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Protein

Pyruvate kinase

Gene

AXX17_At3g24740

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + pyruvate = ADP + phosphoenolpyruvate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 5 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic (GAPC1), Glyceraldehyde-3-phosphate dehydrogenase GAPC2, cytosolic (GAPC2)
  2. Phosphoglycerate kinase 3, cytosolic (PGK3)
  3. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1 (PGM1), Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2 (At3g08590)
  4. Cytosolic enolase 3 (ENO3), Enolase 1, chloroplastic (ENO1), Bifunctional enolase 2/transcriptional activator (ENO2)
  5. Probable pyruvate kinase, cytosolic isozyme (At4g26390), Plastidial pyruvate kinase 1, chloroplastic (PKP1), Plastidial pyruvate kinase 3, chloroplastic (PKP3), Plastidial pyruvate kinase 2 (PKP2), Plastidial pyruvate kinase 4, chloroplastic (PKP4), Pyruvate kinase (F1I16_60), Pyruvate kinase (At3g25960), Pyruvate kinase (At3g04050), Pyruvate kinase (MBK5.16), Pyruvate kinase (At3g52990), Pyruvate kinase (At2g36580), Pyruvate kinase (F1I16_220), Pyruvate kinase (At3g52990), Pyruvate kinase (MAH20.13), Pyruvate kinase (MCD7.8), Pyruvate kinase, Pyruvate kinase (AXX17_At1g33230), Pyruvate kinase (AXX17_At2g33300), Pyruvate kinase (AXX17_At3g50440), Pyruvate kinase (AXX17_At4g30430), Pyruvate kinase (AXX17_At5g51800), Pyruvate kinase (AXX17_At3g28070), Pyruvate kinase, Pyruvate kinase (AXX17_At3g47400), Pyruvate kinase (F8J2_160), Pyruvate kinase (AXX17_At3g03460), Pyruvate kinase (AXX17_ATUG04870), Pyruvate kinase (AXX17_At3g24740), Pyruvate kinase (AXX17_At3g50280), Pyruvate kinase (AXX17_At5g55530), Pyruvate kinase (At5g63680)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotation, Transferase
Biological processGlycolysisUniRule annotation
LigandMagnesiumUniRule annotation

Enzyme and pathway databases

UniPathwayi
UPA00109;UER00188

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate kinaseUniRule annotation (EC:2.7.1.40UniRule annotation)
Gene namesi
Ordered Locus Names:AXX17_At3g24740Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000078284 Componenti: Chromosome 3

Expressioni

Gene expression databases

ExpressionAtlasiA0A178VM70 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini117 – 462PKInterPro annotationAdd BLAST346
Domaini487 – 586PK_CInterPro annotationAdd BLAST100

Sequence similaritiesi

Belongs to the pyruvate kinase family.UniRule annotation

Family and domain databases

Gene3Di2.40.33.10, 1 hit
3.40.1380.20, 1 hit
InterProiView protein in InterPro
IPR001697 Pyr_Knase
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
IPR011037 Pyrv_Knase-like_insert_dom_sf
IPR018209 Pyrv_Knase_AS
IPR015793 Pyrv_Knase_brl
IPR015795 Pyrv_Knase_C
IPR036918 Pyrv_Knase_C_sf
IPR015806 Pyrv_Knase_insert_dom_sf
PANTHERiPTHR11817 PTHR11817, 1 hit
PfamiView protein in Pfam
PF00224 PK, 1 hit
PF02887 PK_C, 1 hit
PRINTSiPR01050 PYRUVTKNASE
SUPFAMiSSF50800 SSF50800, 1 hit
SSF51621 SSF51621, 2 hits
SSF52935 SSF52935, 1 hit
TIGRFAMsiTIGR01064 pyruv_kin, 1 hit
PROSITEiView protein in PROSITE
PS00110 PYRUVATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A178VM70-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQSIQFSSP SHTPHLLHLP HSQFNRPLSS ISFRRFPLTT IKYTSIRASS
60 70 80 90 100
SPSPSPDLDS SSSSSSSQVL LSPNGTGAVK SDERSVVATA VTTDTSGIEV
110 120 130 140 150
DTVTEAELKE NGFRSTRRTK LICTIGPATC GFEQLEALAV GGMNVARLNM
160 170 180 190 200
CHGTRDWHRG VIRSVRRLNE EKGFAVAIMM DTEGSEIHMG DLGGEASAKA
210 220 230 240 250
EDGEVWTFTV RAFDSSRPER TISVSYDGFA EDVRVGDELL VDGGMVRFEV
260 270 280 290 300
IEKIGPDVKC LCTDPGLLLP RANLTFWRDG SLVRERNAML PTISSKDWLD
310 320 330 340 350
IDFGIAEGVD FIAVSFVKSA EVINHLKSYL AARSRGGEIG VIAKIESIDS
360 370 380 390 400
LTNLEEIILA SDGAMVARGD LGAQIPLEQV PAAQQRIVQV CRALNKPVIV
410 420 430 440 450
ASQLLESMIE YPTPTRAEVA DVSEAVRQRS DALMLSGESA MGQFPDKALT
460 470 480 490 500
VLRTVSLRIE RWWREEKRHE SVPLQAIGSS FSDKISEEIC NSAAKMANNL
510 520 530 540 550
GVDAVFVYTT SGHMASLVSR CRPDCPIFAF TTTTSVRRRL NLQWGLIPFR
560 570 580 590
LSFSDDMESN LNKTFSLLKS RGMIKSGDLV IAVSDMLQSI QVMNVP
Length:596
Mass (Da):65,127
Last modified:September 7, 2016 - v1
Checksum:iBF21ED968FB8FFBB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LUHQ01000003 Genomic DNA Translation: OAP05902.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LUHQ01000003 Genomic DNA Translation: OAP05902.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayi
UPA00109;UER00188

Gene expression databases

ExpressionAtlasiA0A178VM70 baseline and differential

Family and domain databases

Gene3Di2.40.33.10, 1 hit
3.40.1380.20, 1 hit
InterProiView protein in InterPro
IPR001697 Pyr_Knase
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
IPR011037 Pyrv_Knase-like_insert_dom_sf
IPR018209 Pyrv_Knase_AS
IPR015793 Pyrv_Knase_brl
IPR015795 Pyrv_Knase_C
IPR036918 Pyrv_Knase_C_sf
IPR015806 Pyrv_Knase_insert_dom_sf
PANTHERiPTHR11817 PTHR11817, 1 hit
PfamiView protein in Pfam
PF00224 PK, 1 hit
PF02887 PK_C, 1 hit
PRINTSiPR01050 PYRUVTKNASE
SUPFAMiSSF50800 SSF50800, 1 hit
SSF51621 SSF51621, 2 hits
SSF52935 SSF52935, 1 hit
TIGRFAMsiTIGR01064 pyruv_kin, 1 hit
PROSITEiView protein in PROSITE
PS00110 PYRUVATE_KINASE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A178VM70_ARATH
AccessioniPrimary (citable) accession number: A0A178VM70
Entry historyiIntegrated into UniProtKB/TrEMBL: September 7, 2016
Last sequence update: September 7, 2016
Last modified: February 28, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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