UniProtKB - A0A172Q385 (A0A172Q385_HUMAN)
Protein
Submitted name:
Tumor endothelial marker 5
Gene
TEM5
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Tumor endothelial marker 5Imported |
Gene namesi | Name:TEM5Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
MembranePTM / Processingi
Keywords - PTMi
Disulfide bondARBA annotationProteomic databases
PeptideAtlasi | A0A172Q385 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 226 – 310 | Ig-likeInterPro annotationAdd BLAST | 85 | |
Domaini | 293 – 387 | G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST | 95 | |
Domaini | 673 – 724 | GPSInterPro annotationAdd BLAST | 52 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 531 – 557 | DisorderedSequence analysisAdd BLAST | 27 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 540 – 554 | Pro-richSequence analysisAdd BLAST | 15 |
Keywords - Domaini
Leucine-rich repeatARBA annotation, RepeatARBA annotation, SignalARBA annotation, Transmembrane, Transmembrane helixARBA annotationFamily and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.80.10.10, 2 hits 4.10.1240.10, 1 hit |
InterProi | View protein in InterPro IPR000483, Cys-rich_flank_reg_C IPR036445, GPCR_2_extracell_dom_sf IPR001879, GPCR_2_extracellular_dom IPR000203, GPS IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf |
Pfami | View protein in Pfam PF01825, GPS, 1 hit PF13855, LRR_8, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 1 hit SM00369, LRR_TYP, 4 hits SM00082, LRRCT, 1 hit |
SUPFAMi | SSF111418, SSF111418, 1 hit SSF48726, SSF48726, 1 hit |
PROSITEi | View protein in PROSITE PS50227, G_PROTEIN_RECEP_F2_3, 1 hit PS50221, GPS, 1 hit PS50835, IG_LIKE, 1 hit PS51450, LRR, 4 hits |
i Sequence
Sequence statusi: Fragment.
A0A172Q385-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
PGCPLSIRSC KCSGERPKGL SGGVPGPARR RVVCSGGDLP EPPEPGLLPN
60 70 80 90 100
GTVTLLLSNN KITGLRNGSF LGLSLLEKLD LRNNIISTVQ PGAFLGLGEL
110 120 130 140 150
KRLDLSNNRI GCLTSETFQG LPRLLRLNIS GNIFSSLQPG VFDELPALKV
160 170 180 190 200
VDLGTEFLTC DCHLRWLLPW AQNRSLQLSE HTLCAYPSAL HAQALGSLQE
210 220 230 240 250
AQLCCEGALE LHTHHLIPSL RQVVFQGDRL PFQCSASYLG NDTRIRWYHN
260 270 280 290 300
RAPVEGDEQA GILLAESLIH DCTFITSELT LSHIGVWASG EWECTVSMAQ
310 320 330 340 350
GNASKKVEIV VLETSASYCP AERVANNRGD FRWPRTLAGI TAYQSCLQYP
360 370 380 390 400
FTSVPLGGGA PGTRASRRCD RAGRWEPGDY SHCLYTNDIT RVLYTFVLMP
410 420 430 440 450
INASNALTLA HQLRVYTAEA ASFSDMMDVV YVAQMIQKFL GYVDQIKELV
460 470 480 490 500
EVMVDMASNL MLVDEHLLWL AQREDKACSR IVGALERIGG AALSPHAQHI
510 520 530 540 550
SVNARNVALE AYLIKPHSYV GLTCTAFQRR EGGVPGTRPG SPGQNPPPEP
560 570 580 590 600
EPPADQQLRF RCTTGRPNVS LSSFHIKNSV ALASIQLPPS LFSSLPAALA
610 620 630 640 650
PPVPPDCTLQ LLVFRNGRLF HSHSNTSRPG AAGPGKRRGV ATPVIFAGTS
660 670 680 690 700
GCGVGNLTEP VAVSLRHWAE GAEPVAAWWS QEGPGEAGGW TSEGCQLRSS
710 720 730
QPNVSALHCQ HLGNVAVLME LSAFPREVGG AGAGLH
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 736 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | KU257672 mRNA Translation: AND76657.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | KU257672 mRNA Translation: AND76657.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | A0A172Q385 |
Miscellaneous databases
ChiTaRSi | ADGRA2, human |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.80.10.10, 2 hits 4.10.1240.10, 1 hit |
InterProi | View protein in InterPro IPR000483, Cys-rich_flank_reg_C IPR036445, GPCR_2_extracell_dom_sf IPR001879, GPCR_2_extracellular_dom IPR000203, GPS IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf |
Pfami | View protein in Pfam PF01825, GPS, 1 hit PF13855, LRR_8, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 1 hit SM00369, LRR_TYP, 4 hits SM00082, LRRCT, 1 hit |
SUPFAMi | SSF111418, SSF111418, 1 hit SSF48726, SSF48726, 1 hit |
PROSITEi | View protein in PROSITE PS50227, G_PROTEIN_RECEP_F2_3, 1 hit PS50221, GPS, 1 hit PS50835, IG_LIKE, 1 hit PS51450, LRR, 4 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A172Q385_HUMAN | |
Accessioni | A0A172Q385Primary (citable) accession number: A0A172Q385 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 7, 2016 |
Last sequence update: | September 7, 2016 | |
Last modified: | October 7, 2020 | |
This is version 18 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |