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Protein
Submitted name:

Non-SERCA-type Ca2+-transporting P-ATPase

Gene

PF3D7_1211900

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseSAAS annotationImported
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Non-SERCA-type Ca2+-transporting P-ATPaseImported (EC:3.6.3.8Imported)
Gene namesi
ORF Names:PF3D7_1211900Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 12

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei165 – 191HelicalSequence analysisAdd BLAST27
Transmembranei197 – 214HelicalSequence analysisAdd BLAST18
Transmembranei357 – 381HelicalSequence analysisAdd BLAST25
Transmembranei393 – 419HelicalSequence analysisAdd BLAST27
Transmembranei923 – 944HelicalSequence analysisAdd BLAST22
Transmembranei996 – 1023HelicalSequence analysisAdd BLAST28
Transmembranei1201 – 1223HelicalSequence analysisAdd BLAST23
Transmembranei1229 – 1250HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

DrugBankiDB11638 Artenimol

Structurei

3D structure databases

ProteinModelPortaliA0A143ZZK9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini118 – 193Cation_ATPase_NInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. [View classification]SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR006068 ATPase_P-typ_cation-transptr_C
IPR004014 ATPase_P-typ_cation-transptr_N
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00689 Cation_ATPase_C, 1 hit
PF00690 Cation_ATPase_N, 1 hit
PRINTSiPR00120 HATPASE
SMARTiView protein in SMART
SM00831 Cation_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 2 hits
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 4 hits
TIGRFAMsiTIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A143ZZK9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSQNNNKQG GQDINNKKDS DDIKPSVSKE DLINSLKNDE LNKNTTMDQN
60 70 80 90 100
DMKKNENMNI KKNEVLNNSN NVEDGDNENS KFMNKSKEGL NNINGEKNDD
110 120 130 140 150
NNSIVKVEES PKSIGYNYYA SESIENLCKE FGLESINTGL NSEQVKINRD
160 170 180 190 200
KYGENFIEKD EVVPVWLIFL SQYCSPVVLL LLVAAVASLA LNEVVEGVAI
210 220 230 240 250
ISIVTLNACL ATYMEKSSGD AIGKLAEMAS PQCTVLRNGQ KVVIPSREVV
260 270 280 290 300
VGDVVLINTG DSISADLRLF DVIELKTNES LLTGESEDIK KTIVADNLST
310 320 330 340 350
PFATNLCFAT TSVTSGSGKG IVISTGLDTQ VGKIASQLKK SSKGSKLTPL
360 370 380 390 400
QVALNKLGGL IGLIAIIVLV VIISLAVIIK YRDPAHADKD PTFVIIIIGV
410 420 430 440 450
GFAVSSIPEG LPMVVTITLS AGAKDMVKKN ANVRKLPAVE TLGCCSVICS
460 470 480 490 500
DKTGTLTEGK MTAINAVTIC KNSSLSDENN KLTKTFDFYP TKGFEPCGGL
510 520 530 540 550
FDSNELTSEK KKEIVIAKNQ NTSYDKVLYN YGNPSNKSVI VDKTRSLMFA
560 570 580 590 600
AYLNSYDTTL SRDPKTLKWG IHGNMSEGPI VVAAAKVGYS FINNPNHKSY
610 620 630 640 650
LDNFQRLDDL EVTFNSSRKM KITFYKLKTV NVFENVYLDK PGKVYTHVAL
660 670 680 690 700
IKGAPDRLLD RSTHLLEETS MKKVQVSWNS TITQEERNVL IKKNLELSQK
710 720 730 740 750
ALRVLSICIK PLTDQNIEEL KKLEDADERL KYVNYDENGG FIPMGYVASF
760 770 780 790 800
DPPRPGVKEA IQTCREAQVK VIMITGDQKP TAVAIGKLIG LIEEKSEQVE
810 820 830 840 850
DINSLAIECS ELHINKNPNE PILPNDQLDE FTDKILIYSR AQPEDKITIV
860 870 880 890 900
QSLKRKGYLV AMTGDGVNDA PALKAADIGV AMGINGTEVA KGASEMILID
910 920 930 940 950
DNFCTVVSAI DVGRTIFSNI QKFVCFLLGT NIGEIIYLSV AIVAQMPFPL
960 970 980 990 1000
EALQILFLNL MTDGCPAVAL SREPPNDDNM KTPPRPKKQP IMTKRWWFYG
1010 1020 1030 1040 1050
ILPHTIFEAL CVLLSLAFSL YICTGFYNLN GIHNLCKTVN LVDVNDANVY
1060 1070 1080 1090 1100
HEYKYFCSSY EYRISTDYVG WVTNVSFWDP QNNEAVNFWG AAKGKVENIN
1110 1120 1130 1140 1150
PLSDIVHPEL RLRMQDGCSG DLTLDENGWC RPKDNKTSDG YNDELEGILK
1160 1170 1180 1190 1200
KGFEDVTAKG SKRGRTMAFI SAVWCEMLRA YTVRSWEPFY KVFNRNMWMH
1210 1220 1230 1240 1250
LACSISATLT FLSTCIPGIT SILNTTCLLW WQYLLAIFWA LLNLFLDEIV
1260
PKVIYRRKYM TIKN
Length:1,264
Mass (Da):140,262
Last modified:June 8, 2016 - v1
Checksum:i638142BB1B433640
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN999947 Genomic DNA Translation: CZT99281.1

Genome annotation databases

EnsemblProtistsiCZT99281; CZT99281; PF3D7_1211900

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN999947 Genomic DNA Translation: CZT99281.1

3D structure databases

ProteinModelPortaliA0A143ZZK9
ModBaseiSearch...
MobiDBiSearch...

Chemistry databases

DrugBankiDB11638 Artenimol

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCZT99281; CZT99281; PF3D7_1211900

Family and domain databases

InterProiView protein in InterPro
IPR006068 ATPase_P-typ_cation-transptr_C
IPR004014 ATPase_P-typ_cation-transptr_N
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00689 Cation_ATPase_C, 1 hit
PF00690 Cation_ATPase_N, 1 hit
PRINTSiPR00120 HATPASE
SMARTiView protein in SMART
SM00831 Cation_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 2 hits
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 4 hits
TIGRFAMsiTIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A143ZZK9_PLAF7
AccessioniPrimary (citable) accession number: A0A143ZZK9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 8, 2016
Last sequence update: June 8, 2016
Last modified: May 23, 2018
This is version 15 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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