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Protein

tRNA-dihydrouridine synthase

Gene

dus_3

Organism
Streptococcus pneumoniae
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.UniRule annotation

Cofactori

FMNUniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei102Proton donorUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
Biological processtRNA processingUniRule annotation
LigandFlavoprotein, FMNUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA-dihydrouridine synthaseUniRule annotation (EC:1.3.1.-UniRule annotation)
Gene namesi
Name:dus_3Imported
ORF Names:ERS409593_05580Imported
OrganismiStreptococcus pneumoniaeImported
Taxonomic identifieri1313 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000249256 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the dus family.UniRule annotation

Family and domain databases

CDDicd02801 DUS_like_FMN, 1 hit
Gene3Di1.10.1200.80, 1 hit
3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR035587 DUS-like_FMN-bd
IPR024036 tRNA-dHydroUridine_Synthase_C
IPR004652 tRNA_dU_NifR3
IPR001269 tRNA_hU_synthase
IPR018517 tRNA_hU_synthase_CS
PANTHERiPTHR11082 PTHR11082, 1 hit
PTHR11082:SF25 PTHR11082:SF25, 1 hit
PfamiView protein in Pfam
PF01207 Dus, 1 hit
PIRSFiPIRSF006621 Dus, 1 hit
TIGRFAMsiTIGR00737 nifR3_yhdG, 1 hit
PROSITEiView protein in PROSITE
PS01136 UPF0034, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0X9VK35-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFKIGDIEIK NKVVLAPMAG VCNSAFRLTV KEFGAGLVCA EMVSDKAILI
60 70 80 90 100
NNARTMGMLY IDEREKPLSL QIFGGEKDTL VEAAKFVDQN TTADIIDINM
110 120 130 140 150
GCPVPKITKC DAGAKWLLDP NKIYEMVSAV VDAVDKPVTV KMRMGWDEDH
160 170 180 190 200
IFAIDNARAV ERAGGQAVAL HGRTRVQMYE GTANWDIIKE VKQSVSIPVI
210 220 230 240 250
GNGDVKTPQD AKRMLDETGA DAVMIGRAAL GNPWMIYRTV HYLETGELKE
260 270 280 290 300
EPNVREKMSV CKLHLDRLID LKGEHVAVRE MRKHAAWYLK GVRGNADVRN
310 320 330
QINQSETRAE LVKVLDDFTI EAEAKELQRI KVG
Length:333
Mass (Da):37,037
Last modified:April 13, 2016 - v1
Checksum:i33F6EC9B579F4808
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FCSL01000021 Genomic DNA Translation: CVO55860.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FCSL01000021 Genomic DNA Translation: CVO55860.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd02801 DUS_like_FMN, 1 hit
Gene3Di1.10.1200.80, 1 hit
3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR035587 DUS-like_FMN-bd
IPR024036 tRNA-dHydroUridine_Synthase_C
IPR004652 tRNA_dU_NifR3
IPR001269 tRNA_hU_synthase
IPR018517 tRNA_hU_synthase_CS
PANTHERiPTHR11082 PTHR11082, 1 hit
PTHR11082:SF25 PTHR11082:SF25, 1 hit
PfamiView protein in Pfam
PF01207 Dus, 1 hit
PIRSFiPIRSF006621 Dus, 1 hit
TIGRFAMsiTIGR00737 nifR3_yhdG, 1 hit
PROSITEiView protein in PROSITE
PS01136 UPF0034, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0X9VK35_STREE
AccessioniPrimary (citable) accession number: A0A0X9VK35
Entry historyiIntegrated into UniProtKB/TrEMBL: April 13, 2016
Last sequence update: April 13, 2016
Last modified: October 10, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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