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Entry version 27 (02 Dec 2020)
Sequence version 1 (11 May 2016)
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Protein
Submitted name:

Glutamine-rich protein 2

Gene

Qrich2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Glutamine-rich protein 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Qrich2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2684912, Qrich2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A0A140LIY9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A140LIY9, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000091437

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
A0A140LIY9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A140LIY9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni60 – 89DisorderedSequence analysisAdd BLAST30
Regioni307 – 367DisorderedSequence analysisAdd BLAST61
Regioni482 – 507DisorderedSequence analysisAdd BLAST26
Regioni551 – 571DisorderedSequence analysisAdd BLAST21
Regioni592 – 611DisorderedSequence analysisAdd BLAST20
Regioni814 – 836DisorderedSequence analysisAdd BLAST23
Regioni1178 – 1218DisorderedSequence analysisAdd BLAST41
Regioni1297 – 1317DisorderedSequence analysisAdd BLAST21
Regioni1355 – 1417DisorderedSequence analysisAdd BLAST63
Regioni2233 – 2337DisorderedSequence analysisAdd BLAST105

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili204 – 231Sequence analysisAdd BLAST28
Coiled coili1623 – 1643Sequence analysisAdd BLAST21
Coiled coili1669 – 1693Sequence analysisAdd BLAST25
Coiled coili1718 – 1738Sequence analysisAdd BLAST21
Coiled coili1895 – 1915Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi307 – 327PolarSequence analysisAdd BLAST21
Compositional biasi2251 – 2269PolarSequence analysisAdd BLAST19
Compositional biasi2285 – 2313PolarSequence analysisAdd BLAST29

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R9P3, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161294

Identification of Orthologs from Complete Genome Data

More...
OMAi
MVQQGPV

Database of Orthologous Groups

More...
OrthoDBi
430976at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032013, DUF4795

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16043, DUF4795, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A140LIY9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPPSLVANRV SLRELADLAI GTPEVGAVNF TALHTLIVSI LKSLNLQEVL
60 70 80 90 100
IDFHYPSTET GRGTESLHGT HSAPHLPTSK EKHQSLPRLS QTPQELENQV
110 120 130 140 150
KDLGNQVLDL TKQFKTMDNK VQGMATQIDQ ISVPELQQEE EIALVTQQVS
160 170 180 190 200
LTKFSKIYES EEMMEKPEPT VKMPTEMVQL KPSRTPSLTK PTSVLQDLIE
210 220 230 240 250
DVKILKQASE LQELLQRFNE LEKLVKSREE YLDLLSRRLN LLAPGGEEIT
260 270 280 290 300
MVTWEELEQV IGDGWRASKG SSDSSTATVG KHKFTSSDLL PSGMFLRAAD
310 320 330 340 350
QALDSTGGIE RISSRDQSRS TTAFRDMARE PSQVISETDR QTYARRDEQL
360 370 380 390 400
PGQTQRGGIP RTEPFGMDQP RLIDAVMPTT TGQLGVKPPE MYGQELVPVD
410 420 430 440 450
KAQSGGLPPS GPDKELKKLS TIQLGTVPPS TYQQGMMLPG MDREGTEQAA
460 470 480 490 500
VRDSGQGPWP TAQQGLIAVG VDQHGLPIPG TGQQGLPPQH MDQRGLVTPG
510 520 530 540 550
TDQRAFSPSL SDERTLVSLG LMQVSTDQQG FRQSSLTSRF IQPGAEQLRV
560 570 580 590 600
EQRGVAQPGL DRRSSVPVGT ERRASLQALA EKRSSVPIEV EQQSLAQSRA
610 620 630 640 650
GQQGLGQPST VSGGLIQPGT DQHLVPPGVD QPSLIQPGAF PLSLAQLGAD
660 670 680 690 700
QQGLIQTDTG QPVWVQPSTD QSGGVQPGAY LPGWVQPSVD QRDLVQVGMD
710 720 730 740 750
QQELRQPGAV QPGLVQPGAY APGLMQVGAS QDGLLQPGMD QLGLVQPGTA
760 770 780 790 800
WSLVQPDVDQ LDMAQPHGIL PGLAQPRGVL PGMVQPGAVQ PGVLQPGAVQ
810 820 830 840 850
PGVLQPGAVQ PGVLQPGAAQ PGLVQPGAAQ PGLVQPGAAQ PGVLQAGAVQ
860 870 880 890 900
PGVLQAGAVQ PGMVQQGPVQ PGVLQAGAAQ PGMVHPGAAQ PGMVQPGSVQ
910 920 930 940 950
PGMVQLGAVQ PGVLQAGAVQ FGMVQPGAVE PGVLRAGAVQ LGMVQPGAVQ
960 970 980 990 1000
LGVFRAGAVQ PGVLQAGAVQ PGMVQQGPVQ PGVLQAGAVQ PGMVQQGPVQ
1010 1020 1030 1040 1050
PGVLQAGAVQ PGMVQQGPVQ PGVLQAGAVQ PGMVQQGPVQ PGVLQSGAVQ
1060 1070 1080 1090 1100
PGMVQPGILP SGWGQPVAYS LGLGQPGIGQ YGLVQPRVDR YGFVQPGVAR
1110 1120 1130 1140 1150
GLLQPSDSQR ALMQPGVGQV EWIQPGMSRR DLVQPGADES GLAQGGMAQQ
1160 1170 1180 1190 1200
GLVQSGMARQ GLAQPGMARQ GVAHPGMARQ GVAHPGKARQ GVAHPGKARQ
1210 1220 1230 1240 1250
GVAQPDLAQP GAPSEDKFGL AQPIVDQSAF MQPGMDQRGL VQPRMYQYGF
1260 1270 1280 1290 1300
VDPSDLQRNF LQPRGVLPRL VQPVVDQGGP LQAGLAQSRM VQPITDQRGP
1310 1320 1330 1340 1350
VQPETLQPRQ VQPSTSRRGL VQSLLTPYGL MQPGAAQLGL VQPGMEQLGE
1360 1370 1380 1390 1400
ERRGLLQPGM DQPGLLQPGT DQPGLLQPGA DQPGLLQPGA DQPGLLQPGA
1410 1420 1430 1440 1450
DQPGFLQPGA DQPGFLQPGA ARLDRIQPGM VEPGAGPQGL GQPDLAPPPF
1460 1470 1480 1490 1500
IHPGIFPRGI FQPATLPRGF RQPTPTQPDF VTPSIDLRFP TMEVEPQQPQ
1510 1520 1530 1540 1550
LPQLYQLPTA LQTRQGILPE GVHRISGQKA KTRTVEVQYD IEEAGLPEEV
1560 1570 1580 1590 1600
QRVEVDTQVS WELSHLDSAA PTAPEQVITD SRTQDSWNYL QQFSSVSETR
1610 1620 1630 1640 1650
REQQRQESLP PSFPMAVETL RLIGELISLY LELKEQLKDL DEELAGQTDF
1660 1670 1680 1690 1700
EKIQYLITMI VKKTIPQDLA EQLKSLKTLN KEVRQDKAKL EKIQKFVDSA
1710 1720 1730 1740 1750
ADTTGGKGVK PNHLSLQLGI LRVTVSDIEK ELNELRESQD RGKATMENSV
1760 1770 1780 1790 1800
SEASLYLQDQ LDKLRTIIES MLGSSSTLLS MSITPHKSTA CLVPGQIDPE
1810 1820 1830 1840 1850
ATCPACSLDV SHQVSLLVQR YEQLQDMVSG LAASRPSKKA KLQGQDEELL
1860 1870 1880 1890 1900
GHVQSAILQV QGDCEKLNIT TSNLIEDHRQ KQKDIEVLYQ GIERLDKEKA
1910 1920 1930 1940 1950
NREHLEMEID EKADKSALAS KVSRIQFDAT TEQLNHMMQE LVAKMSGQEQ
1960 1970 1980 1990 2000
DWQKLLDKLL AEMDSKLDRL ELDPLKQMLE DRWKSLRQQL KERPPLYQAD
2010 2020 2030 2040 2050
EAAAMRRQLL AHFHCLSCDR PLETTVTGQV ISVTPIISSM PGHRSVRPYT
2060 2070 2080 2090 2100
VFELEQIRQQ SRNLKLGSSF PRVDMSQMER SVGRLHSMHS RMLMDMEKVQ
2110 2120 2130 2140 2150
VHFGGSVKAS SQMIRELLHT QCLSHPCYKR GADTADYSYS TVSRRCGGSH
2160 2170 2180 2190 2200
TLTYPYRRNR PQHLSPLEEI QIAMKHDEVD ILGLDGHIYK GRMDTRLPGI
2210 2220 2230 2240 2250
LGKDAPGVTK HNKAKLQQLQ QLQQLQQLQQ LQQLQQAQHA RPHAHRQPSL
2260 2270 2280 2290 2300
GNMISPPSRP QSAQMIADSK AVPSGQKKDR PVSSEGRLLQ SNVSHSSIPT
2310 2320 2330
DIASLQGSQQ GLNMHIDVPP GEGLEEPTRG PRSTAAH
Length:2,337
Mass (Da):252,135
Last modified:May 11, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAAD623495AF42FF7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q3V2A7QRIC2_MOUSE
Glutamine-rich protein 2
Qrich2 Gm66
592Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL645851 Genomic DNA No translation available.
AL645861 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_011247256.1, XM_011248954.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000208602; ENSMUSP00000147009; ENSMUSG00000070331

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
217341

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645851 Genomic DNA No translation available.
AL645861 Genomic DNA No translation available.
RefSeqiXP_011247256.1, XM_011248954.2

3D structure databases

SMRiA0A140LIY9
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000091437

Proteomic databases

PaxDbiA0A140LIY9

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
19682, 17 antibodies

Genome annotation databases

EnsembliENSMUST00000208602; ENSMUSP00000147009; ENSMUSG00000070331
GeneIDi217341

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84074
MGIiMGI:2684912, Qrich2

Phylogenomic databases

eggNOGiENOG502R9P3, Eukaryota
GeneTreeiENSGT00940000161294
OMAiMVQQGPV
OrthoDBi430976at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
217341, 2 hits in 17 CRISPR screens
RNActiA0A140LIY9, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

ExpressionAtlasiA0A140LIY9, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR032013, DUF4795
PfamiView protein in Pfam
PF16043, DUF4795, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A140LIY9_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A140LIY9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 11, 2016
Last sequence update: May 11, 2016
Last modified: December 2, 2020
This is version 27 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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