The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - A0A144A140 (A0A144A140_PLAF7)
Protein
Submitted name:
Tryptophan--tRNA ligase
Gene
PF3D7_1251700
Organism
Plasmodium falciparum (isolate 3D7)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- tryptophan-tRNA ligase activity Source: GO_Central
GO - Biological processi
- tryptophanyl-tRNA aminoacylation Source: GO_Central
Keywordsi
Molecular function | Aminoacyl-tRNA synthetaseUniRule annotationARBA annotation, Ligase |
Biological process | Protein biosynthesisUniRule annotationARBA annotation |
Ligand | ATP-bindingUniRule annotationARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | ORF Names:PF3D7_1251700Imported |
Organismi | Plasmodium falciparum (isolate 3D7)Imported |
Taxonomic identifieri | 36329 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodiidae › Plasmodium › Plasmodium (Laverania) › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | PlasmoDB:PF3D7_1251700 |
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 6 – 23 | HelicalSequence analysisAdd BLAST | 18 |
Keywords - Cellular componenti
MembraneStructurei
3D structure databases
AlphaFoldDBi | A0A144A140 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Sequence similaritiesi
Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
PhylomeDBi | A0A144A140 |
Family and domain databases
Gene3Di | 3.40.50.620, 2 hits |
InterProi | View protein in InterPro IPR001412, aa-tRNA-synth_I_CS IPR002305, aa-tRNA-synth_Ic IPR014729, Rossmann-like_a/b/a_fold |
Pfami | View protein in Pfam PF00579, tRNA-synt_1b, 1 hit |
PROSITEi | View protein in PROSITE PS00178, AA_TRNA_LIGASE_I, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A144A140-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIKGNIYLLT YFLIINFILC TNIQSISRKT KNVPLLPFFF TLPYTKRIKR
60 70 80 90 100
SDLQSKRDCT FFTGIKPSGN IHLGNYIGCL HPIINVEATK KCSNNLSNKN
110 120 130 140 150
ESVIKLNKII LIADLHCLTK LSNIYSLKDK VIDSVKIIIS LIIDMYKKKQ
160 170 180 190 200
SYVDVYINNV KLEDILQLIE NKEPNKSNHN NENNNNNNLY EQIASHTSQF
210 220 230 240 250
HNHIKTDNLG GDMNCVEFPS QECHNHKNKP IKQKHYFYIF KQSDIKLHTS
260 270 280 290 300
LYYLINSFTS INMLNSHIHI KMGGHNKSVA LFSYPSLMLA DILLYKPTYL
310 320 330 340 350
IIGQDQIKNM EIMKKLCRKI NYHFSNVAKL PKIFFSKFYS EVMNLDGHKK
360 370 380 390 400
MSKNHLLHHD KDTSKIIYLL DNKKTIENKI KKSKTDNYNI LIYGQEDRKE
410 420 430 440 450
INNLINIFFF FYYHQIKNKK YINRTCNNNE NDNNENQNIS KLSYIYDEHQ
460 470 480 490 500
LFINNQRTHN YLNDFTNNPN FSHYKQNNIN PHFNQNIINK ILHSYNNNYS
510 520 530 540 550
KFKYDLSQLI YNHFITTKIY YNSFNTRHDL IHSILQNGKK CVHRRASQMY
KVIKKKLNI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | LN999947 Genomic DNA Translation: CZT99672.1 |
Genome annotation databases
EnsemblProtistsi | CZT99672; CZT99672; PF3D7_1251700 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | LN999947 Genomic DNA Translation: CZT99672.1 |
3D structure databases
AlphaFoldDBi | A0A144A140 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 5833.PFL2485c |
Chemistry databases
GuidetoPHARMACOLOGYi | 3166 |
Genome annotation databases
EnsemblProtistsi | CZT99672; CZT99672; PF3D7_1251700 |
Organism-specific databases
VEuPathDBi | PlasmoDB:PF3D7_1251700 |
Phylogenomic databases
PhylomeDBi | A0A144A140 |
Family and domain databases
Gene3Di | 3.40.50.620, 2 hits |
InterProi | View protein in InterPro IPR001412, aa-tRNA-synth_I_CS IPR002305, aa-tRNA-synth_Ic IPR014729, Rossmann-like_a/b/a_fold |
Pfami | View protein in Pfam PF00579, tRNA-synt_1b, 1 hit |
PROSITEi | View protein in PROSITE PS00178, AA_TRNA_LIGASE_I, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A144A140_PLAF7 | |
Accessioni | A0A144A140Primary (citable) accession number: A0A144A140 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 8, 2016 |
Last sequence update: | June 8, 2016 | |
Last modified: | May 25, 2022 | |
This is version 20 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |