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Protein

DNA ligase

Gene

PBK173_000429900

Organism
Plasmodium berghei
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:PBK173_000429900Imported, PBNK65E_000419300Imported, PBNK65NY_000418600Imported, PBSP11A_000419000Imported, PBSP11RLL_000418600Imported
OrganismiPlasmodium bergheiImported
Taxonomic identifieri5821 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Vinckeia)
Proteomesi
  • UP000069549 Componenti: Chromosome 14
  • UP000219860 Componenti: Chromosome 14
  • UP000219974 Componenti: Chromosome 14
  • UP000220214 Componenti: Chromosome 14

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_501424303218 – 898DNA ligaseSequence analysisAdd BLAST881

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini628 – 764DNA_LIGASE_A3InterPro annotationAdd BLAST137

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili874 – 894Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Family and domain databases

Gene3Di1.10.3260.10, 2 hits
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0Z0AAY9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLLLLILLT KMFFCKIKRY MRTEYNYVTP FMKSKLFHNY KNKFNVIILK
60 70 80 90 100
NIRNNVPNRN DKYLKCLSFP KKLDGGEQCD TKIEETHVKN EEKEASKRKN
110 120 130 140 150
TNDDSAKTKK SKVKNENEIK KGSLFNCKVY EDEKISDLTS PKFNPANFDI
160 170 180 190 200
SNLCLSEKDK IKHKFKDSLL FTFLTNTFNQ IEELKGSGAG SKKNVAIILS
210 220 230 240 250
NVFRVLIYYS PNDLIPAVYI TLNKVAPDYQ NVEAGVGEAL ILKTMSEAYS
260 270 280 290 300
RTETSIKKDL QQIEDLGIIA ESCSCKMRTI FPLPRLTIQS VFNELKSIPN
310 320 330 340 350
ISGSNSQQKK REVIKKLLVS AKTSEAKYIV RFLQQRLRIG VNSATVLQAL
360 370 380 390 400
AYAFVLTRPE IPENIIKDGK MMNEKLLNEQ TMVKGDKDNC NDGTTEVKNE
410 420 430 440 450
NDIKLEKQND TDNKTNMLDI DQFNNLVKSI KIRNERMSKP NLFFNIGKEG
460 470 480 490 500
DTRLLPIFKE LKNAYCDINN DSDIFECMEK SVKSALCELP NIEMIIQNLL
510 520 530 540 550
SGDDMNVLMK KCTVKTGVPV QPMLAKPTKG IQEVLDRFNN VTFTCEYKYD
560 570 580 590 600
GERAQIHYID KDNIKIFSRN LETMTEKYPD VIQIVKDQIM PGVTESIIDS
610 620 630 640 650
EVVAYDIENK KILPFQILTT RKRKDVDIEN IKVKICLFPF DLICCNGIPV
660 670 680 690 700
IKEPLEIRRK LLYSLLKCKE GVLEYATHSE MNNIDDIDIF LQDAIENNCE
710 720 730 740 750
GLMVKTLLDN ASYEPSRRSL NWLKVKKDYI EGLSDSVDLV PIAGYYGKGK
760 770 780 790 800
RSGVYGAFVL AAYNSETENF QTVCKAGTGF SDEILNALHE SLSDKIIPNK
810 820 830 840 850
KSYYEVSDKL NPDVWFDAHY VWEIKAADLS LSPVHTAAIG VYSDDKGIGL
860 870 880 890
RFPRFLRLRD DKNPEQATTA QQIVEFYEAQ FASKKNKNNN YNDESGSE
Length:898
Mass (Da):102,703
Last modified:April 13, 2016 - v1
Checksum:i5B58CBA8A84118B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LT160034 Genomic DNA Translation: CXJ10194.1
LT608150 Genomic DNA Translation: SCM25939.1
LT614640 Genomic DNA Translation: SCN28192.1
LT608278 Genomic DNA Translation: SCO62394.1
LT608262 Genomic DNA Translation: SCO63952.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LT160034 Genomic DNA Translation: CXJ10194.1
LT608150 Genomic DNA Translation: SCM25939.1
LT614640 Genomic DNA Translation: SCN28192.1
LT608278 Genomic DNA Translation: SCO62394.1
LT608262 Genomic DNA Translation: SCO63952.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.3260.10, 2 hits
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0Z0AAY9_PLABE
AccessioniPrimary (citable) accession number: A0A0Z0AAY9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 13, 2016
Last sequence update: April 13, 2016
Last modified: November 7, 2018
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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