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Protein

Ribosomal protein S6 kinase

Gene
N/A
Organism
Fundulus heteroclitus (Killifish) (Mummichog)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei98ATPUniRule annotation1
Active sitei193Proton acceptorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi72 – 80ATPUniRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal protein S6 kinaseUniRule annotation (EC:2.7.11.1UniRule annotation)
OrganismiFundulus heteroclitus (Killifish) (Mummichog)Imported
Taxonomic identifieri8078 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesFundulidaeFundulus

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 327Protein kinaseInterPro annotationAdd BLAST262
Domaini328 – 398AGC-kinase C-terminalInterPro annotationAdd BLAST71

Sequence similaritiesi

Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.UniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR000961 AGC-kinase_C
IPR011009 Kinase-like_dom_sf
IPR017892 Pkinase_C
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR016238 Ribosomal_S6_kinase
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
PF00433 Pkinase_C, 1 hit
PIRSFiPIRSF000605 Ribsml_S6_kin_1, 1 hit
SMARTiView protein in SMART
SM00133 S_TK_X, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

A0A146QYB7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGVFDIDLD QPDDNVSDDD LEDGAQHGEY MDQCSSFDFN MDGCEKFEIS
60 70 80 90 100
ENSVNKGTEQ IGPECFELLK VLGKGGYGKV FQVRKVIGAA SGKIFAMKVL
110 120 130 140 150
KKAMIVRNAK DTAHTKAERN ILEEVKHPFI VDLIYAFQTG GKLYLILEYL
160 170 180 190 200
SGGELFMQLE REGIFMEDTA CFYLAEISMA LGHLHQKGII YRDLKPENIM
210 220 230 240 250
LNNNGHVKLT DFGLCKESIH DGTYTHTFCG TIEYMAPEIL MRSGHNRAVD
260 270 280 290 300
WWSLGALMYD MLTGAPPFTG ENRKKTIDKI LKCKLSLPPY LTQEARDLLK
310 320 330 340 350
KLLRRSASSR LGGGSGDSAE VQAHPFFRFI NWDDLLARKV EPPFKPFLQS
360 370 380 390 400
ADDVSQFDSK FTSQTPVDSP DDSTLSESAN QVFLGFTYVA PSVLENLKEK
410 420 430 440 450
FSFEPKIRSP RKFPGSPRTP VSPVKFAGGD CWPRGPPLTD TPPLLSPSSS
460 470 480 490 500
IDQPMEVSAM EQMDTSSGFT TETSAPLPIR HPSGLHAGPY KKQAYPINSR

RPEHLRMNL
Length:509
Mass (Da):56,791
Last modified:June 8, 2016 - v1
Checksum:i47347B3FDDCD20E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GCES01125077 Transcribed RNA Translation: JAQ61245.1

Similar proteinsi

Entry informationi

Entry nameiA0A146QYB7_FUNHE
AccessioniPrimary (citable) accession number: A0A146QYB7
Entry historyiIntegrated into UniProtKB/TrEMBL: June 8, 2016
Last sequence update: June 8, 2016
Last modified: February 28, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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