Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 12 (11 Dec 2019)
Sequence version 1 (11 May 2016)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Reverse transcriptase domain-containing protein

Gene

TcasGA2_TC031763

Organism
Tribolium castaneum (Red flour beetle)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Reverse transcriptase domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:TcasGA2_TC031763Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTribolium castaneum (Red flour beetle)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7070 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaColeopteraPolyphagaCucujiformiaTenebrionidaeTenebrionidae incertae sedisTribolium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007266 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini783 – 1054Reverse transcriptaseInterPro annotationAdd BLAST272

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 46DisorderedSequence analysisAdd BLAST46

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili122 – 145Sequence analysisAdd BLAST24
Coiled coili637 – 657Sequence analysisAdd BLAST21
Coiled coili1296 – 1316Sequence analysisAdd BLAST21
Coiled coili1513 – 1540Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi29 – 46PolarSequence analysisAdd BLAST18

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.60.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036691 Endo/exonu/phosph_ase_sf
IPR005135 Endo/exonuclease/phosphatase
IPR000477 RT_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14529 Exo_endo_phos_2, 1 hit
PF00078 RVT_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56219 SSF56219, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50878 RT_POL, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A139W9J0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGKEHRKVV TDQGVGSPDP AGVELLARGS PRSSSSDRDA VRLGNQGTLQ
60 70 80 90 100
EIATGTVKKR GKDEGKPTGT TLVHSRLNFM VGNIQRSNSL SHAEKKRKYM
110 120 130 140 150
DTSAENLNPE DGVYIKKECP EVFVLKEELN QIVRLVKELE KKTGEMYNPK
160 170 180 190 200
KELVNLVSKL SRSVQVLNRT SILTWLENHR YEPVEKMTID ADVQTDAESS
210 220 230 240 250
GDEVQTKTPK ATMVDCATQI ENWSQRRPEL TTWTQVTNFK EFQEISKKEW
260 270 280 290 300
PSNIYSSTEI KIGNPLATKD SVVKVVFVEP EDTQMTRSIQ SLYKDRYPEL
310 320 330 340 350
LEIEEDYGTL EQVTKIGNME SRRKVIKILA TNPEDLWEKL NRLKENTDNG
360 370 380 390 400
EWIVMHHLTW MDNKQLQKVV EAVFHETETK VVVQSGGWYC DLRIDAAVKV
410 420 430 440 450
LSRAVSVIDC RSGNGFVWIE TDKYKIYSCY ISPNCAYEEY HETLERLRDH
460 470 480 490 500
LVVNRNRSLV TGDFNAKSYL WGNVSEDKRG KELADLIGEL EMWVLNQGNQ
510 520 530 540 550
PTFVRGQSSS IIDITFASPK VAQCVKGWHV HEDAPLGDHL PIVFALQPQR
560 570 580 590 600
NRANEGEPPS RWRWSETCRE RLFASLRNKL KSHMAISPEK LTSLVIEACK
610 620 630 640 650
ENLTRYESGG GSRRKVYWWN DQIRSSRTKC VKARRTLMRA NRRKRKEAIE
660 670 680 690 700
LMTLEADYAI AKKELRKQIK IAKDNAWKKL IDELEEDPWG KTYQVVMKKL
710 720 730 740 750
KRETPPTLNE KLRNVKALFP QKIPILWEPP MVQTWDPFTR EELATAAAKI
760 770 780 790 800
RVKKASGPDG IPPEVVRLAC EAVPEVVLGT MNRIMKSGVF PPNWKTARLV
810 820 830 840 850
LIPKKGMDEE GNRKMRPICL LDVFGKLLEH LIRARLNEDI DDNGGLSDQQ
860 870 880 890 900
FGFREGRCTL DAVTEVMKLA KFANNGTWGR KDYCALVTLD IENAFNSASW
910 920 930 940 950
LHIIEQLRRR GIKKELLRLI MSYLEGRRIE VTPNHIVDIT CGVPQGSVLG
960 970 980 990 1000
PSLWNILYDG VLKQDMPLGV KLVAFADDLA VAAIGRNEED LMRNTNQALA
1010 1020 1030 1040 1050
RVASWLEENE LKLAAEKTEA VLLVGRRRPR AVQFQIMGAK IEPKKVIKYL
1060 1070 1080 1090 1100
GIYIDQACTF SDHLAKTAAK AEGTISALSR IMPNIGGPGS NRRKLLAGVA
1110 1120 1130 1140 1150
TSMLLYGCEV WHTALATKKN VVVLESTHRR ILARVACAYR TVSTEAAQVI
1160 1170 1180 1190 1200
TGVPPARLLV EERVKQRCTG MSKSMARSHT LNLWQENWQQ TTKARWTRRL
1210 1220 1230 1240 1250
IPDIEKWVKR KHGEIDYHLT QALTGHGCFG TYLCRIGKIL NASCWYCGEE
1260 1270 1280 1290 1300
DTPSHTLFSC SYFDPLRMDV MKKILVWPEE TEKENLGPVI PVQCYRRRAA
1310 1320 1330 1340 1350
EALKIAENTI KNVIKENLGE KEAPQNTRPK KKKKTEDVCN SVKMDVRQTI
1360 1370 1380 1390 1400
YQMIKENTYV TIKGLKQVLE DKRIYQGSWS SLRRLLLSIG FHYKRDCNRR
1410 1420 1430 1440 1450
ALCEKPQIVS KRLNFLRKYK EYKAMNLYDF VFLDETWIFA KGGNRHSWQD
1460 1470 1480 1490 1500
DSIKSCRSAN VGSVVKGHKT SAEAEVPART TSRVGNDRGQ LDAILTTAVL
1510 1520 1530 1540 1550
AMTVSDREKM SVEEQQRQTI ANLEQQLAEA RAAQAALQSD RTGTRDIDAN
1560 1570 1580 1590 1600
IEEIKNTNLK LPSFWQRDPA LWFAQVEAQF HAYRIKADQS RYYTVVAALD
1610 1620 1630 1640 1650
CSVLQAVSDI LTNPPETNKY ETIKTKLISA YSDSQEKQLR RLLNELELGD
1660 1670 1680 1690 1700
RKPSQLLREM RTLAGVQVNE EVLRTLWLQR LPAQIHLWLS ASESTGIAVS
1710
NSRPSEMMAP D
Length:1,711
Mass (Da):195,011
Last modified:May 11, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i827D41DD7DF73653
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KQ972226 Genomic DNA Translation: KYB24577.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
TC031763_001; TC031763_001; TC031763

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KQ972226 Genomic DNA Translation: KYB24577.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblMetazoaiTC031763_001; TC031763_001; TC031763

Family and domain databases

Gene3Di3.60.10.10, 1 hit
InterProiView protein in InterPro
IPR036691 Endo/exonu/phosph_ase_sf
IPR005135 Endo/exonuclease/phosphatase
IPR000477 RT_dom
PfamiView protein in Pfam
PF14529 Exo_endo_phos_2, 1 hit
PF00078 RVT_1, 1 hit
SUPFAMiSSF56219 SSF56219, 1 hit
PROSITEiView protein in PROSITE
PS50878 RT_POL, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A139W9J0_TRICA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A139W9J0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 11, 2016
Last sequence update: May 11, 2016
Last modified: December 11, 2019
This is version 12 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again