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Entry version 18 (22 Apr 2020)
Sequence version 1 (10 May 2017)
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Protein

Cytoplasmic envelopment protein 1

Gene

UL7

Organism
Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a critical role in cytoplasmic virus egress. Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm.UniRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cytoplasmic envelopment protein 1UniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:UL7Imported
ORF Names:HHV1gp012Imported, hmpv205_0007Imported, hmpv206_0007Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHuman herpesvirus 1 (HHV-1) (Human herpes simplex virus 1)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10298 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesHerpesviralesHerpesviridaeAlphaherpesvirinaeSimplexvirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiHomo sapiens (Human) [TaxID: 9606]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000126435 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome
  • UP000269540 Componenti: Genome
  • UP000180950 Componenti: Genome
  • UP000282049 Componenti: Genome
  • UP000180972 Componenti: Genome
  • UP000121444 Componenti: Genome
  • UP000107500 Componenti: Genome
  • UP000271107 Componenti: Genome
  • UP000180758 Componenti: Genome
  • UP000110586 Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Host cytoplasmUniRule annotation, Host Golgi apparatusUniRule annotation, Virion, Virion tegumentUniRule annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the herpesviridae cytoplasmic envelopment protein 1 family.UniRule annotation

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_04038 HSV_CEP1, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002600 Herpes_UL7

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01677 Herpes_UL7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A110B4Q7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAATADDEG SAATILKQAI AGDRSLVEAA EAISQQTLLR LACEVRQVGD
60 70 80 90 100
RQPRFTATSI ARVDVAPGCR LRFVLDGSPE DAYVTSEDYF KRCCGQSSYR
110 120 130 140 150
GFAVAVLTAN EDHVHSLAVP PLVLLHRFSL FNPRDLLDFE LACLLMYLEN
160 170 180 190 200
CPRSHATPST FAKVLAWLGV AGRRTSPFER VRCLFLRSCH WVLNTLMFMV
210 220 230 240 250
HVKPFDDEFV LPHWYMARYL LANNPPPVLS ALFCATPTSS SFRLPGPPPR
260 270 280 290
SDCVAYNPAG IMGSCWASEE VRAPLVYWWL SETPKRQTSS LFYQFC
Length:296
Mass (Da):33,033
Last modified:May 10, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3B99FAE81CDB8E82
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GU734771 Genomic DNA Translation: ADD60025.1
GU734772 Genomic DNA Translation: ADD60102.1
HM585498 Genomic DNA Translation: ADM22482.1
HM585502 Genomic DNA Translation: ADM22789.1
HM585510 Genomic DNA Translation: ADM23397.1
HM585511 Genomic DNA Translation: ADM23471.1
JN555585 Genomic DNA Translation: AEQ77037.1
JN400093 Genomic DNA Translation: AER37591.1
JQ673480 Genomic DNA Translation: AFE62834.1
JQ780693 Genomic DNA Translation: AFI23597.1
KM222721 Genomic DNA Translation: AJE59951.1
KM222723 Genomic DNA Translation: AJE60093.1
KM222724 Genomic DNA Translation: AJE60164.1
KM222725 Genomic DNA Translation: AJE60237.1
KT425108 Genomic DNA Translation: ALM22649.1
KT425110 Genomic DNA Translation: ALM22797.1
KT899744 Genomic DNA Translation: ALO18603.1
KT887224 Genomic DNA Translation: ALO18679.1
KU310660 Genomic DNA Translation: AMB65824.1
KX791795 Genomic DNA Translation: AOY34071.1
KX791823 Genomic DNA Translation: AOY34118.1
KX424525 Genomic DNA Translation: ARB08897.1
MF156584 Genomic DNA Translation: ASM47835.1
KY922718 Genomic DNA Translation: ATD84692.1
KY922719 Genomic DNA Translation: ATD84769.1
MH160360 Genomic DNA Translation: AWO69211.1
MH160363 Genomic DNA Translation: AWO69508.1
MH160368 Genomic DNA Translation: AWO69987.1
MH160371 Genomic DNA Translation: AWO70262.1
MH160374 Genomic DNA Translation: AWO70541.1
MH160376 Genomic DNA Translation: AWO70729.1
MH160378 Genomic DNA Translation: AWO70910.1
MH160381 Genomic DNA Translation: AWO71187.1
MH160384 Genomic DNA Translation: AWO71467.1
MH160389 Genomic DNA Translation: AWO71923.1
MH160390 Genomic DNA Translation: AWO72019.1
MG999838 Genomic DNA Translation: AWW07773.1
MG999846 Genomic DNA Translation: AWW08569.1
MG999848 Genomic DNA Translation: AWW08756.1
MG999858 Genomic DNA Translation: AWW09651.1
MG999863 Genomic DNA Translation: AWW10101.1
MG999864 Genomic DNA Translation: AWW10198.1
MG999865 Genomic DNA Translation: AWW10280.1
MG999866 Genomic DNA Translation: AWW10370.1
MG999870 Genomic DNA Translation: AWW10723.1
MG999871 Genomic DNA Translation: AWW10803.1
MG999873 Genomic DNA Translation: AWW11027.1
MG999877 Genomic DNA Translation: AWW11392.1
MG999883 Genomic DNA Translation: AWW11944.1
MG999886 Genomic DNA Translation: AWW12201.1
MG999889 Genomic DNA Translation: AWW12453.1
MG999897 Genomic DNA Translation: AWW13191.1
MG999898 Genomic DNA Translation: AWW13273.1
MH999842 Genomic DNA Translation: QAU09577.1
MH999843 Genomic DNA Translation: QAU09654.1
MH999846 Genomic DNA Translation: QAU09885.1
MH999847 Genomic DNA Translation: QAU09962.1
MH999851 Genomic DNA Translation: QAU10265.1
MN159376 Genomic DNA Translation: QEU44911.1
MN159377 Genomic DNA Translation: QEU44986.1
MN159378 Genomic DNA Translation: QEU45062.1
MN159379 Genomic DNA Translation: QEU45138.1
MN159380 Genomic DNA Translation: QEU45215.1
MN159381 Genomic DNA Translation: QEU45290.1
MN159382 Genomic DNA Translation: QEU45366.1
LT594106 Genomic DNA Translation: SBS69151.1
LT594107 Genomic DNA Translation: SBS69180.1
LT594109 Genomic DNA Translation: SBS69253.1

NCBI Reference Sequences

More...
RefSeqi
YP_009137081.1, NC_001806.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2703431

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vg:2703431

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU734771 Genomic DNA Translation: ADD60025.1
GU734772 Genomic DNA Translation: ADD60102.1
HM585498 Genomic DNA Translation: ADM22482.1
HM585502 Genomic DNA Translation: ADM22789.1
HM585510 Genomic DNA Translation: ADM23397.1
HM585511 Genomic DNA Translation: ADM23471.1
JN555585 Genomic DNA Translation: AEQ77037.1
JN400093 Genomic DNA Translation: AER37591.1
JQ673480 Genomic DNA Translation: AFE62834.1
JQ780693 Genomic DNA Translation: AFI23597.1
KM222721 Genomic DNA Translation: AJE59951.1
KM222723 Genomic DNA Translation: AJE60093.1
KM222724 Genomic DNA Translation: AJE60164.1
KM222725 Genomic DNA Translation: AJE60237.1
KT425108 Genomic DNA Translation: ALM22649.1
KT425110 Genomic DNA Translation: ALM22797.1
KT899744 Genomic DNA Translation: ALO18603.1
KT887224 Genomic DNA Translation: ALO18679.1
KU310660 Genomic DNA Translation: AMB65824.1
KX791795 Genomic DNA Translation: AOY34071.1
KX791823 Genomic DNA Translation: AOY34118.1
KX424525 Genomic DNA Translation: ARB08897.1
MF156584 Genomic DNA Translation: ASM47835.1
KY922718 Genomic DNA Translation: ATD84692.1
KY922719 Genomic DNA Translation: ATD84769.1
MH160360 Genomic DNA Translation: AWO69211.1
MH160363 Genomic DNA Translation: AWO69508.1
MH160368 Genomic DNA Translation: AWO69987.1
MH160371 Genomic DNA Translation: AWO70262.1
MH160374 Genomic DNA Translation: AWO70541.1
MH160376 Genomic DNA Translation: AWO70729.1
MH160378 Genomic DNA Translation: AWO70910.1
MH160381 Genomic DNA Translation: AWO71187.1
MH160384 Genomic DNA Translation: AWO71467.1
MH160389 Genomic DNA Translation: AWO71923.1
MH160390 Genomic DNA Translation: AWO72019.1
MG999838 Genomic DNA Translation: AWW07773.1
MG999846 Genomic DNA Translation: AWW08569.1
MG999848 Genomic DNA Translation: AWW08756.1
MG999858 Genomic DNA Translation: AWW09651.1
MG999863 Genomic DNA Translation: AWW10101.1
MG999864 Genomic DNA Translation: AWW10198.1
MG999865 Genomic DNA Translation: AWW10280.1
MG999866 Genomic DNA Translation: AWW10370.1
MG999870 Genomic DNA Translation: AWW10723.1
MG999871 Genomic DNA Translation: AWW10803.1
MG999873 Genomic DNA Translation: AWW11027.1
MG999877 Genomic DNA Translation: AWW11392.1
MG999883 Genomic DNA Translation: AWW11944.1
MG999886 Genomic DNA Translation: AWW12201.1
MG999889 Genomic DNA Translation: AWW12453.1
MG999897 Genomic DNA Translation: AWW13191.1
MG999898 Genomic DNA Translation: AWW13273.1
MH999842 Genomic DNA Translation: QAU09577.1
MH999843 Genomic DNA Translation: QAU09654.1
MH999846 Genomic DNA Translation: QAU09885.1
MH999847 Genomic DNA Translation: QAU09962.1
MH999851 Genomic DNA Translation: QAU10265.1
MN159376 Genomic DNA Translation: QEU44911.1
MN159377 Genomic DNA Translation: QEU44986.1
MN159378 Genomic DNA Translation: QEU45062.1
MN159379 Genomic DNA Translation: QEU45138.1
MN159380 Genomic DNA Translation: QEU45215.1
MN159381 Genomic DNA Translation: QEU45290.1
MN159382 Genomic DNA Translation: QEU45366.1
LT594106 Genomic DNA Translation: SBS69151.1
LT594107 Genomic DNA Translation: SBS69180.1
LT594109 Genomic DNA Translation: SBS69253.1
RefSeqiYP_009137081.1, NC_001806.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

GeneIDi2703431
KEGGivg:2703431

Family and domain databases

HAMAPiMF_04038 HSV_CEP1, 1 hit
InterProiView protein in InterPro
IPR002600 Herpes_UL7
PfamiView protein in Pfam
PF01677 Herpes_UL7, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A110B4Q7_HHV1
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A110B4Q7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: April 22, 2020
This is version 18 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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