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Protein
Submitted name:

MHC class I polypeptide-related sequence B

Gene

MICB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I polypeptide-related sequence BImported
Gene namesi
Name:MICBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:7091 MICB

Subcellular locationi

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500730555123 – 383Sequence analysisAdd BLAST361

Proteomic databases

EPDiA0A140T9M6
PeptideAtlasiA0A140T9M6

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini207 – 302Ig-likeInterPro annotationAdd BLAST96

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

PhylomeDBiA0A140T9M6

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.30.500.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.iShow all

A0A140T9M6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLGRVLLFL AVAFPFAPPA AAAEPHSLRY NLMVLSQDGS VQSGFLAEGH
60 70 80 90 100
LDGQPFLRYD RQKRRAKPQG QWAEDVLGAE TWDTETEDLT ENGQDLRRTL
110 120 130 140 150
THIKDQKGGL HSLQEIRVCE MHEDSSTRGS RHFYYNGELF LSQNLETQES
160 170 180 190 200
TVPQSSRAQT LAMNVTNFWK EDAMKTKTHY RAMQADCLQK LQRYLKSGVA
210 220 230 240 250
IRRTVPPMVN VTCSEVSEGN ITVTCRASSF YPRNITLTWR QDGVSLSHNT
260 270 280 290 300
QQWGDVLPDG NGTYQTWVAT RIRQGEEQRF TCYMEHSGNH GTHPVPSGKA
310 320 330 340 350
LVLQSQRTDF PYVSAAMPCF VIIIILCVPC CKKKTSAAEG PELVSLQVLD
360 370 380
QHPVGTGDHR DAAQLGFQPL MSATGSTGST EGA
Length:383
Mass (Da):42,564
Last modified:May 11, 2016 - v1
Checksum:i451F0584FD39572A
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q29980MICB_HUMAN
MHC class I polypeptide-related seq...
MICB PERB11.2
383Annotation score:
X6R344X6R344_HUMAN
MHC class I polypeptide-related seq...
MICB
383Annotation score:
A0A0G2JHB5A0A0G2JHB5_HUMAN
MHC class I polypeptide-related seq...
MICB
340Annotation score:
A0A0G2JH58A0A0G2JH58_HUMAN
MHC class I polypeptide-related seq...
MICB
383Annotation score:
A0A140T9D8A0A140T9D8_HUMAN
MHC class I polypeptide-related seq...
MICB
340Annotation score:
A0A0G2JH91A0A0G2JH91_HUMAN
MHC class I polypeptide-related seq...
MICB
340Annotation score:
F5H7Q8F5H7Q8_HUMAN
MHC class I polypeptide-related seq...
MICB
351Annotation score:
A0A140T979A0A140T979_HUMAN
MHC class I polypeptide-related seq...
MICB
360Annotation score:
A0A140T9H4A0A140T9H4_HUMAN
MHC class I polypeptide-related seq...
MICB
317Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662866 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000458032; ENSP00000407092; ENSG00000234218

Similar proteinsi

Entry informationi

Entry nameiA0A140T9M6_HUMAN
AccessioniPrimary (citable) accession number: A0A140T9M6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 11, 2016
Last sequence update: May 11, 2016
Last modified: May 23, 2018
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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