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Protein

Membrane protein insertase YidC

Gene

yidC

Organism
Leptospira interrogans serovar Pomona
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

GO - Molecular functioni

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation
Biological processProtein transportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Membrane protein insertase YidCUniRule annotationSAAS annotation
Alternative name(s):
Foldase YidCUniRule annotation
Membrane integrase YidCUniRule annotation
Membrane protein YidCUniRule annotation
Gene namesi
Name:yidCUniRule annotation
ORF Names:BW243_00875Imported
OrganismiLeptospira interrogans serovar PomonaImported
Taxonomic identifieri44276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira
Proteomesi
  • UP000186965 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 27HelicalUniRule annotationAdd BLAST21
Transmembranei425 – 444HelicalUniRule annotationAdd BLAST20
Transmembranei488 – 511HelicalUniRule annotationAdd BLAST24
Transmembranei539 – 558HelicalUniRule annotationAdd BLAST20
Transmembranei579 – 604HelicalUniRule annotationAdd BLAST26

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Interactioni

Subunit structurei

Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_01810 YidC_type1, 1 hit
InterProiView protein in InterPro
IPR019998 Membr_insert_YidC
IPR028055 Membr_insert_YidC/Oxa1_C
IPR001708 YidC/ALB3/OXA1/COX18
PANTHERiPTHR12428 PTHR12428, 1 hit
PfamiView protein in Pfam
PF02096 60KD_IMP, 1 hit
TIGRFAMsiTIGR03592 yidC_oxa1_cterm, 1 hit

Sequencei

Sequence statusi: Complete.

A0A163NRG8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDRQTRLFL ALILSMGIWM GVNYFFFPNT SIKKNTETKQ TQSDKTSENT
60 70 80 90 100
KQQITSGKTK ESNSADPVVQ KEKITPFDTK KSFIVTDSYI VEFSSLGGKI
110 120 130 140 150
SKFYMKDFTG PNGELIQVAR KNPETVAVDG KSYQAVELSR EKGFDFNFSD
160 170 180 190 200
SLNELPDSEW NQISFSLEEN KTDGSSAYIR FIALSLDKTY QLTKTFLFFK
210 220 230 240 250
SENYFKVTFS ITNLTKEKLS FASQKNVRYL RTFGSLGPYP KDRPLSDRDT
260 270 280 290 300
ANFFRFYYLG GSFQDTLDGS SSVGFWSSVG NFFTGNSGTD ESFSIKTDKE
310 320 330 340 350
SGVDFAGTGS RYFIAVADPL DHKPHGIVLD NRPKNESGAV LVYDNILLNP
360 370 380 390 400
GENYNLDFAS YVGIRESEGM AFKNPELDPS QSKNSPFVGL SSDLNKSFNQ
410 420 430 440 450
GITTPFRNGI IWILKQIYRF TIPNYGWSII IFAILFKLVF YPLNQKQADS
460 470 480 490 500
MKKMQELSPQ LKTINEKFAN DPKMRQQKTM ELYKKNNVNP VGGCLPMVIQ
510 520 530 540 550
IPIFIALYTA FSDTIDLWNS PFLWVKDLSE PDVIWTSPAI PYFTQTGIGL
560 570 580 590 600
NLLALLMVGT QVFQTRMTSV SMDPNQKMLM YVMPVMMLYI FWNMPSGVTL
610 620 630
YWTFQNVLSI GQQWITNHLK KTEEKKKAKV
Length:630
Mass (Da):71,708
Last modified:July 6, 2016 - v1
Checksum:i41E7A25AA7AE2427
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MTJU01000005 Genomic DNA Translation: OMH73302.1
RefSeqiWP_000390184.1, NZ_MTJU01000005.1

Similar proteinsi

Entry informationi

Entry nameiA0A163NRG8_LEPIR
AccessioniPrimary (citable) accession number: A0A163NRG8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 6, 2016
Last sequence update: July 6, 2016
Last modified: May 23, 2018
This is version 12 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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