170 180 190 200
QLYRKFDWLR AHASDDELAE LQVADFGTRR RFSSRVQEEV ARVLRDDFPG
210 220 230 240 250
RFVGTSNVDL AWKLDIKPLG TMAHEWIMAH QQLGPRLIDS QIAALDCWVR
260 270 280 290 300
EYRGLLGIAL TDCITMDAFL GDFDLYFAKL FDGLRHDSGE PVAWAEKAIA
310 320 330 340 350
HYQKLGIDPM TKTLVFSDGL NLTRSLEIFR ALRGRINVSF GIGTNLTCDI
360 370 380 390 400
PGVAPMNIVL KMTDCNGAPV AKISDEAAKT QCRDENFVAY MRHVFKVPSK

E
Length:401
Mass (Da):46,218
Last modified:September 7, 2016 - v1
Checksum:iAD30738BE61C3089
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LSUZ01000183 Genomic DNA Translation: OAS06144.1
RefSeqiWP_049586710.1, NZ_LT799039.1

Genome annotation databases

EnsemblBacteriaiOAS06144; OAS06144; AYO08_12645
PATRICifig|303.175.peg.3724

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LSUZ01000183 Genomic DNA Translation: OAS06144.1
RefSeqiWP_049586710.1, NZ_LT799039.1

3D structure databases

ProteinModelPortaliA0A179RE60
SMRiA0A179RE60
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiOAS06144; OAS06144; AYO08_12645
PATRICifig|303.175.peg.3724

Enzyme and pathway databases

UniPathwayi
UPA00253;UER00457

Family and domain databases

CDDicd01401 PncB_like, 1 hit
HAMAPiMF_00570 NAPRTase, 1 hit
InterProiView protein in InterPro
IPR006406 Nic_PRibTrfase
IPR007229 Nic_PRibTrfase-Fam
IPR036068 Nicotinate_pribotase_like_C
PANTHERiPTHR11098 PTHR11098, 1 hit
PfamiView protein in Pfam
PF04095 NAPRTase, 1 hit
PIRSFiPIRSF000484 NAPRT, 1 hit
SUPFAMiSSF51690 SSF51690, 1 hit
TIGRFAMsiTIGR01514 NAPRTase, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A179RE60_PSEPU
AccessioniPrimary (citable) accession number: A0A179RE60
Entry historyiIntegrated into UniProtKB/TrEMBL: September 7, 2016
Last sequence update: September 7, 2016
Last modified: April 25, 2018
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again