UniProtKB - A0A142CHG1 (A0A142CHG1_HUMAN)
Protein
Submitted name:
G-protein coupled receptor 139
Gene
GPR139
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- identical protein binding Source: Ensembl
- neuropeptide receptor activity Source: Ensembl
GO - Biological processi
Keywordsi
Molecular function | ReceptorImported, TransducerARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: G-protein coupled receptor 139Imported |
Gene namesi | Name:GPR139Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 30 – 51 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 63 – 87 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 107 – 128 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 148 – 166 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 182 – 208 | HelicalSequence analysisAdd BLAST | 27 | |
Transmembranei | 228 – 249 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 269 – 288 | HelicalSequence analysisAdd BLAST | 20 |
Keywords - Cellular componenti
MembraneInteractioni
GO - Molecular functioni
- identical protein binding Source: Ensembl
Chemistry databases
BindingDBi | A0A142CHG1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 43 – 285 | G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST | 243 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
OMAi | MQMPPVP |
OrthoDBi | 790152at2759 |
PhylomeDBi | A0A142CHG1 |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN |
PROSITEi | View protein in PROSITE PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A142CHG1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEHTHAHLAA NSSLSWWSPG SACGLGFVPV VYYSLLLCLG LPANILTVII
60 70 80 90 100
LSQLVARRQK SSYNYLLALA AADILVLFFI VFVDFLLEDF ILNMQMPQVP
110 120 130 140 150
DKIIEVLEFS SIHTSIWITV PLTIDRYIAV CHPLKYHTVS YPARTRKVIV
160 170 180 190 200
SVYITCFLTS IPYYWWPNIW TEDYISTSVH HVLIWIHCFT VYLVPCSIFF
210 220 230 240 250
ILNSIIVYKL RRKSNFRLRG YSTGKTTAIL FTITSIFATL WAPRIIMILY
260 270 280 290 300
HLYGAPIQNR WLVHIMSDIA NMLALLNTAI NFFLYCFISK RFRTMAAATL
310 320 330 340 350
KAFFKCQKQP VQFYTNHNFS ITSSPWISPA NSHCIKMLVY QYDKNGKPIK
VSP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | KR081941 mRNA Translation: AMQ09597.1 |
RefSeqi | NP_001002911.1, NM_001002911.3 |
Genome annotation databases
GeneIDi | 124274 |
KEGGi | hsa:124274 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | KR081941 mRNA Translation: AMQ09597.1 |
RefSeqi | NP_001002911.1, NM_001002911.3 |
3D structure databases
SMRi | A0A142CHG1 |
ModBasei | Search... |
Chemistry databases
BindingDBi | A0A142CHG1 |
Protocols and materials databases
Antibodypediai | 12144, 141 antibodies |
Genome annotation databases
GeneIDi | 124274 |
KEGGi | hsa:124274 |
Organism-specific databases
CTDi | 124274 |
Phylogenomic databases
OMAi | MQMPPVP |
OrthoDBi | 790152at2759 |
PhylomeDBi | A0A142CHG1 |
Miscellaneous databases
BioGRID-ORCSi | 124274, 3 hits in 836 CRISPR screens |
ChiTaRSi | GPR139, human |
GenomeRNAii | 124274 |
Gene expression databases
ExpressionAtlasi | A0A142CHG1, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN |
PROSITEi | View protein in PROSITE PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A142CHG1_HUMAN | |
Accessioni | A0A142CHG1Primary (citable) accession number: A0A142CHG1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 8, 2016 |
Last sequence update: | June 8, 2016 | |
Last modified: | December 2, 2020 | |
This is version 21 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |