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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Thermococcus piezophilus
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotation, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
ORF Names:A7C91_08565Imported
OrganismiThermococcus piezophilusImported
Taxonomic identifieri1712654 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
Proteomesi
  • UP000076969 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 95Arg_tRNA_synt_NInterPro annotationAdd BLAST84
Domaini520 – 642DALR_1InterPro annotationAdd BLAST123

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili184 – 204Sequence analysisAdd BLAST21
Coiled coili233 – 253Sequence analysisAdd BLAST21
Coiled coili455 – 475Sequence analysisAdd BLAST21

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi133 – 143"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

KOiK01887

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 2 hits
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A0A172WIW4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGYTEVKEKA KLILMEELEK MLKESGKEWE GETTFDETPS VEFGDFATTV
60 70 80 90 100
SFQLARVFRK APKLIAEEIV KRIDRKLPEE IAKVEAVNGY VNFFLDYERF
110 120 130 140 150
GRNLINEILS MGERYGESKL GKGKKVIVEH TSVNPTKPLH MGHARNAVLG
160 170 180 190 200
DTMARIMRAI GYNVEVQNYI DDLGVQFAQV LWGYLNLKEE FERLEAELRE
210 220 230 240 250
KGVKEDVIDH VMGLLYVEVN NRIEGNPEVD KEVRELMKKL EEGDNEIAKI
260 270 280 290 300
GRKLAERVVK AQMMTTYRMN IIYDLLSWES DIMRSGIFEE AYSLIESNPN
310 320 330 340 350
FFWAKKGKYK GAFVMDLRKL FPDMKNPFLV LKRSDGTATY TGKDIAYHLW
360 370 380 390 400
KFGKVSSDML YKPWDRLEDH RTWTTASDGE KMPGKFGKAD IVINVIGIEQ
410 420 430 440 450
KHPQMAIKYA LRLLGFEDSA ENFHHLAYEH VVRPEGKFSG RKGTWVGFTV
460 470 480 490 500
DEVLNEAVKR AKELVEEKNP NLSEEEKEKI AEAVGVGAVR FNLIKYSPDK
510 520 530 540 550
IITFRWEDVL NFEGESAPYV QYAHARCASI LRKAESSGIS TDWKDLIEKA
560 570 580 590 600
DFSKLTRREK ELIKLLAKFP EIVEQAGRDI KPHLIPWFAN ELASLFNRFY
610 620 630 640
MDHPVLKAED GVREERLLLV LATKGVLRNA LALLGIEAPE KM
Length:642
Mass (Da):73,772
Last modified:September 7, 2016 - v1
Checksum:iAC1B698A53B458CD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP015520 Genomic DNA Translation: ANF23215.1
RefSeqiWP_068666652.1, NZ_CP015520.1

Genome annotation databases

EnsemblBacteriaiANF23215; ANF23215; A7C91_08565
GeneIDi28496241
KEGGitpie:A7C91_08565

Similar proteinsi

Entry informationi

Entry nameiA0A172WIW4_9EURY
AccessioniPrimary (citable) accession number: A0A172WIW4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 7, 2016
Last sequence update: September 7, 2016
Last modified: June 20, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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