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Protein

Olfactory receptor

Gene

OR4S2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processOlfactionUniRule annotationSAAS annotation, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:OR4S2Imported
ORF Names:hCG_2044351Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 45HelicalUniRule annotationAdd BLAST20
Transmembranei57 – 76HelicalUniRule annotationAdd BLAST20
Transmembranei96 – 121HelicalUniRule annotationAdd BLAST26
Transmembranei142 – 166HelicalUniRule annotationAdd BLAST25
Transmembranei204 – 223HelicalUniRule annotationAdd BLAST20
Transmembranei235 – 256HelicalUniRule annotationAdd BLAST22
Transmembranei268 – 287HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

PTM / Processingi

Proteomic databases

PRIDEiA0A126GVG1

Expressioni

Gene expression databases

ExpressionAtlasiA0A126GVG1 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 285G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST247

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

KOiK04257
OMAiWGLSQNL

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A126GVG1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKINNVTEF IFWGLSQSPE IEKVCFVVFS FFYIIILLGN LLIMLTVCLS
60 70 80 90 100
NLFKSPMYFF LSFLSFVDIC YSSVTAPKMI VDLLAKDKTI SYVGCMLQLF
110 120 130 140 150
GVHFFGCTEI FILTVMAYDR YVAICKPLHY MTIMNRETCN KMLLGTWVGG
160 170 180 190 200
FLHSIIQVAL VVQLPFCGPN EIDHYFCDVH PVLKLACTET YIVGVVVTAN
210 220 230 240 250
SGTIALGSFV ILLISYSIIL VSLRKQSAEG RRKALSTCGS HIAMVVIFFG
260 270 280 290 300
PCTFMYMRPD TTFSEDKMVA VFYTIITPML NPLIYTLRNA EVKNAMKKLW
310
GRNVFLEAKG K
Length:311
Mass (Da):35,172
Last modified:May 11, 2016 - v1
Checksum:iDAA0084EA91026D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KP290251 Genomic DNA Translation: ALI87431.1
CH471076 Genomic DNA Translation: EAW73678.1
RefSeqiNP_001004059.2, NM_001004059.2
UniGeneiHs.553621

Genome annotation databases

GeneIDi219431
KEGGihsa:219431

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KP290251 Genomic DNA Translation: ALI87431.1
CH471076 Genomic DNA Translation: EAW73678.1
RefSeqiNP_001004059.2, NM_001004059.2
UniGeneiHs.553621

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PRIDEiA0A126GVG1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi219431
KEGGihsa:219431

Organism-specific databases

CTDi219431

Phylogenomic databases

KOiK04257
OMAiWGLSQNL

Gene expression databases

ExpressionAtlasiA0A126GVG1 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A126GVG1_HUMAN
AccessioniPrimary (citable) accession number: A0A126GVG1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 11, 2016
Last sequence update: May 11, 2016
Last modified: November 7, 2018
This is version 24 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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