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Protein
Submitted name:

OR2A7

Gene

OR2A7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer
Biological processOlfactionSAAS annotation, Sensory transduction

Names & Taxonomyi

Protein namesi
Submitted name:
OR2A7Imported
Gene namesi
Name:OR2A7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 50HelicalSequence analysisAdd BLAST26
Transmembranei56 – 77HelicalSequence analysisAdd BLAST22
Transmembranei98 – 119HelicalSequence analysisAdd BLAST22
Transmembranei131 – 161HelicalSequence analysisAdd BLAST31
Transmembranei199 – 224HelicalSequence analysisAdd BLAST26
Transmembranei236 – 260HelicalSequence analysisAdd BLAST25
Transmembranei272 – 291HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

ExpressionAtlasiA0A126GWD8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A126GWD8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 289G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST250

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

KOiK04257
OMAiIVISYMC
PhylomeDBiA0A126GWD8

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A126GWD8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDNITSITE FLLLGFPVGP RIQMLLFGLF SLFYVFTLLG NGTILGLISL
60 70 80 90 100
DSRLHAPMYF FLSHLAVVDI AYACNTVPRM LVNLLHPAKP ISFAGRMMQT
110 120 130 140 150
FLFSTFAVTE CLLLVVMSYD LYVAICHPLR YLAIMTWRVC ITLAVTSWTT
160 170 180 190 200
GVLLSLIHLV LLLPLPFCRP QKIYHFFCEI LAVLKLACAD THINENMVLA
210 220 230 240 250
GAISGLVGPL STIVVSYMCI LCAILQIQSR EVQRKAFCTC FSHLCVIGLF
260 270 280 290 300
YGTAIIMYVG PRYGNPKEQK KYLLLFHSLF NPMLNPLICS LRNSEVKNTL
310
KRVLGVERAL
Length:310
Mass (Da):34,742
Last modified:May 11, 2016 - v1
Checksum:iCEC80375FA7E6CF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KP290567 Genomic DNA Translation: ALI87725.1
RefSeqiNP_001005328.1, NM_001005328.1
XP_016885947.1, XM_017030458.1
UniGeneiHs.658609
Hs.745042

Genome annotation databases

GeneIDi401427
KEGGihsa:401427

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KP290567 Genomic DNA Translation: ALI87725.1
RefSeqiNP_001005328.1, NM_001005328.1
XP_016885947.1, XM_017030458.1
UniGeneiHs.658609
Hs.745042

3D structure databases

ProteinModelPortaliA0A126GWD8
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi401427
KEGGihsa:401427

Organism-specific databases

CTDi401427

Phylogenomic databases

KOiK04257
OMAiIVISYMC
PhylomeDBiA0A126GWD8

Gene expression databases

ExpressionAtlasiA0A126GWD8 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A126GWD8_HUMAN
AccessioniPrimary (citable) accession number: A0A126GWD8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 11, 2016
Last sequence update: May 11, 2016
Last modified: November 7, 2018
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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